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Journal Abstract Search

1153 related items for PubMed ID: 12097282

  • 1. Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.
    Lokker NA, Sullivan CM, Hollenbach SJ, Israel MA, Giese NA.
    Cancer Res; 2002 Jul 01; 62(13):3729-35. PubMed ID: 12097282
    [Abstract] [Full Text] [Related]

  • 2. Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation.
    Servidei T, Riccardi A, Sanguinetti M, Dominici C, Riccardi R.
    J Cell Physiol; 2006 Jul 01; 208(1):220-8. PubMed ID: 16575905
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
    Shawver LK, Schwartz DP, Mann E, Chen H, Tsai J, Chu L, Taylorson L, Longhi M, Meredith S, Germain L, Jacobs JS, Tang C, Ullrich A, Berens ME, Hersh E, McMahon G, Hirth KP, Powell TJ.
    Clin Cancer Res; 1997 Jul 01; 3(7):1167-77. PubMed ID: 9815796
    [Abstract] [Full Text] [Related]

  • 4. Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family.
    Brave SR, Ratcliffe K, Wilson Z, James NH, Ashton S, Wainwright A, Kendrew J, Dudley P, Broadbent N, Sproat G, Taylor S, Barnes C, Silva JC, Farnsworth CL, Hennequin L, Ogilvie DJ, Jürgensmeier JM, Shibuya M, Wedge SR, Barry ST.
    Mol Cancer Ther; 2011 May 01; 10(5):861-73. PubMed ID: 21441409
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571.
    McGary EC, Weber K, Mills L, Doucet M, Lewis V, Lev DC, Fidler IJ, Bar-Eli M.
    Clin Cancer Res; 2002 Nov 01; 8(11):3584-91. PubMed ID: 12429650
    [Abstract] [Full Text] [Related]

  • 6. Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury.
    Yu JC, Lokker NA, Hollenbach S, Apatira M, Li J, Betz A, Sedlock D, Oda S, Nomoto Y, Matsuno K, Ide S, Tsukuda E, Giese NA.
    J Pharmacol Exp Ther; 2001 Sep 01; 298(3):1172-8. PubMed ID: 11504817
    [Abstract] [Full Text] [Related]

  • 7. Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells.
    Dong Y, Jia L, Wang X, Tan X, Xu J, Deng Z, Jiang T, Rainov NG, Li B, Ren H.
    Int J Oncol; 2011 Feb 01; 38(2):555-69. PubMed ID: 21152856
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.
    Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ.
    Clin Cancer Res; 2003 Dec 15; 9(17):6534-44. PubMed ID: 14695158
    [Abstract] [Full Text] [Related]

  • 9. Transforming growth factor beta as a potential tumor progression factor among hyperdiploid glioblastoma cultures: evidence for the role of platelet-derived growth factor.
    Jennings MT, Hart CE, Commers PA, Whitlock JA, Martincic D, Maciunas RJ, Moots PL, Shehab TM.
    J Neurooncol; 1997 Feb 15; 31(3):233-54. PubMed ID: 9049853
    [Abstract] [Full Text] [Related]

  • 10. Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.
    Yu JC, Gutkind JS, Mahadevan D, Li W, Meyers KA, Pierce JH, Heidaran MA.
    J Cell Biol; 1994 Oct 15; 127(2):479-87. PubMed ID: 7929590
    [Abstract] [Full Text] [Related]

  • 11. Platelet-derived growth factor activates porcine thecal cell phosphatidylinositol-3-kinase-Akt/PKB and ras-extracellular signal-regulated kinase-1/2 kinase signaling pathways via the platelet-derived growth factor-beta receptor.
    Taylor CC.
    Endocrinology; 2000 Apr 15; 141(4):1545-53. PubMed ID: 10746662
    [Abstract] [Full Text] [Related]

  • 12. Chemosensitization by STI571 targeting the platelet-derived growth factor/platelet-derived growth factor receptor-signaling pathway in the tumor progression and angiogenesis of gastric carcinoma.
    Kim R, Emi M, Arihiro K, Tanabe K, Uchida Y, Toge T.
    Cancer; 2005 May 01; 103(9):1800-9. PubMed ID: 15786421
    [Abstract] [Full Text] [Related]

  • 13. Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.
    Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA.
    Oncogene; 2003 Apr 17; 22(15):2334-42. PubMed ID: 12700668
    [Abstract] [Full Text] [Related]

  • 14. Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes.
    Artemenko Y, Gagnon A, Sorisky A.
    J Cell Physiol; 2009 Jan 17; 218(1):228-36. PubMed ID: 18814181
    [Abstract] [Full Text] [Related]

  • 15. Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).
    Ahn HY, Hadizadeh KR, Seul C, Yun YP, Vetter H, Sachinidis A.
    Mol Biol Cell; 1999 Apr 17; 10(4):1093-104. PubMed ID: 10198059
    [Abstract] [Full Text] [Related]

  • 16. Compartmentalization of autocrine signal transduction pathways in Sis-transformed NIH 3T3 cells.
    Valgeirsdóttir S, Eriksson A, Nistér M, Heldin CH, Westermark B, Claesson-Welsh L.
    J Biol Chem; 1995 Apr 28; 270(17):10161-70. PubMed ID: 7730319
    [Abstract] [Full Text] [Related]

  • 17. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
    Chaudhary LR, Hruska KA.
    J Cell Biochem; 2001 Mar 26; 81(2):304-11. PubMed ID: 11241670
    [Abstract] [Full Text] [Related]

  • 18. Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.
    Kilic T, Alberta JA, Zdunek PR, Acar M, Iannarelli P, O'Reilly T, Buchdunger E, Black PM, Stiles CD.
    Cancer Res; 2000 Sep 15; 60(18):5143-50. PubMed ID: 11016641
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of platelet-derived growth factor receptor tyrosine kinase and downstream signaling pathways by Compound C.
    Kwon HJ, Kim GE, Lee YT, Jeong MS, Kang I, Yang D, Yeo EJ.
    Cell Signal; 2013 Apr 15; 25(4):883-97. PubMed ID: 23277201
    [Abstract] [Full Text] [Related]

  • 20. Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells.
    Chen YC, Chang CN, Hsu HC, Chiou SJ, Lee LT, Hseu TH.
    Life Sci; 2009 Jun 19; 84(25-26):915-22. PubMed ID: 19393247
    [Abstract] [Full Text] [Related]

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