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148 related items for PubMed ID: 12161256

  • 1. Effect of the free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats.
    Ikeda T, Xia YX, Kaneko M, Sameshima H, Ikenoue T.
    Neurosci Lett; 2002 Aug 23; 329(1):33-6. PubMed ID: 12161256
    [Abstract] [Full Text] [Related]

  • 2. Short-term administration of a new free radical scavenger, edaravone, is more effective than its long-term administration for the treatment of neonatal hypoxic-ischemic encephalopathy.
    Noor JI, Ikeda T, Mishima K, Aoo N, Ohta S, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T.
    Stroke; 2005 Nov 23; 36(11):2468-74. PubMed ID: 16210562
    [Abstract] [Full Text] [Related]

  • 3. Edaravone inhibits lipid peroxidation in neonatal hypoxic-ischemic rats: an in vivo microdialysis study.
    Noor JI, Ueda Y, Ikeda T, Ikenoue T.
    Neurosci Lett; 2007 Feb 27; 414(1):5-9. PubMed ID: 17280782
    [Abstract] [Full Text] [Related]

  • 4. Gene network analysis to determine the effects of antioxidant treatment in a rat model of neonatal hypoxic-ischemic encephalopathy.
    Kojima T, Ueda Y, Adati N, Kitamoto A, Sato A, Huang MC, Noor J, Sameshima H, Ikenoue T.
    J Mol Neurosci; 2010 Oct 27; 42(2):154-61. PubMed ID: 20191329
    [Abstract] [Full Text] [Related]

  • 5. A free radical scavenger, edaravone, inhibits lipid peroxidation and the production of nitric oxide in hypoxic-ischemic brain damage of neonatal rats.
    Noor JI, Ikeda T, Ueda Y, Ikenoue T.
    Am J Obstet Gynecol; 2005 Nov 27; 193(5):1703-8. PubMed ID: 16260214
    [Abstract] [Full Text] [Related]

  • 6. Striatal neuroprotection from neonatal hypoxia-ischemia in piglets by antioxidant treatment with EUK-134 or edaravone.
    Ni X, Yang ZJ, Carter EL, Martin LJ, Koehler RC.
    Dev Neurosci; 2011 Nov 27; 33(3-4):299-311. PubMed ID: 21701140
    [Abstract] [Full Text] [Related]

  • 7. Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion.
    Mizuno A, Umemura K, Nakashima M.
    Gen Pharmacol; 1998 Apr 27; 30(4):575-8. PubMed ID: 9522178
    [Abstract] [Full Text] [Related]

  • 8. [Research and development of the free radical scavenger edaravone as a neuroprotectant].
    Watanabe T, Tanaka M, Watanabe K, Takamatsu Y, Tobe A.
    Yakugaku Zasshi; 2004 Mar 27; 124(3):99-111. PubMed ID: 15049127
    [Abstract] [Full Text] [Related]

  • 9. Edaravone protects against ischemia/reperfusion-induced oxidative damage to mitochondria in rat liver.
    Okatani Y, Wakatsuki A, Enzan H, Miyahara Y.
    Eur J Pharmacol; 2003 Mar 28; 465(1-2):163-70. PubMed ID: 12650846
    [Abstract] [Full Text] [Related]

  • 10. Maternal treatment with MCI-186 does not improve delayed deterioration of cellular bioenergetic state and mitochondrial activity following transient intrauterine ischemia in the fetal rat brain.
    Yokota A, Nakai A, Taniuchi Y, Okuda N, Nakai M, Takeshita T.
    J Nippon Med Sch; 2005 Apr 28; 72(2):127-30. PubMed ID: 15940021
    [Abstract] [Full Text] [Related]

  • 11. Structure-activity relationship of 3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone).
    Watanabe K, Morinaka Y, Iseki K, Watanabe T, Yuki S, Nishi H.
    Redox Rep; 2003 Apr 28; 8(3):151-5. PubMed ID: 12935312
    [Abstract] [Full Text] [Related]

  • 12. Repeated edaravone treatment reduces oxidative cell damage in rat brain induced by middle cerebral artery occlusion.
    Yamamoto Y, Yanagisawa M, Tak NW, Watanabe K, Takahashi C, Fujisawa A, Kashiba M, Tanaka M.
    Redox Rep; 2009 Apr 28; 14(6):251-8. PubMed ID: 20003710
    [Abstract] [Full Text] [Related]

  • 13. Edaravone inhibits DNA peroxidation and neuronal cell death in neonatal hypoxic-ischemic encephalopathy model rat.
    Takizawa Y, Miyazawa T, Nonoyama S, Goto Y, Itoh M.
    Pediatr Res; 2009 Jun 28; 65(6):636-41. PubMed ID: 19247215
    [Abstract] [Full Text] [Related]

  • 14. [Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent].
    Tanaka M.
    Nihon Yakurigaku Zasshi; 2002 May 28; 119(5):301-8. PubMed ID: 12061142
    [Abstract] [Full Text] [Related]

  • 15. Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.
    Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.
    J Pharmacol Exp Ther; 2009 May 28; 329(2):687-98. PubMed ID: 19201991
    [Abstract] [Full Text] [Related]

  • 16. Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney.
    Doi K, Suzuki Y, Nakao A, Fujita T, Noiri E.
    Kidney Int; 2004 May 28; 65(5):1714-23. PubMed ID: 15086910
    [Abstract] [Full Text] [Related]

  • 17. Antioxidant effect of MCI-186, a new Free-Radical scavenger, on ischemia-reperfusion injury in a rat hindlimb amputation model.
    Irie H, Kato T, Ikebe K, Tsuchida T, Oniki Y, Takagi K.
    J Surg Res; 2004 Aug 28; 120(2):312-9. PubMed ID: 15234228
    [Abstract] [Full Text] [Related]

  • 18. Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat.
    Nakashima M, Niwa M, Iwai T, Uematsu T.
    Free Radic Biol Med; 1999 Mar 28; 26(5-6):722-9. PubMed ID: 10218662
    [Abstract] [Full Text] [Related]

  • 19. MCI-186: further histochemical and biochemical evidence of neuroprotection.
    Wu TW, Zeng LH, Wu J, Fung KP.
    Life Sci; 2000 Sep 29; 67(19):2387-92. PubMed ID: 11065185
    [Abstract] [Full Text] [Related]

  • 20. The changes of LCGU and rCBF in the MCA occlusion-recirculation model in rats and the ameliorating effect of MCI-186, a novel free radical scavenger.
    Yuki S, Kogure K.
    Mol Chem Neuropathol; 1997 Sep 29; 32(1-3):123-8. PubMed ID: 9437662
    [Abstract] [Full Text] [Related]

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