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245 related items for PubMed ID: 12079364

  • 1. Mutations that reduce aggregation of the Alzheimer's Abeta42 peptide: an unbiased search for the sequence determinants of Abeta amyloidogenesis.
    Wurth C, Guimard NK, Hecht MH.
    J Mol Biol; 2002 Jun 21; 319(5):1279-90. PubMed ID: 12079364
    [Abstract] [Full Text] [Related]

  • 2. Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities.
    de Groot NS, Aviles FX, Vendrell J, Ventura S.
    FEBS J; 2006 Feb 21; 273(3):658-68. PubMed ID: 16420488
    [Abstract] [Full Text] [Related]

  • 3. Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide.
    Kim W, Hecht MH.
    Proc Natl Acad Sci U S A; 2006 Oct 24; 103(43):15824-9. PubMed ID: 17038501
    [Abstract] [Full Text] [Related]

  • 4. A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide.
    Kim W, Kim Y, Min J, Kim DJ, Chang YT, Hecht MH.
    ACS Chem Biol; 2006 Aug 22; 1(7):461-9. PubMed ID: 17168524
    [Abstract] [Full Text] [Related]

  • 5. Conversion of Abeta42 into a folded soluble native-like protein using a semi-random library of amphipathic helices.
    Arslan PE, Mulligan VK, Ho S, Chakrabartty A.
    J Mol Biol; 2010 Mar 12; 396(5):1284-94. PubMed ID: 20026077
    [Abstract] [Full Text] [Related]

  • 6. Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis.
    Kirkitadze MD, Condron MM, Teplow DB.
    J Mol Biol; 2001 Oct 05; 312(5):1103-19. PubMed ID: 11580253
    [Abstract] [Full Text] [Related]

  • 7. Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding.
    Bateman DA, McLaurin J, Chakrabartty A.
    BMC Neurosci; 2007 May 02; 8():29. PubMed ID: 17475015
    [Abstract] [Full Text] [Related]

  • 8. Probing Alzheimer amyloid peptide aggregation using a cell-free fluorescent protein refolding method.
    Arslan PE, Chakrabartty A.
    Biochem Cell Biol; 2009 Aug 02; 87(4):631-9. PubMed ID: 19767826
    [Abstract] [Full Text] [Related]

  • 9. Identification of physiological and toxic conformations in Abeta42 aggregates.
    Masuda Y, Uemura S, Ohashi R, Nakanishi A, Takegoshi K, Shimizu T, Shirasawa T, Irie K.
    Chembiochem; 2009 Jan 26; 10(2):287-95. PubMed ID: 19115328
    [Abstract] [Full Text] [Related]

  • 10. Conformational dynamics of amyloid beta-protein assembly probed using intrinsic fluorescence.
    Maji SK, Amsden JJ, Rothschild KJ, Condron MM, Teplow DB.
    Biochemistry; 2005 Oct 11; 44(40):13365-76. PubMed ID: 16201761
    [Abstract] [Full Text] [Related]

  • 11. Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity.
    Wilhelmus MM, Boelens WC, Otte-Höller I, Kamps B, de Waal RM, Verbeek MM.
    Brain Res; 2006 May 17; 1089(1):67-78. PubMed ID: 16635482
    [Abstract] [Full Text] [Related]

  • 12. Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity.
    Feng Y, Yang SG, Du XT, Zhang X, Sun XX, Zhao M, Sun GY, Liu RT.
    Biochem Biophys Res Commun; 2009 Dec 25; 390(4):1250-4. PubMed ID: 19878655
    [Abstract] [Full Text] [Related]

  • 13. In vitro and in vivo staining characteristics of small, fluorescent, Abeta42-binding D-enantiomeric peptides in transgenic AD mouse models.
    van Groen T, Kadish I, Wiesehan K, Funke SA, Willbold D.
    ChemMedChem; 2009 Feb 25; 4(2):276-82. PubMed ID: 19072935
    [Abstract] [Full Text] [Related]

  • 14. Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display.
    Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D.
    Chembiochem; 2003 Aug 04; 4(8):748-53. PubMed ID: 12898626
    [Abstract] [Full Text] [Related]

  • 15. Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.
    Takahashi T, Mihara H.
    Acc Chem Res; 2008 Oct 04; 41(10):1309-18. PubMed ID: 18937396
    [Abstract] [Full Text] [Related]

  • 16. Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.
    Kim W, Hecht MH.
    J Biol Chem; 2005 Oct 14; 280(41):35069-76. PubMed ID: 16079141
    [Abstract] [Full Text] [Related]

  • 17. Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation.
    Bieschke J, Zhang Q, Powers ET, Lerner RA, Kelly JW.
    Biochemistry; 2005 Apr 05; 44(13):4977-83. PubMed ID: 15794636
    [Abstract] [Full Text] [Related]

  • 18. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest.
    McLaurin J, Franklin T, Chakrabartty A, Fraser PE.
    J Mol Biol; 1998 Apr 24; 278(1):183-94. PubMed ID: 9571042
    [Abstract] [Full Text] [Related]

  • 19. Key residues for the oligomerization of Aβ42 protein in Alzheimer's disease.
    Ngo S, Guo Z.
    Biochem Biophys Res Commun; 2011 Oct 28; 414(3):512-6. PubMed ID: 21986527
    [Abstract] [Full Text] [Related]

  • 20. Rational design of amyloid beta peptide-binding proteins: pseudo-Abeta beta-sheet surface presented in green fluorescent protein binds tightly and preferentially to structured Abeta.
    Takahashi T, Ohta K, Mihara H.
    Proteins; 2010 Feb 01; 78(2):336-47. PubMed ID: 19731370
    [Abstract] [Full Text] [Related]

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