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Journal Abstract Search


302 related items for PubMed ID: 12117590

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  • 3. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison.
    Ballard TM, Woolley ML, Prinssen E, Huwyler J, Porter R, Spooren W.
    Psychopharmacology (Berl); 2005 Apr; 179(1):218-29. PubMed ID: 15739074
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  • 6. The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles.
    Varty GB, Grilli M, Forlani A, Fredduzzi S, Grzelak ME, Guthrie DH, Hodgson RA, Lu SX, Nicolussi E, Pond AJ, Parker EM, Hunter JC, Higgins GA, Reggiani A, Bertorelli R.
    Psychopharmacology (Berl); 2005 Apr; 179(1):207-17. PubMed ID: 15682298
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  • 9. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.
    Tatarczyńska E, Klodzińska A, Chojnacka-Wójcik E, Palucha A, Gasparini F, Kuhn R, Pilc A.
    Br J Pharmacol; 2001 Apr; 132(7):1423-30. PubMed ID: 11264235
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  • 10. The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety.
    Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, Bristow LJ, Varney MA, Cosford ND.
    Neuropsychopharmacology; 2004 Nov; 29(11):1971-9. PubMed ID: 15305166
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  • 11. Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic-pituitary-adrenal axis activity: interaction with serotonergic systems.
    Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Schaffhauser H, Rao SP, Varney MA, Anderson JJ.
    Neuropharmacology; 2003 Apr; 44(5):562-72. PubMed ID: 12668042
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  • 13. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide].
    Satow A, Maehara S, Ise S, Hikichi H, Fukushima M, Suzuki G, Kimura T, Tanak T, Ito S, Kawamoto H, Ohta H.
    J Pharmacol Exp Ther; 2008 Aug; 326(2):577-86. PubMed ID: 18487514
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  • 17. The modified Geller-Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation.
    Paterson NE, Hanania T.
    Behav Brain Res; 2010 Mar 17; 208(1):258-64. PubMed ID: 20006648
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  • 18. The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats.
    Rutten K, Van Der Kam EL, De Vry J, Bruckmann W, Tzschentke TM.
    Addict Biol; 2011 Jan 17; 16(1):108-15. PubMed ID: 20579001
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  • 19. The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats.
    Li X, Kaczanowska K, Finn MG, Markou A, Risbrough VB.
    Neuropharmacology; 2015 Oct 17; 97():357-64. PubMed ID: 26002628
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