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176 related items for PubMed ID: 12115729

  • 1. Induction or suppression of expression of cytochrome C oxidase subunit II by heregulin beta 1 in human mammary epithelial cells is dependent on the levels of ErbB2 expression.
    Sun Y, Lin H, Zhu Y, Ma C, Ye J, Luo J.
    J Cell Physiol; 2002 Aug; 192(2):225-33. PubMed ID: 12115729
    [Abstract] [Full Text] [Related]

  • 2. Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells.
    Ram TG, Hosick HL, Ethier SP.
    J Cell Physiol; 2000 Jun; 183(3):301-13. PubMed ID: 10797304
    [Abstract] [Full Text] [Related]

  • 3. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase.
    Tan M, Grijalva R, Yu D.
    Cancer Res; 1999 Apr 01; 59(7):1620-5. PubMed ID: 10197638
    [Abstract] [Full Text] [Related]

  • 4. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.
    Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX.
    Cancer Res; 1996 Mar 15; 56(6):1457-65. PubMed ID: 8640840
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of ErbB2 enhances ethanol-stimulated intracellular signaling and invasion of human mammary epithelial and breast cancer cells in vitro.
    Ma C, Lin H, Leonard SS, Shi X, Ye J, Luo J.
    Oncogene; 2003 Aug 14; 22(34):5281-90. PubMed ID: 12917629
    [Abstract] [Full Text] [Related]

  • 6. A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4.
    Lee H, Akita RW, Sliwkowski MX, Maihle NJ.
    Cancer Res; 2001 Jun 01; 61(11):4467-73. PubMed ID: 11389077
    [Abstract] [Full Text] [Related]

  • 7. Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.
    Pan MH, Lin CC, Lin JK, Chen WJ.
    J Agric Food Chem; 2007 Jun 27; 55(13):5030-7. PubMed ID: 17539658
    [Abstract] [Full Text] [Related]

  • 8. The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
    Motoyama AB, Hynes NE, Lane HA.
    Cancer Res; 2002 Jun 01; 62(11):3151-8. PubMed ID: 12036928
    [Abstract] [Full Text] [Related]

  • 9. Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175.
    Schaefer G, Fitzpatrick VD, Sliwkowski MX.
    Oncogene; 1997 Sep 18; 15(12):1385-94. PubMed ID: 9333014
    [Abstract] [Full Text] [Related]

  • 10. Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer.
    Yonezawa M, Wada K, Tatsuguchi A, Akamatsu T, Gudis K, Seo T, Mitsui K, Nagata K, Tanaka S, Fujimori S, Sakamoto C.
    Digestion; 2009 Sep 18; 80(4):215-25. PubMed ID: 19797898
    [Abstract] [Full Text] [Related]

  • 11. Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification.
    Ram TG, Schelling ME, Hosick HL.
    Cell Growth Differ; 2000 Mar 18; 11(3):173-83. PubMed ID: 10768865
    [Abstract] [Full Text] [Related]

  • 12. Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells.
    Ram TG, Kokeny KE, Dilts CA, Ethier SP.
    J Cell Physiol; 1995 Jun 18; 163(3):589-96. PubMed ID: 7775601
    [Abstract] [Full Text] [Related]

  • 13. Transcriptional up-regulation of paxillin expression by heregulin in human breast cancer cells.
    Vadlamudi R, Adam L, Tseng B, Costa L, Kumar R.
    Cancer Res; 1999 Jun 15; 59(12):2843-6. PubMed ID: 10383144
    [Abstract] [Full Text] [Related]

  • 14. Interactions between progestins and heregulin (HRG) signaling pathways: HRG acts as mediator of progestins proliferative effects in mouse mammary adenocarcinomas.
    Balañá ME, Lupu R, Labriola L, Charreau EH, Elizalde PV.
    Oncogene; 1999 Nov 04; 18(46):6370-9. PubMed ID: 10597237
    [Abstract] [Full Text] [Related]

  • 15. Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity.
    Altiok N, Altiok S, Changeux JP.
    EMBO J; 1997 Feb 17; 16(4):717-25. PubMed ID: 9049301
    [Abstract] [Full Text] [Related]

  • 16. Heregulin regulation of autocrine motility factor expression in human tumor cells.
    Talukder AH, Adam L, Raz A, Kumar R.
    Cancer Res; 2000 Jan 15; 60(2):474-80. PubMed ID: 10667603
    [Abstract] [Full Text] [Related]

  • 17. Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016.
    Xia W, Liu LH, Ho P, Spector NL.
    Oncogene; 2004 Jan 22; 23(3):646-53. PubMed ID: 14737100
    [Abstract] [Full Text] [Related]

  • 18. Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): increased invasiveness may contribute to poor prognosis.
    Xu FJ, Stack S, Boyer C, O'Briant K, Whitaker R, Mills GB, Yu YH, Bast RC.
    Clin Cancer Res; 1997 Sep 22; 3(9):1629-34. PubMed ID: 9815853
    [Abstract] [Full Text] [Related]

  • 19. Expression of heregulin by mouse mammary tumor cells: role in activation of ErbB receptors.
    Schmitt M, Walker MP, Richards RG, Bocchinfuso WP, Fukuda T, Medina D, Kittrell FS, Korach KS, DiAugustine RP.
    Mol Carcinog; 2006 Jul 22; 45(7):490-505. PubMed ID: 16482517
    [Abstract] [Full Text] [Related]

  • 20. Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
    Belsches-Jablonski AP, Biscardi JS, Peavy DR, Tice DA, Romney DA, Parsons SJ.
    Oncogene; 2001 Mar 22; 20(12):1465-75. PubMed ID: 11313890
    [Abstract] [Full Text] [Related]


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