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125 related items for PubMed ID: 12127687

  • 1. N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat.
    Satake N, Miyagawa M, Sakurai J, Mitani H, Kobayashi T, Tamura H, Hino O.
    Cancer Lett; 2002 Oct 28; 184(2):157-63. PubMed ID: 12127687
    [Abstract] [Full Text] [Related]

  • 2. Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell.
    Urakami S, Tokuzen R, Tsuda H, Igawa M, Hino O.
    J Urol; 1997 Jul 28; 158(1):275-8. PubMed ID: 9186374
    [Abstract] [Full Text] [Related]

  • 3. Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carcinoma.
    Satake N, Urakami S, Hirayama Y, Izumi K, Hino O.
    Int J Cancer; 1998 Sep 11; 77(6):895-900. PubMed ID: 9714060
    [Abstract] [Full Text] [Related]

  • 4. Specific induction of hepatocellular adenomas by transplacental administration of ENU in the tsc2 gene mutant (Eker) rat.
    Fukuda T, Mitani H, Tsutsumi M, Konishi Y, Hino O.
    Int J Oncol; 1998 Nov 11; 13(5):957-61. PubMed ID: 9772285
    [Abstract] [Full Text] [Related]

  • 5. Sequential observations on the appearance of neoplastic lesions in the liver and kidney after treatment with N-ethyl-N-hydroxyethylnitrosamine followed by partial hepatectomy and unilateral nephrectomy.
    Tsuda H, Sakata T, Tamano S, Okumura M, Ito N.
    Carcinogenesis; 1983 Nov 11; 4(5):523-8. PubMed ID: 6850982
    [Abstract] [Full Text] [Related]

  • 6. Specific genomic alterations in rat renal cell carcinomas induced by N-ethyl-N-hydroxyethylnitrosamine.
    Konishi N, Nakamura M, Ishida E, Kawada Y, Nishimine M, Nagai H, Emi M.
    Toxicol Pathol; 2001 Nov 11; 29(2):232-6. PubMed ID: 11421490
    [Abstract] [Full Text] [Related]

  • 7. Development of high-grade renal cell carcinomas in rats independently of somatic mutations in the Tsc2 and VHL tumor suppressor genes.
    Toyokuni S, Okada K, Kondo S, Nishioka H, Tanaka T, Nishiyama Y, Hino O, Hiai H.
    Jpn J Cancer Res; 1998 Aug 11; 89(8):814-20. PubMed ID: 9765616
    [Abstract] [Full Text] [Related]

  • 8. Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene.
    Kobayashi T, Mitani H, Takahashi R, Hirabayashi M, Ueda M, Tamura H, Hino O.
    Proc Natl Acad Sci U S A; 1997 Apr 15; 94(8):3990-3. PubMed ID: 9108092
    [Abstract] [Full Text] [Related]

  • 9. Modification of hepato- and renal carcinogenesis by catechol and its isomers in rats pretreated with N-ethyl-N-hydroxyethylnitrosamine.
    Okazaki S, Hoshiya T, Takahashi S, Futakuchi M, Saito K, Hirose M.
    Teratog Carcinog Mutagen; 1993 Apr 15; 13(3):127-37. PubMed ID: 7692615
    [Abstract] [Full Text] [Related]

  • 10. Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats.
    Takashima K, Ozono S, Nakanou I, Ota M, Tanaka M, Tani M, Hirao K, Hirao Y, Kuwashima S, Hiasa Y.
    Cancer Lett; 2001 Sep 20; 170(2):125-30. PubMed ID: 11463489
    [Abstract] [Full Text] [Related]

  • 11. Histopathological studies on renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
    Hiasa Y, Ohshima M, Iwata C, Tanikake T.
    Gan; 1979 Dec 20; 70(6):817-20. PubMed ID: 231537
    [Abstract] [Full Text] [Related]

  • 12. Basic lead acetate: promoting effect on the development of renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
    Hiasa Y, Ohshima M, Kitahori Y, Fujita T, Yuasa T, Miyashiro A.
    J Natl Cancer Inst; 1983 Apr 20; 70(4):761-5. PubMed ID: 6572762
    [Abstract] [Full Text] [Related]

  • 13. Initiation-stage enhancement by uracil of N-ethyl-N-hydroxyethylnitrosamine-induction of kidney carcinogenesis in rats.
    Takashi M, Sakata T, Nakano Y, Takagi Y, Yamada Y, Hibi H, Miyake K, Shirai T.
    Cancer Lett; 1994 Dec 09; 87(2):151-7. PubMed ID: 7812934
    [Abstract] [Full Text] [Related]

  • 14. Effect of methimazole on rat renal carcinogenesis induced by N-ethyl-N-hydroxyethylnitrosamine.
    Konishi N, Kitamura M, Hayashi I, Matsuda H, Tao M, Naitoh H, Kitahori Y, Hiasa Y.
    Toxicol Pathol; 1995 Dec 09; 23(5):606-11. PubMed ID: 8578103
    [Abstract] [Full Text] [Related]

  • 15. Distribution of Tsc2 protein in various normal rat tissues and renal tumours of Tsc2 mutant (Eker) rat detected by immunohistochemistry.
    Fukuda T, Kobayashi T, Yasui H, Tsutsumi M, Konishi Y, Hino O.
    Virchows Arch; 1999 Apr 09; 434(4):341-50. PubMed ID: 10335945
    [Abstract] [Full Text] [Related]

  • 16. Effect of polyphenon-60 on the development of renal cell tumors in rats treated with N-ethyl-N hydroxyethylnitrosamine.
    Yoshioka N, Hiasa Y, Cho M, Kitahori Y, Hirao K, Konishi N, Kuwashima S.
    Cancer Lett; 1999 Feb 08; 136(1):79-82. PubMed ID: 10211943
    [Abstract] [Full Text] [Related]

  • 17. Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine.
    Tsuda H, Sakata T, Masui T, Imaida K, Ito N.
    Carcinogenesis; 1984 Apr 08; 5(4):525-31. PubMed ID: 6142774
    [Abstract] [Full Text] [Related]

  • 18. Formation of 8-hydroxydeoxyguanosine in rat kidney DNA after administration of N-ethyl-N-hydroxyethylnitrosamine.
    Sato M, Kitahori Y, Nakagawa Y, Konishi N, Cho M, Hiasa Y.
    Cancer Lett; 1998 Feb 13; 124(1):111-8. PubMed ID: 9500199
    [Abstract] [Full Text] [Related]

  • 19. Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model.
    Kobayashi T, Urakami S, Hirayama Y, Yamamoto T, Nishizawa M, Takahara T, Kubo Y, Hino O.
    Jpn J Cancer Res; 1997 Mar 13; 88(3):254-61. PubMed ID: 9140109
    [Abstract] [Full Text] [Related]

  • 20. Experimental model of renal tumors in polycystic kidneys: effects of long-term 2-amino-4,5-diphenylthiazole administration in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
    Tsumatani K, Nakagawa Y, Kitahori Y, Konishi N, Uemura H, Ozono S, Hirao Y, Okajima E, Hirao K, Hiasa Y.
    Toxicol Pathol; 1997 Mar 13; 25(4):363-71. PubMed ID: 9280119
    [Abstract] [Full Text] [Related]


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