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Journal Abstract Search


238 related items for PubMed ID: 12065407

  • 1. INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence.
    Brookes S, Rowe J, Ruas M, Llanos S, Clark PA, Lomax M, James MC, Vatcheva R, Bates S, Vousden KH, Parry D, Gruis N, Smit N, Bergman W, Peters G.
    EMBO J; 2002 Jun 17; 21(12):2936-45. PubMed ID: 12065407
    [Abstract] [Full Text] [Related]

  • 2. Modulation of the expression of p16INK4a and p14ARF by hnRNP A1 and A2 RNA binding proteins: implications for cellular senescence.
    Zhu D, Xu G, Ghandhi S, Hubbard K.
    J Cell Physiol; 2002 Oct 17; 193(1):19-25. PubMed ID: 12209876
    [Abstract] [Full Text] [Related]

  • 3. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
    Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H.
    Genes Dev; 2002 Nov 15; 16(22):2923-34. PubMed ID: 12435633
    [Abstract] [Full Text] [Related]

  • 4. Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts.
    Huot TJ, Rowe J, Harland M, Drayton S, Brookes S, Gooptu C, Purkis P, Fried M, Bataille V, Hara E, Newton-Bishop J, Peters G.
    Mol Cell Biol; 2002 Dec 15; 22(23):8135-43. PubMed ID: 12417717
    [Abstract] [Full Text] [Related]

  • 5. The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
    Sharpless NE, Ramsey MR, Balasubramanian P, Castrillon DH, DePinho RA.
    Oncogene; 2004 Jan 15; 23(2):379-85. PubMed ID: 14724566
    [Abstract] [Full Text] [Related]

  • 6. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.
    Peeper DS, Shvarts A, Brummelkamp T, Douma S, Koh EY, Daley GQ, Bernards R.
    Nat Cell Biol; 2002 Feb 15; 4(2):148-53. PubMed ID: 11812999
    [Abstract] [Full Text] [Related]

  • 7. Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.
    Milyavsky M, Shats I, Erez N, Tang X, Senderovich S, Meerson A, Tabach Y, Goldfinger N, Ginsberg D, Harris CC, Rotter V.
    Cancer Res; 2003 Nov 01; 63(21):7147-57. PubMed ID: 14612508
    [Abstract] [Full Text] [Related]

  • 8. Contribution of p16(INK4a) to replicative senescence of human fibroblasts.
    Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J, Peters G.
    Exp Cell Res; 2004 Aug 15; 298(2):549-59. PubMed ID: 15265701
    [Abstract] [Full Text] [Related]

  • 9. Upregulation of chicken p15INK4b at senescence and in the developing brain.
    Kim SH, Rowe J, Fujii H, Jones R, Schmierer B, Kong BW, Kuchler K, Foster D, Ish-Horowicz D, Peters G.
    J Cell Sci; 2006 Jun 15; 119(Pt 12):2435-43. PubMed ID: 16720639
    [Abstract] [Full Text] [Related]

  • 10. The INK4a/ARF locus and melanoma.
    Sharpless E, Chin L.
    Oncogene; 2003 May 19; 22(20):3092-8. PubMed ID: 12789286
    [Abstract] [Full Text] [Related]

  • 11. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.
    D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG.
    Cancer Res; 2004 Jun 15; 64(12):4122-30. PubMed ID: 15205322
    [Abstract] [Full Text] [Related]

  • 12. Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock.
    Munro J, Barr NI, Ireland H, Morrison V, Parkinson EK.
    Exp Cell Res; 2004 May 01; 295(2):525-38. PubMed ID: 15093749
    [Abstract] [Full Text] [Related]

  • 13. Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis.
    Kanellou P, Zaravinos A, Zioga M, Stratigos A, Baritaki S, Soufla G, Zoras O, Spandidos DA.
    Cancer Lett; 2008 Jun 08; 264(1):145-61. PubMed ID: 18331779
    [Abstract] [Full Text] [Related]

  • 14. Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.
    Palmero I, Murga M, Zubiaga A, Serrano M.
    Oncogene; 2002 May 02; 21(19):2939-47. PubMed ID: 12082524
    [Abstract] [Full Text] [Related]

  • 15. Prognostic significance of p14ARF, p15INK4b, and p16INK4a inactivation in malignant peripheral nerve sheath tumors.
    Endo M, Kobayashi C, Setsu N, Takahashi Y, Kohashi K, Yamamoto H, Tamiya S, Matsuda S, Iwamoto Y, Tsuneyoshi M, Oda Y.
    Clin Cancer Res; 2011 Jun 01; 17(11):3771-82. PubMed ID: 21262917
    [Abstract] [Full Text] [Related]

  • 16. Telomerase activity is sufficient to bypass replicative senescence in human limbal and conjunctival but not corneal keratinocytes.
    Pellegrini G, Dellambra E, Paterna P, Golisano O, Traverso CE, Rama P, Lacal P, De Luca M.
    Eur J Cell Biol; 2004 Dec 01; 83(11-12):691-700. PubMed ID: 15679113
    [Abstract] [Full Text] [Related]

  • 17. Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
    Krimpenfort P, Quon KC, Mooi WJ, Loonstra A, Berns A.
    Nature; 2001 Sep 06; 413(6851):83-6. PubMed ID: 11544530
    [Abstract] [Full Text] [Related]

  • 18. A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.
    Shvarts A, Brummelkamp TR, Scheeren F, Koh E, Daley GQ, Spits H, Bernards R.
    Genes Dev; 2002 Mar 15; 16(6):681-6. PubMed ID: 11914273
    [Abstract] [Full Text] [Related]

  • 19. Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes.
    Drayton S, Rowe J, Jones R, Vatcheva R, Cuthbert-Heavens D, Marshall J, Fried M, Peters G.
    Cancer Cell; 2003 Oct 15; 4(4):301-10. PubMed ID: 14585357
    [Abstract] [Full Text] [Related]

  • 20. Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.
    Takaoka M, Harada H, Deramaudt TB, Oyama K, Andl CD, Johnstone CN, Rhoades B, Enders GH, Opitz OG, Nakagawa H.
    Oncogene; 2004 Sep 02; 23(40):6760-8. PubMed ID: 15273725
    [Abstract] [Full Text] [Related]


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