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367 related items for PubMed ID: 12110583

  • 1. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis.
    Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, Yang X.
    EMBO J; 2002 Jul 15; 21(14):3704-14. PubMed ID: 12110583
    [Abstract] [Full Text] [Related]

  • 2. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex.
    Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S.
    J Biol Chem; 2001 Jun 08; 276(23):20633-40. PubMed ID: 11279218
    [Abstract] [Full Text] [Related]

  • 3. Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines.
    Shain KH, Landowski TH, Dalton WS.
    J Immunol; 2002 Mar 01; 168(5):2544-53. PubMed ID: 11859150
    [Abstract] [Full Text] [Related]

  • 4. The role of c-FLIP in modulation of CD95-induced apoptosis.
    Scaffidi C, Schmitz I, Krammer PH, Peter ME.
    J Biol Chem; 1999 Jan 15; 274(3):1541-8. PubMed ID: 9880531
    [Abstract] [Full Text] [Related]

  • 5. Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short).
    Chatterjee D, Schmitz I, Krueger A, Yeung K, Kirchhoff S, Krammer PH, Peter ME, Wyche JH, Pantazis P.
    Cancer Res; 2001 Oct 01; 61(19):7148-54. PubMed ID: 11585748
    [Abstract] [Full Text] [Related]

  • 6. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
    Micheau O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, Briand C, Grütter MG.
    J Biol Chem; 2002 Nov 22; 277(47):45162-71. PubMed ID: 12215447
    [Abstract] [Full Text] [Related]

  • 7. TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity.
    Kirchhoff S, Müller WW, Krueger A, Schmitz I, Krammer PH.
    J Immunol; 2000 Dec 01; 165(11):6293-300. PubMed ID: 11086065
    [Abstract] [Full Text] [Related]

  • 8. Regulation of the Fas death pathway by FLICE-inhibitory protein in primary human B cells.
    Hennino A, Berard M, Casamayor-Pallejà M, Krammer PH, Defrance T.
    J Immunol; 2000 Sep 15; 165(6):3023-30. PubMed ID: 10975811
    [Abstract] [Full Text] [Related]

  • 9. Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
    Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H.
    J Biol Chem; 2001 Aug 31; 276(35):32585-90. PubMed ID: 11384965
    [Abstract] [Full Text] [Related]

  • 10. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.
    Fulda S, Meyer E, Debatin KM.
    Cancer Res; 2000 Jul 15; 60(14):3947-56. PubMed ID: 10919673
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.
    Gómez-Angelats M, Cidlowski JA.
    J Biol Chem; 2001 Nov 30; 276(48):44944-52. PubMed ID: 11581255
    [Abstract] [Full Text] [Related]

  • 12. c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
    Mathas S, Lietz A, Anagnostopoulos I, Hummel F, Wiesner B, Janz M, Jundt F, Hirsch B, Jöhrens-Leder K, Vornlocher HP, Bommert K, Stein H, Dörken B.
    J Exp Med; 2004 Apr 19; 199(8):1041-52. PubMed ID: 15078899
    [Abstract] [Full Text] [Related]

  • 13. Activation of caspases-8 and -10 by FLIP(L).
    Boatright KM, Deis C, Denault JB, Sutherlin DP, Salvesen GS.
    Biochem J; 2004 Sep 01; 382(Pt 2):651-7. PubMed ID: 15209560
    [Abstract] [Full Text] [Related]

  • 14. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.
    Scaffidi C, Schmitz I, Zha J, Korsmeyer SJ, Krammer PH, Peter ME.
    J Biol Chem; 1999 Aug 06; 274(32):22532-8. PubMed ID: 10428830
    [Abstract] [Full Text] [Related]

  • 15. Constitutive caspase activation and impaired death-inducing signaling complex formation in CD95-resistant, long-term activated, antigen-specific T cells.
    Strauss G, Knape I, Melzner I, Debatin KM.
    J Immunol; 2003 Aug 01; 171(3):1172-82. PubMed ID: 12874203
    [Abstract] [Full Text] [Related]

  • 16. Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression.
    Kinoshita H, Yoshikawa H, Shiiki K, Hamada Y, Nakajima Y, Tasaka K.
    Int J Cancer; 2000 Dec 15; 88(6):986-91. PubMed ID: 11093825
    [Abstract] [Full Text] [Related]

  • 17. Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.
    Sharp DA, Lawrence DA, Ashkenazi A.
    J Biol Chem; 2005 May 13; 280(19):19401-9. PubMed ID: 15760909
    [Abstract] [Full Text] [Related]

  • 18. N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway.
    Kataoka T, Tschopp J.
    Mol Cell Biol; 2004 Apr 13; 24(7):2627-36. PubMed ID: 15024054
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of death receptor signals by cellular FLIP.
    Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J.
    Nature; 1997 Jul 10; 388(6638):190-5. PubMed ID: 9217161
    [Abstract] [Full Text] [Related]

  • 20. FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis.
    Hennino A, Bérard M, Krammer PH, Defrance T.
    J Exp Med; 2001 Feb 19; 193(4):447-58. PubMed ID: 11181697
    [Abstract] [Full Text] [Related]

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