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838 related items for PubMed ID: 12107550

  • 1. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
    Jacobson PA, Green K, Birnbaum A, Remmel RP.
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):461-7. PubMed ID: 12107550
    [Abstract] [Full Text] [Related]

  • 2. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J, Innocenti F, Schuetz EG, Flockhart DA, Relling MV, Santucci R, Ratain MJ.
    Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 4. Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.
    Rae JM, Soukhova NV, Flockhart DA, Desta Z.
    Drug Metab Dispos; 2002 May; 30(5):525-30. PubMed ID: 11950782
    [Abstract] [Full Text] [Related]

  • 5. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.
    Bae SH, Kwon MJ, Choi EJ, Zheng YF, Yoon KD, Liu KH, Bae SK.
    Chem Biol Interact; 2013 Sep 05; 205(1):11-9. PubMed ID: 23777987
    [Abstract] [Full Text] [Related]

  • 6. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep 05; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 7. Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.
    Granvil CP, Madan A, Sharkawi M, Parkinson A, Wainer IW.
    Drug Metab Dispos; 1999 Apr 05; 27(4):533-41. PubMed ID: 10101149
    [Abstract] [Full Text] [Related]

  • 8. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
    Kiang TK, Ho PC, Anari MR, Tong V, Abbott FS, Chang TK.
    Toxicol Sci; 2006 Dec 05; 94(2):261-71. PubMed ID: 16945988
    [Abstract] [Full Text] [Related]

  • 9. Investigation of the major human hepatic cytochrome P450 involved in 4-hydroxylation and N-dechloroethylation of trofosfamide.
    May-Manke A, Kroemer H, Hempel G, Bohnenstengel F, Hohenlöchter B, Blaschke G, Boos J.
    Cancer Chemother Pharmacol; 1999 Dec 05; 44(4):327-34. PubMed ID: 10447581
    [Abstract] [Full Text] [Related]

  • 10. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A, Satoh H, Thomas PE, Bush E, Moore D.
    Drug Metab Dispos; 1996 Sep 05; 24(9):940-7. PubMed ID: 8886602
    [Abstract] [Full Text] [Related]

  • 11. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK, Moon JK, Chang CH, Choi H, Park HW, Park BS, Lee HS, Hwang EC, Lee YD, Liu KH, Kim JH.
    Drug Metab Dispos; 2006 Jul 05; 34(7):1090-5. PubMed ID: 16581944
    [Abstract] [Full Text] [Related]

  • 12. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
    Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.
    Drug Metab Dispos; 2010 Jan 05; 38(1):92-9. PubMed ID: 19812348
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct 05; 34(10):1779-85. PubMed ID: 16855053
    [Abstract] [Full Text] [Related]

  • 14. Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.
    Sahi J, Black CB, Hamilton GA, Zheng X, Jolley S, Rose KA, Gilbert D, LeCluyse EL, Sinz MW.
    Drug Metab Dispos; 2003 Apr 05; 31(4):439-46. PubMed ID: 12642470
    [Abstract] [Full Text] [Related]

  • 15. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer.
    Roy P, Tretyakov O, Wright J, Waxman DJ.
    Drug Metab Dispos; 1999 Nov 05; 27(11):1309-18. PubMed ID: 10534317
    [Abstract] [Full Text] [Related]

  • 16. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D.
    Drug Metab Dispos; 1997 May 05; 25(5):623-30. PubMed ID: 9152603
    [Abstract] [Full Text] [Related]

  • 17. Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide.
    Huang Z, Roy P, Waxman DJ.
    Biochem Pharmacol; 2000 Apr 15; 59(8):961-72. PubMed ID: 10692561
    [Abstract] [Full Text] [Related]

  • 18. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.
    Gerber JG, Rhodes RJ, Gal J.
    Chirality; 2004 Jan 15; 16(1):36-44. PubMed ID: 14628297
    [Abstract] [Full Text] [Related]

  • 19. Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation.
    Chang Y, Fang WB, Lin SN, Moody DE.
    Basic Clin Pharmacol Toxicol; 2011 Jan 15; 108(1):55-62. PubMed ID: 20825389
    [Abstract] [Full Text] [Related]

  • 20. Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.
    Hijazi Y, Boulieu R.
    Drug Metab Dispos; 2002 Jul 15; 30(7):853-8. PubMed ID: 12065445
    [Abstract] [Full Text] [Related]

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