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279 related items for PubMed ID: 12070027

  • 1. Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.
    Derenne S, Monia B, Dean NM, Taylor JK, Rapp MJ, Harousseau JL, Bataille R, Amiot M.
    Blood; 2002 Jul 01; 100(1):194-9. PubMed ID: 12070027
    [Abstract] [Full Text] [Related]

  • 2. Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.
    Song L, Coppola D, Livingston S, Cress D, Haura EB.
    Cancer Biol Ther; 2005 Mar 01; 4(3):267-76. PubMed ID: 15753661
    [Abstract] [Full Text] [Related]

  • 3. Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.
    Puthier D, Derenne S, Barillé S, Moreau P, Harousseau JL, Bataille R, Amiot M.
    Br J Haematol; 1999 Nov 01; 107(2):392-5. PubMed ID: 10583232
    [Abstract] [Full Text] [Related]

  • 4. Myeloid cell factor-1 is a critical survival factor for multiple myeloma.
    Zhang B, Gojo I, Fenton RG.
    Blood; 2002 Mar 15; 99(6):1885-93. PubMed ID: 11877256
    [Abstract] [Full Text] [Related]

  • 5. The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical-dependent and Jun NH2-terminal kinase-dependent mechanism.
    Pei XY, Dai Y, Grant S.
    Mol Cancer Ther; 2004 Dec 15; 3(12):1513-24. PubMed ID: 15634644
    [Abstract] [Full Text] [Related]

  • 6. Potentiation of dexamethasone-, paclitaxel-, and Ad-p53-induced apoptosis by Bcl-2 antisense oligodeoxynucleotides in drug-resistant multiple myeloma cells.
    Liu Q, Gazitt Y.
    Blood; 2003 May 15; 101(10):4105-14. PubMed ID: 12521996
    [Abstract] [Full Text] [Related]

  • 7. The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells.
    Gomez-Bougie P, Bataille R, Amiot M.
    Eur J Immunol; 2004 Nov 15; 34(11):3156-64. PubMed ID: 15459900
    [Abstract] [Full Text] [Related]

  • 8. VEGF induces Mcl-1 up-regulation and protects multiple myeloma cells against apoptosis.
    Le Gouill S, Podar K, Amiot M, Hideshima T, Chauhan D, Ishitsuka K, Kumar S, Raje N, Richardson PG, Harousseau JL, Anderson KC.
    Blood; 2004 Nov 01; 104(9):2886-92. PubMed ID: 15217829
    [Abstract] [Full Text] [Related]

  • 9. Bone marrow microenvironment-derived signals induce Mcl-1 dependence in multiple myeloma.
    Gupta VA, Matulis SM, Conage-Pough JE, Nooka AK, Kaufman JL, Lonial S, Boise LH.
    Blood; 2017 Apr 06; 129(14):1969-1979. PubMed ID: 28151428
    [Abstract] [Full Text] [Related]

  • 10. Chemosensitization of myeloma plasma cells by an antisense-mediated downregulation of Bcl-2 protein.
    van de Donk NW, Kamphuis MM, van Dijk M, Borst HP, Bloem AC, Lokhorst HM.
    Leukemia; 2003 Jan 06; 17(1):211-9. PubMed ID: 12529680
    [Abstract] [Full Text] [Related]

  • 11. A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells.
    Yamanaka K, Rocchi P, Miyake H, Fazli L, Vessella B, Zangemeister-Wittke U, Gleave ME.
    Mol Cancer Ther; 2005 Nov 06; 4(11):1689-98. PubMed ID: 16275990
    [Abstract] [Full Text] [Related]

  • 12. Mcl-1 blocks radiation-induced apoptosis and inhibits clonogenic cell death.
    Skvara H, Thallinger C, Wacheck V, Monia BP, Pehamberger H, Jansen B, Selzer E.
    Anticancer Res; 2005 Nov 06; 25(4):2697-703. PubMed ID: 16080514
    [Abstract] [Full Text] [Related]

  • 13. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P, Wuillème-Toumi S, Ménoret E, Trichet V, Robillard N, Philippe M, Bataille R, Amiot M.
    Cancer Res; 2007 Jun 01; 67(11):5418-24. PubMed ID: 17545623
    [Abstract] [Full Text] [Related]

  • 14. Role of bcl-X(L) in the control of apoptosis in murine myeloma cells.
    Gauthier ER, Piché L, Lemieux G, Lemieux R.
    Cancer Res; 1996 Mar 15; 56(6):1451-6. PubMed ID: 8640839
    [Abstract] [Full Text] [Related]

  • 15. Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model.
    Thallinger C, Wolschek MF, Wacheck V, Maierhofer H, Günsberg P, Polterauer P, Pehamberger H, Monia BP, Selzer E, Wolff K, Jansen B.
    J Invest Dermatol; 2003 Jun 15; 120(6):1081-6. PubMed ID: 12787138
    [Abstract] [Full Text] [Related]

  • 16. Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor.
    Muto A, Hori M, Sasaki Y, Saitoh A, Yasuda I, Maekawa T, Uchida T, Asakura K, Nakazato T, Kaneda T, Kizaki M, Ikeda Y, Yoshida T.
    Mol Cancer Ther; 2007 Mar 15; 6(3):987-94. PubMed ID: 17363492
    [Abstract] [Full Text] [Related]

  • 17. Antisense-mediated downregulation of anti-apoptotic proteins induces apoptosis and sensitizes head and neck squamous cell carcinoma cells to chemotherapy.
    Sharma H, Sen S, Lo Muzio L, Mariggiò A, Singh N.
    Cancer Biol Ther; 2005 Jul 15; 4(7):720-7. PubMed ID: 15917659
    [Abstract] [Full Text] [Related]

  • 18. Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.
    Aichberger KJ, Mayerhofer M, Krauth MT, Skvara H, Florian S, Sonneck K, Akgul C, Derdak S, Pickl WF, Wacheck V, Selzer E, Monia BP, Moriggl R, Valent P, Sillaber C.
    Blood; 2005 Apr 15; 105(8):3303-11. PubMed ID: 15626746
    [Abstract] [Full Text] [Related]

  • 19. Mcl-1 mediates cytokine deprivation induced apoptosis of human myeloma cell line XG-7.
    Song L, Li Y, Sun Y, Shen B.
    Chin Med J (Engl); 2002 Aug 15; 115(8):1241-3. PubMed ID: 12215301
    [Abstract] [Full Text] [Related]

  • 20. Survival of Mycobacterium tuberculosis in host macrophages involves resistance to apoptosis dependent upon induction of antiapoptotic Bcl-2 family member Mcl-1.
    Sly LM, Hingley-Wilson SM, Reiner NE, McMaster WR.
    J Immunol; 2003 Jan 01; 170(1):430-7. PubMed ID: 12496428
    [Abstract] [Full Text] [Related]

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