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161 related items for PubMed ID: 12149149

  • 1. Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.
    Shimamoto Y, Koizumi K, Okabe H, Kazuno H, Murakami Y, Nakagawa F, Matsuda A, Sasaki T, Fukushima M.
    Jpn J Cancer Res; 2002 Jul; 93(7):825-33. PubMed ID: 12149149
    [Abstract] [Full Text] [Related]

  • 2. Cellular and biochemical mechanisms of the resistance of human cancer cells to a new anticancer ribo-nucleoside, TAS-106.
    Shimamoto Y, Kazuno H, Murakami Y, Azuma A, Koizumi K, Matsuda A, Sasaki T, Fukushima M.
    Jpn J Cancer Res; 2002 Apr; 93(4):445-52. PubMed ID: 11985795
    [Abstract] [Full Text] [Related]

  • 3. A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides.
    Murata D, Endo Y, Obata T, Sakamoto K, Syouji Y, Kadohira M, Matsuda A, Sasaki T.
    Drug Metab Dispos; 2004 Oct; 32(10):1178-82. PubMed ID: 15280220
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  • 4. The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.
    van Kuilenburg AB, Meinsma R.
    Biochim Biophys Acta; 2016 Sep; 1862(9):1504-12. PubMed ID: 27239701
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  • 5. The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.
    Sarkisjan D, Julsing JR, Smid K, de Klerk D, van Kuilenburg AB, Meinsma R, Lee YB, Kim DJ, Peters GJ.
    PLoS One; 2016 Sep; 11(9):e0162901. PubMed ID: 27612203
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  • 6. Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.
    Meinsma R, van Kuilenburg AB.
    Nucleosides Nucleotides Nucleic Acids; 2016 Dec; 35(10-12):613-618. PubMed ID: 27906629
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  • 10. Antitumor mechanisms and metabolism of the novel antitumor nucleoside analogues, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil.
    Takatori S, Kanda H, Takenaka K, Wataya Y, Matsuda A, Fukushima M, Shimamoto Y, Tanaka M, Sasaki T.
    Cancer Chemother Pharmacol; 1999 Dec; 44(2):97-104. PubMed ID: 10412942
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  • 11. Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.
    Kazuno H, Shimamoto Y, Tsujimoto H, Fukushima M, Matsuda A, Sasaki T.
    Oncol Rep; 2007 Jun; 17(6):1453-60. PubMed ID: 17487404
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  • 12. Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.
    Van Rompay AR, Norda A, Lindén K, Johansson M, Karlsson A.
    Mol Pharmacol; 2001 May; 59(5):1181-6. PubMed ID: 11306702
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  • 13. Phosphorylation of uridine and cytidine by uridine-cytidine kinase.
    Qian Y, Ding Q, Li Y, Zou Z, Yan B, Ou L.
    J Biotechnol; 2014 Oct 20; 188():81-7. PubMed ID: 25160914
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  • 14. Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activity.
    Hattori H, Tanaka M, Fukushima M, Sasaki T, Matsuda A.
    J Med Chem; 1996 Dec 06; 39(25):5005-11. PubMed ID: 8960561
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  • 15. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106)1: antitumor effect and mechanism of action.
    Azuma A, Matsuda A, Sasaki T, Fukushima M.
    Nucleosides Nucleotides Nucleic Acids; 2001 Dec 06; 20(4-7):609-19. PubMed ID: 11563078
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  • 16. Antitumor activity and pharmacokinetics of TAS-106, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.
    Shimamoto Y, Fujioka A, Kazuno H, Murakami Y, Ohshimo H, Kato T, Matsuda A, Sasaki T, Fukushima M.
    Jpn J Cancer Res; 2001 Mar 06; 92(3):343-51. PubMed ID: 11267946
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  • 17. 1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.
    Kazuno H, Fujioka A, Fukushima M, Wataya Y, Matsuda A, Sasaki T.
    Int J Oncol; 2009 May 06; 34(5):1373-80. PubMed ID: 19360349
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  • 18. Synthesis and biologic study of IV-14, a new ribonucleoside radiotracer for tumor visualization.
    Zlatopolskiy BD, Morgenroth A, Kunkel FH, Urusova EA, Dinger C, Kull T, Lepping C, Reske SN.
    J Nucl Med; 2009 Nov 06; 50(11):1895-903. PubMed ID: 19837748
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  • 19. Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells.
    Koizumi K, Shimamoto Y, Azuma A, Wataya Y, Matsuda A, Sasaki T, Fukushima M.
    Int J Mol Med; 2001 Sep 06; 8(3):273-8. PubMed ID: 11494055
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