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Journal Abstract Search

405 related items for PubMed ID: 12119606

  • 1. Drug discovery by dynamic combinatorial libraries.
    Ramström O, Lehn JM.
    Nat Rev Drug Discov; 2002 Jan; 1(1):26-36. PubMed ID: 12119606
    [Abstract] [Full Text] [Related]

  • 2. Receptor-assisted combinatorial chemistry: thermodynamics and kinetics in drug discovery.
    Cheeseman JD, Corbett AD, Gleason JL, Kazlauskas RJ.
    Chemistry; 2005 Mar 04; 11(6):1708-16. PubMed ID: 15565741
    [Abstract] [Full Text] [Related]

  • 3. Dynamic combinatorial carbohydrate libraries: probing the binding site of the concanavalin A lectin.
    Ramström O, Lohmann S, Bunyapaiboonsri T, Lehn JM.
    Chemistry; 2004 Apr 02; 10(7):1711-5. PubMed ID: 15054758
    [Abstract] [Full Text] [Related]

  • 4. Chemical biology of dynamic combinatorial libraries.
    Ramström O, Bunyapaiboonsri T, Lohmann S, Lehn JM.
    Biochim Biophys Acta; 2002 Sep 19; 1572(2-3):178-86. PubMed ID: 12223268
    [Abstract] [Full Text] [Related]

  • 5. Dynamic mixtures and combinatorial libraries: imines as probes for molecular evolution at the interface between chemistry and biology.
    Herrmann A.
    Org Biomol Chem; 2009 Aug 21; 7(16):3195-204. PubMed ID: 19641772
    [Abstract] [Full Text] [Related]

  • 6. Emerging chemical and biological approaches for the preparation of discovery libraries.
    Boldt GE, Dickerson TJ, Janda KD.
    Drug Discov Today; 2006 Feb 21; 11(3-4):143-8. PubMed ID: 16533712
    [Abstract] [Full Text] [Related]

  • 7. Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis.
    Poulsen SA, Bornaghi LF.
    Bioorg Med Chem; 2006 May 15; 14(10):3275-84. PubMed ID: 16431113
    [Abstract] [Full Text] [Related]

  • 8. Design of diversity and focused combinatorial libraries in drug discovery.
    Young SS, Ge N.
    Curr Opin Drug Discov Devel; 2004 May 15; 7(3):318-24. PubMed ID: 15216935
    [Abstract] [Full Text] [Related]

  • 9. Application of combinatorial library methods in cancer research and drug discovery.
    Lam KS.
    Anticancer Drug Des; 1997 Apr 15; 12(3):145-67. PubMed ID: 9154108
    [Abstract] [Full Text] [Related]

  • 10. Dynamic combinatorial chemistry with hydrazones: cholate-based building blocks and libraries.
    Simpson MG, Pittelkow M, Watson SP, Sanders JK.
    Org Biomol Chem; 2010 Mar 07; 8(5):1173-80. PubMed ID: 20165810
    [Abstract] [Full Text] [Related]

  • 11. Methods for combinatorial and parallel library design.
    Schnur DM, Beno BR, Tebben AJ, Cavallaro C.
    Methods Mol Biol; 2011 Mar 07; 672():387-434. PubMed ID: 20838978
    [Abstract] [Full Text] [Related]

  • 12. Adaptive combinatorial design of focused compound libraries.
    Schneider G, Schüller A.
    Methods Mol Biol; 2009 Mar 07; 572():135-47. PubMed ID: 20694689
    [Abstract] [Full Text] [Related]

  • 13. Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds.
    Nefzi A, Ostresh JM, Yu Y, Houghten RA.
    J Org Chem; 2004 May 28; 69(11):3603-9. PubMed ID: 15152987
    [Abstract] [Full Text] [Related]

  • 14. Structure-based generation of viable leads from small combinatorial libraries.
    Laird ER, Blake JF.
    Curr Opin Drug Discov Devel; 2004 May 28; 7(3):354-9. PubMed ID: 15216940
    [Abstract] [Full Text] [Related]

  • 15. The impact of combinatorial chemistry on drug discovery.
    Lee A, Breitenbucher JG.
    Curr Opin Drug Discov Devel; 2003 Jul 28; 6(4):494-508. PubMed ID: 12951813
    [Abstract] [Full Text] [Related]

  • 16. The synergy between combinatorial chemistry and high-throughput screening.
    Diller DJ.
    Curr Opin Drug Discov Devel; 2008 May 28; 11(3):346-55. PubMed ID: 18428088
    [Abstract] [Full Text] [Related]

  • 17. Computational chemistry-driven decision making in lead generation.
    Schnecke V, Boström J.
    Drug Discov Today; 2006 Jan 28; 11(1-2):43-50. PubMed ID: 16478690
    [Abstract] [Full Text] [Related]

  • 18. Resin-bound dynamic combinatorial chemistry.
    McNaughton BR, Miller BL.
    Org Lett; 2006 Apr 27; 8(9):1803-6. PubMed ID: 16623555
    [Abstract] [Full Text] [Related]

  • 19. DNA-encoded chemical libraries.
    Scheuermann J, Dumelin CE, Melkko S, Neri D.
    J Biotechnol; 2006 Dec 01; 126(4):568-81. PubMed ID: 16860425
    [Abstract] [Full Text] [Related]

  • 20. Design and combinatorial synthesis of a novel kinase-focused library using click chemistry-based fragment assembly.
    Irie T, Fujii I, Sawa M.
    Bioorg Med Chem Lett; 2012 Jan 01; 22(1):591-6. PubMed ID: 22104147
    [Abstract] [Full Text] [Related]

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