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Journal Abstract Search


414 related items for PubMed ID: 12095614

  • 1. Direct addition of BimL to mitochondria does not lead to cytochrome c release.
    Terradillos O, Montessuit S, Huang DC, Martinou JC.
    FEBS Lett; 2002 Jul 03; 522(1-3):29-34. PubMed ID: 12095614
    [Abstract] [Full Text] [Related]

  • 2. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
    Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ.
    Cancer Cell; 2002 Sep 03; 2(3):183-92. PubMed ID: 12242151
    [Abstract] [Full Text] [Related]

  • 3. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.
    Mol Cell; 2001 Sep 03; 8(3):705-11. PubMed ID: 11583631
    [Abstract] [Full Text] [Related]

  • 4. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 5. Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity.
    Shimizu S, Tsujimoto Y.
    Proc Natl Acad Sci U S A; 2000 Jan 18; 97(2):577-82. PubMed ID: 10639121
    [Abstract] [Full Text] [Related]

  • 6. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD.
    Mol Cell; 2005 Feb 18; 17(4):525-35. PubMed ID: 15721256
    [Abstract] [Full Text] [Related]

  • 7. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 8. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.
    Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.
    J Biol Chem; 2002 Jun 21; 277(25):22781-8. PubMed ID: 11929871
    [Abstract] [Full Text] [Related]

  • 9. Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.
    Yamaguchi H, Wang HG.
    J Biol Chem; 2002 Nov 01; 277(44):41604-12. PubMed ID: 12198137
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of Bax-induced cytochrome c release from neural cell and brain mitochondria by dibucaine and propranolol.
    Polster BM, Basañez G, Young M, Suzuki M, Fiskum G.
    J Neurosci; 2003 Apr 01; 23(7):2735-43. PubMed ID: 12684459
    [Abstract] [Full Text] [Related]

  • 11. Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.
    Kim TH, Zhao Y, Barber MJ, Kuharsky DK, Yin XM.
    J Biol Chem; 2000 Dec 15; 275(50):39474-81. PubMed ID: 10982793
    [Abstract] [Full Text] [Related]

  • 12. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 13. Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells.
    Shimizu S, Matsuoka Y, Shinohara Y, Yoneda Y, Tsujimoto Y.
    J Cell Biol; 2001 Jan 22; 152(2):237-50. PubMed ID: 11266442
    [Abstract] [Full Text] [Related]

  • 14. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis.
    Desagher S, Osen-Sand A, Nichols A, Eskes R, Montessuit S, Lauper S, Maundrell K, Antonsson B, Martinou JC.
    J Cell Biol; 1999 Mar 08; 144(5):891-901. PubMed ID: 10085289
    [Abstract] [Full Text] [Related]

  • 15. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
    [Abstract] [Full Text] [Related]

  • 16. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 23; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 17. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 18. Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death.
    Shangary S, Johnson DE.
    Biochemistry; 2002 Jul 30; 41(30):9485-95. PubMed ID: 12135371
    [Abstract] [Full Text] [Related]

  • 19. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 30; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

  • 20. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
    Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH.
    Cell Death Differ; 2000 Dec 30; 7(12):1166-73. PubMed ID: 11175253
    [Abstract] [Full Text] [Related]


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