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Journal Abstract Search
435 related items for PubMed ID: 12121969
1. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. MacFarlane M, Merrison W, Bratton SB, Cohen GM. J Biol Chem; 2002 Sep 27; 277(39):36611-6. PubMed ID: 12121969 [Abstract] [Full Text] [Related]
2. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Ng CP, Bonavida B. Mol Cancer Ther; 2002 Oct 27; 1(12):1051-8. PubMed ID: 12481428 [Abstract] [Full Text] [Related]
4. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Cancer Res; 2001 Oct 01; 61(19):7339-48. PubMed ID: 11585775 [Abstract] [Full Text] [Related]
5. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation. Hamacher-Brady A, Brady NR. J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559 [Abstract] [Full Text] [Related]
7. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES. J Biol Chem; 2000 Nov 17; 275(46):36152-7. PubMed ID: 10950947 [Abstract] [Full Text] [Related]
10. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells. Roa WH, Chen H, Fulton D, Gulavita S, Shaw A, Th'ng J, Farr-Jones M, Moore R, Petruk K. Clin Invest Med; 2003 Oct 17; 26(5):231-42. PubMed ID: 14596484 [Abstract] [Full Text] [Related]
11. Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis. Yoon K, Jang HD, Lee SY. Biochem Biophys Res Commun; 2004 Jun 25; 319(2):649-54. PubMed ID: 15178455 [Abstract] [Full Text] [Related]
12. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria. Zhang XD, Borrow JM, Zhang XY, Nguyen T, Hersey P. Oncogene; 2003 May 15; 22(19):2869-81. PubMed ID: 12771938 [Abstract] [Full Text] [Related]
13. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation. Rosato RR, Dai Y, Almenara JA, Maggio SC, Grant S. Leukemia; 2004 Nov 15; 18(11):1780-8. PubMed ID: 15385934 [Abstract] [Full Text] [Related]
14. Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis. Silke J, Kratina T, Ekert PG, Pakusch M, Vaux DL. J Biol Chem; 2004 Feb 06; 279(6):4313-21. PubMed ID: 14570909 [Abstract] [Full Text] [Related]
16. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Suzuki Y, Nakabayashi Y, Takahashi R. Proc Natl Acad Sci U S A; 2001 Jul 17; 98(15):8662-7. PubMed ID: 11447297 [Abstract] [Full Text] [Related]