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223 related items for PubMed ID: 12165555

  • 1. Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects.
    Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM.
    Hum Mol Genet; 2002 Aug 15; 11(17):1927-37. PubMed ID: 12165555
    [Abstract] [Full Text] [Related]

  • 2. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.
    Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM.
    Hum Mol Genet; 2002 Aug 15; 11(17):1939-51. PubMed ID: 12165556
    [Abstract] [Full Text] [Related]

  • 3. Polyglutamine pathogenesis.
    Ross CA, Wood JD, Schilling G, Peters MF, Nucifora FC, Cooper JK, Sharp AH, Margolis RL, Borchelt DR.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1005-11. PubMed ID: 10434299
    [Abstract] [Full Text] [Related]

  • 4. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain.
    Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, Peters NL, Woods AM, Chan EY, Kooperberg C, Krainc D, Young AB, Tapscott SJ, Olson JM.
    Hum Mol Genet; 2002 Aug 15; 11(17):1911-26. PubMed ID: 12165554
    [Abstract] [Full Text] [Related]

  • 5. FAT10 protein binds to polyglutamine proteins and modulates their solubility.
    Nagashima Y, Kowa H, Tsuji S, Iwata A.
    J Biol Chem; 2011 Aug 26; 286(34):29594-600. PubMed ID: 21757738
    [Abstract] [Full Text] [Related]

  • 6. Targeting several CAG expansion diseases by a single antisense oligonucleotide.
    Evers MM, Pepers BA, van Deutekom JC, Mulders SA, den Dunnen JT, Aartsma-Rus A, van Ommen GJ, van Roon-Mom WM.
    PLoS One; 2011 Aug 26; 6(9):e24308. PubMed ID: 21909428
    [Abstract] [Full Text] [Related]

  • 7. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity.
    Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA.
    J Biol Chem; 2003 Apr 11; 278(15):13047-55. PubMed ID: 12464607
    [Abstract] [Full Text] [Related]

  • 8. Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy.
    Suzuki Y, Nakayama K, Hashimoto N, Yazawa I.
    FEBS J; 2010 Dec 11; 277(23):4873-87. PubMed ID: 20977674
    [Abstract] [Full Text] [Related]

  • 9. Increased aggregation of polyleucine compared with that of polyglutamine in dentatorubral-pallidoluysian atrophy protein.
    Suzuki Y, Jin C, Yazawa I.
    Neurosci Lett; 2013 Sep 27; 552():156-61. PubMed ID: 23933208
    [Abstract] [Full Text] [Related]

  • 10. Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.
    Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D.
    J Neurosci; 2004 Feb 25; 24(8):1881-7. PubMed ID: 14985428
    [Abstract] [Full Text] [Related]

  • 11. Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.
    Jin J, Cheng Y, Zhang Y, Wood W, Peng Q, Hutchison E, Mattson MP, Becker KG, Duan W.
    J Neurochem; 2012 Nov 25; 123(4):477-90. PubMed ID: 22906125
    [Abstract] [Full Text] [Related]

  • 12. SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death.
    Terashima T, Kawai H, Fujitani M, Maeda K, Yasuda H.
    Neuroreport; 2002 Dec 03; 13(17):2359-64. PubMed ID: 12488827
    [Abstract] [Full Text] [Related]

  • 13. Comparative analyses of Purkinje cell gene expression profiles reveal shared molecular abnormalities in models of different polyglutamine diseases.
    Friedrich B, Euler P, Ziegler R, Kuhn A, Landwehrmeyer BG, Luthi-Carter R, Weiller C, Hellwig S, Zucker B.
    Brain Res; 2012 Oct 24; 1481():37-48. PubMed ID: 22917585
    [Abstract] [Full Text] [Related]

  • 14. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.
    Jin J, Albertz J, Guo Z, Peng Q, Rudow G, Troncoso JC, Ross CA, Duan W.
    J Neurochem; 2013 May 24; 125(3):410-9. PubMed ID: 23373812
    [Abstract] [Full Text] [Related]

  • 15. Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.
    Lu Z, Marks E, Chen J, Moline J, Barrows L, Raisbeck M, Volitakis I, Cherny RA, Chopra V, Bush AI, Hersch S, Fox JH.
    Neurobiol Dis; 2014 Nov 24; 71():34-42. PubMed ID: 25014023
    [Abstract] [Full Text] [Related]

  • 16. Pathological accumulation of atrophin-1 in dentatorubralpallidoluysian atrophy.
    Suzuki Y, Yazawa I.
    Int J Clin Exp Pathol; 2011 Apr 24; 4(4):378-84. PubMed ID: 21577324
    [Abstract] [Full Text] [Related]

  • 17. Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs.
    Hu J, Liu J, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Swayze EE, Lima WF, Prakash TP, Xiang Q, Martinez C, Corey DR.
    Biochemistry; 2014 Jul 22; 53(28):4510-8. PubMed ID: 24981774
    [Abstract] [Full Text] [Related]

  • 18. Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice.
    Sato T, Miura M, Yamada M, Yoshida T, Wood JD, Yazawa I, Masuda M, Suzuki T, Shin RM, Yau HJ, Liu FC, Shimohata T, Onodera O, Ross CA, Katsuki M, Takahashi H, Kano M, Aosaki T, Tsuji S.
    Hum Mol Genet; 2009 Feb 15; 18(4):723-36. PubMed ID: 19039037
    [Abstract] [Full Text] [Related]

  • 19. Polyglutamine disease: recent advances in the neuropathology of dentatorubral-pallidoluysian atrophy.
    Yamada M, Shimohata M, Sato T, Tsuji S, Takahashi H.
    Neuropathology; 2006 Aug 15; 26(4):346-51. PubMed ID: 16961072
    [Abstract] [Full Text] [Related]

  • 20. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
    Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, Frey AS, Spektor BS, Penney EB, Schilling G, Ross CA, Borchelt DR, Tapscott SJ, Young AB, Cha JH, Olson JM.
    Hum Mol Genet; 2000 May 22; 9(9):1259-71. PubMed ID: 10814708
    [Abstract] [Full Text] [Related]

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