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519 related items for PubMed ID: 12154034

  • 1. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.
    Chakravarti A, Chakladar A, Delaney MA, Latham DE, Loeffler JS.
    Cancer Res; 2002 Aug 01; 62(15):4307-15. PubMed ID: 12154034
    [Abstract] [Full Text] [Related]

  • 2. Bradykinin-induced p42/p44 MAPK phosphorylation and cell proliferation via Src, EGF receptors, and PI3-K/Akt in vascular smooth muscle cells.
    Yang CM, Lin MI, Hsieh HL, Sun CC, Ma YH, Hsiao LD.
    J Cell Physiol; 2005 Jun 01; 203(3):538-46. PubMed ID: 15573401
    [Abstract] [Full Text] [Related]

  • 3. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM, Rusyn EV, Zhou H, Sartor CI, Cox AD.
    Cancer Res; 2002 Jul 15; 62(14):4142-50. PubMed ID: 12124353
    [Abstract] [Full Text] [Related]

  • 4. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling.
    Chakravarti A, Loeffler JS, Dyson NJ.
    Cancer Res; 2002 Jan 01; 62(1):200-7. PubMed ID: 11782378
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs).
    Wu CJ, Chen Z, Ullrich A, Greene MI, O'Rourke DM.
    Oncogene; 2000 Aug 17; 19(35):3999-4010. PubMed ID: 10962556
    [Abstract] [Full Text] [Related]

  • 6. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
    Oncogene; 2004 Jan 08; 23(1):9-20. PubMed ID: 14712206
    [Abstract] [Full Text] [Related]

  • 7. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M, Morelli C, Mauro L, Andò S, Surmacz E.
    Cancer Res; 2001 Sep 15; 61(18):6747-54. PubMed ID: 11559546
    [Abstract] [Full Text] [Related]

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  • 9. Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
    Li B, Chang CM, Yuan M, McKenna WG, Shu HK.
    Cancer Res; 2003 Nov 01; 63(21):7443-50. PubMed ID: 14612544
    [Abstract] [Full Text] [Related]

  • 10. Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme.
    Liu KJ, Chen CT, Hu WS, Hung YM, Hsu CY, Chuang BF, Juang SH.
    Int J Oncol; 2004 Mar 01; 24(3):581-90. PubMed ID: 14767543
    [Abstract] [Full Text] [Related]

  • 11. Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells.
    Hassan S, Dobner PR, Carraway RE.
    Regul Pept; 2004 Aug 15; 120(1-3):155-66. PubMed ID: 15177934
    [Abstract] [Full Text] [Related]

  • 12. Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.
    Maity A, Pore N, Lee J, Solomon D, O'Rourke DM.
    Cancer Res; 2000 Oct 15; 60(20):5879-86. PubMed ID: 11059786
    [Abstract] [Full Text] [Related]

  • 13. Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity.
    Toulany M, Baumann M, Rodemann HP.
    Mol Cancer Res; 2007 Aug 15; 5(8):863-72. PubMed ID: 17699110
    [Abstract] [Full Text] [Related]

  • 14. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV, Reynolds ER, Shao H, Grana TM, Chan TO, Andres DA, Cox AD.
    Oncogene; 2000 Sep 28; 19(41):4685-94. PubMed ID: 11032018
    [Abstract] [Full Text] [Related]

  • 15. H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells.
    Zhuang S, Schnellmann RG.
    Am J Physiol Renal Physiol; 2004 May 28; 286(5):F858-65. PubMed ID: 15075181
    [Abstract] [Full Text] [Related]

  • 16. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.
    Narita Y, Nagane M, Mishima K, Huang HJ, Furnari FB, Cavenee WK.
    Cancer Res; 2002 Nov 15; 62(22):6764-9. PubMed ID: 12438278
    [Abstract] [Full Text] [Related]

  • 17. Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways.
    Xia W, Mullin RJ, Keith BR, Liu LH, Ma H, Rusnak DW, Owens G, Alligood KJ, Spector NL.
    Oncogene; 2002 Sep 12; 21(41):6255-63. PubMed ID: 12214266
    [Abstract] [Full Text] [Related]

  • 18. Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis.
    Eckert LB, Repasky GA, Ulkü AS, McFall A, Zhou H, Sartor CI, Der CJ.
    Cancer Res; 2004 Jul 01; 64(13):4585-92. PubMed ID: 15231670
    [Abstract] [Full Text] [Related]

  • 19. The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6.
    Kuo ML, Chuang SE, Lin MT, Yang SY.
    Oncogene; 2001 Feb 08; 20(6):677-85. PubMed ID: 11314001
    [Abstract] [Full Text] [Related]

  • 20. EGFRvIII-mediated radioresistance through a strong cytoprotective response.
    Lammering G, Hewit TH, Valerie K, Contessa JN, Amorino GP, Dent P, Schmidt-Ullrich RK.
    Oncogene; 2003 Aug 28; 22(36):5545-53. PubMed ID: 12944901
    [Abstract] [Full Text] [Related]

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