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PUBMED FOR HANDHELDS

Journal Abstract Search


226 related items for PubMed ID: 12119004

  • 1. Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
    Yao J, Chang M, Li Y, Pisha E, Liu X, Yao D, Elguindi EC, Blond SY, Bolton JL.
    Chem Res Toxicol; 2002 Jul; 15(7):935-42. PubMed ID: 12119004
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  • 2. Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.
    Chang M, Shin YG, van Breemen RB, Blond SY, Bolton JL.
    Biochemistry; 2001 Apr 17; 40(15):4811-20. PubMed ID: 11294649
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  • 3. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
    Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL.
    Chem Res Toxicol; 1998 Jul 17; 11(7):758-65. PubMed ID: 9671538
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  • 5. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.
    Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL.
    Chem Res Toxicol; 2003 May 17; 16(5):668-75. PubMed ID: 12755597
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  • 10. Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin.
    Li Y, Yao J, Chang M, Cuendet M, Bolton JL.
    Toxicol Lett; 2004 Dec 30; 154(3):225-33. PubMed ID: 15501614
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  • 11. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus.
    Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, Bolton JL, Thatcher GR.
    J Biol Chem; 2009 Mar 27; 284(13):8633-42. PubMed ID: 19158089
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  • 12. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
    Liu X, Yao J, Pisha E, Yang Y, Hua Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 2002 Apr 27; 15(4):512-9. PubMed ID: 11952337
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  • 13. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
    Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 1999 Feb 27; 12(2):204-13. PubMed ID: 10027800
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  • 14. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.
    Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL.
    Chem Res Toxicol; 1998 Sep 27; 11(9):1105-11. PubMed ID: 9760286
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  • 16. Response of human mammary epithelial cells to DNA damage induced by 4-hydroxyequilenin: Lack of p53-mediated G1 arrest.
    Cuendet M, Bolton JL.
    Chem Biol Interact; 2006 Jul 10; 161(3):271-8. PubMed ID: 16730688
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  • 18. Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.
    Bogaards JJ, Venekamp JC, van Bladeren PJ.
    Chem Res Toxicol; 1997 Mar 10; 10(3):310-7. PubMed ID: 9084911
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