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144 related items for PubMed ID: 12130656

  • 1. Carbamoyl-phosphate synthetase. Creation of an escape route for ammonia.
    Thoden JB, Huang X, Raushel FM, Holden HM.
    J Biol Chem; 2002 Oct 18; 277(42):39722-7. PubMed ID: 12130656
    [Abstract] [Full Text] [Related]

  • 2. The amidotransferase family of enzymes: molecular machines for the production and delivery of ammonia.
    Raushel FM, Thoden JB, Holden HM.
    Biochemistry; 1999 Jun 22; 38(25):7891-9. PubMed ID: 10387030
    [Abstract] [Full Text] [Related]

  • 3. An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
    Huang X, Raushel FM.
    Biochemistry; 2000 Mar 28; 39(12):3240-7. PubMed ID: 10727215
    [Abstract] [Full Text] [Related]

  • 4. Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis.
    Thoden JB, Miran SG, Phillips JC, Howard AJ, Raushel FM, Holden HM.
    Biochemistry; 1998 Jun 23; 37(25):8825-31. PubMed ID: 9636022
    [Abstract] [Full Text] [Related]

  • 5. Perforation of the tunnel wall in carbamoyl phosphate synthetase derails the passage of ammonia between sequential active sites.
    Kim J, Raushel FM.
    Biochemistry; 2004 May 11; 43(18):5334-40. PubMed ID: 15122899
    [Abstract] [Full Text] [Related]

  • 6. A combined theoretical and experimental study of the ammonia tunnel in carbamoyl phosphate synthetase.
    Fan Y, Lund L, Shao Q, Gao YQ, Raushel FM.
    J Am Chem Soc; 2009 Jul 29; 131(29):10211-9. PubMed ID: 19569682
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of carbamoyl phosphate synthetase from Escherichia coli--binding of the ATP molecules used in the reaction and sequestration by the enzyme of the ATP molecule that yields carbamoyl phosphate.
    Rubio V, Llorente P, Britton HG.
    Eur J Biochem; 1998 Jul 01; 255(1):262-70. PubMed ID: 9692927
    [Abstract] [Full Text] [Related]

  • 8. Long-range allosteric transitions in carbamoyl phosphate synthetase.
    Thoden JB, Huang X, Kim J, Raushel FM, Holden HM.
    Protein Sci; 2004 Sep 01; 13(9):2398-405. PubMed ID: 15322282
    [Abstract] [Full Text] [Related]

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  • 10. Restricted passage of reaction intermediates through the ammonia tunnel of carbamoyl phosphate synthetase.
    Huang X, Raushel FM.
    J Biol Chem; 2000 Aug 25; 275(34):26233-40. PubMed ID: 10950966
    [Abstract] [Full Text] [Related]

  • 11. Carbamoyl phosphate synthetase: a crooked path from substrates to products.
    Raushel FM, Thoden JB, Reinhart GD, Holden HM.
    Curr Opin Chem Biol; 1998 Oct 25; 2(5):624-32. PubMed ID: 9818189
    [Abstract] [Full Text] [Related]

  • 12. A stringent test for the nucleotide switch mechanism of carbamoyl phosphate synthetase.
    Raushel FM, Mullins LS, Gibson GE.
    Biochemistry; 1998 Jul 14; 37(28):10272-8. PubMed ID: 9665735
    [Abstract] [Full Text] [Related]

  • 13. Comparison of the functional differences for the homologous residues within the carboxy phosphate and carbamate domains of carbamoyl phosphate synthetase.
    Javid-Majd F, Stapleton MA, Harmon MF, Hanks BA, Mullins LS, Raushel FM.
    Biochemistry; 1996 Nov 12; 35(45):14362-9. PubMed ID: 8916923
    [Abstract] [Full Text] [Related]

  • 14. The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution.
    Thoden JB, Raushel FM, Benning MM, Rayment I, Holden HM.
    Acta Crystallogr D Biol Crystallogr; 1999 Jan 12; 55(Pt 1):8-24. PubMed ID: 10089390
    [Abstract] [Full Text] [Related]

  • 15. Structure of carbamoyl phosphate synthetase: a journey of 96 A from substrate to product.
    Thoden JB, Holden HM, Wesenberg G, Raushel FM, Rayment I.
    Biochemistry; 1997 May 27; 36(21):6305-16. PubMed ID: 9174345
    [Abstract] [Full Text] [Related]

  • 16. Synchronization of the three reaction centers within carbamoyl phosphate synthetase.
    Miles BW, Raushel FM.
    Biochemistry; 2000 May 02; 39(17):5051-6. PubMed ID: 10819970
    [Abstract] [Full Text] [Related]

  • 17. Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding.
    Thoden JB, Wesenberg G, Raushel FM, Holden HM.
    Biochemistry; 1999 Feb 23; 38(8):2347-57. PubMed ID: 10029528
    [Abstract] [Full Text] [Related]

  • 18. Regulatory changes in the control of carbamoyl phosphate synthetase induced by truncation and mutagenesis of the allosteric binding domain.
    Czerwinski RM, Mareya SM, Raushel FM.
    Biochemistry; 1995 Oct 24; 34(42):13920-7. PubMed ID: 7577987
    [Abstract] [Full Text] [Related]

  • 19. Specificity determining residues in ammonia- and glutamine-dependent carbamoyl phosphate synthetases.
    Saeed-Kothe A, Powers-Lee SG.
    J Biol Chem; 2002 Mar 01; 277(9):7231-8. PubMed ID: 11756425
    [Abstract] [Full Text] [Related]

  • 20. Catalytic domains of carbamyl phosphate synthetase. Glutamine-hydrolyzing site of Escherichia coli carbamyl phosphate synthetase.
    Rubino SD, Nyunoya H, Lusty CJ.
    J Biol Chem; 1986 Aug 25; 261(24):11320-7. PubMed ID: 3525565
    [Abstract] [Full Text] [Related]

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