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179 related items for PubMed ID: 12165567

  • 1. Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease.
    Kirby J, Menzies FM, Cookson MR, Bushby K, Shaw PJ.
    Hum Mol Genet; 2002 Aug 15; 11(17):2061-75. PubMed ID: 12165567
    [Abstract] [Full Text] [Related]

  • 2. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
    Cookson MR, Menzies FM, Manning P, Eggett CJ, Figlewicz DA, McNeil CJ, Shaw PJ.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun 15; 3(2):75-85. PubMed ID: 12215229
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.
    Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L, Figlewicz DA, Shaw PJ.
    Brain; 2002 Jul 15; 125(Pt 7):1522-33. PubMed ID: 12077002
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  • 4. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.
    Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ.
    Brain; 2005 Jul 15; 128(Pt 7):1686-706. PubMed ID: 15872021
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  • 5. Cultured glial cells are resistant to the effects of motor neurone disease-associated SOD1 mutations.
    Williams RE, Cookson MR, Fray AE, Manning PM, Menzies FM, Figlewicz DA, Shaw PJ.
    Neurosci Lett; 2001 Apr 20; 302(2-3):146-50. PubMed ID: 11290408
    [Abstract] [Full Text] [Related]

  • 6. Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways.
    Allen S, Heath PR, Kirby J, Wharton SB, Cookson MR, Menzies FM, Banks RE, Shaw PJ.
    J Biol Chem; 2003 Feb 21; 278(8):6371-83. PubMed ID: 12475980
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  • 7. Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
    Tobisawa S, Hozumi Y, Arawaka S, Koyama S, Wada M, Nagai M, Aoki M, Itoyama Y, Goto K, Kato T.
    Biochem Biophys Res Commun; 2003 Apr 04; 303(2):496-503. PubMed ID: 12659845
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  • 8. Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
    Ferri A, Nencini M, Casciati A, Cozzolino M, Angelini DF, Longone P, Spalloni A, Rotilio G, Carrì MT.
    FASEB J; 2004 Aug 04; 18(11):1261-3. PubMed ID: 15208263
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  • 9. Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification.
    Watanabe Y, Yasui K, Nakano T, Doi K, Fukada Y, Kitayama M, Ishimoto M, Kurihara S, Kawashima M, Fukuda H, Adachi Y, Inoue T, Nakashima K.
    Brain Res Mol Brain Res; 2005 Apr 27; 135(1-2):12-20. PubMed ID: 15857664
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition.
    Sathasivam S, Grierson AJ, Shaw PJ.
    Neuropathol Appl Neurobiol; 2005 Oct 27; 31(5):467-85. PubMed ID: 16150118
    [Abstract] [Full Text] [Related]

  • 11. Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis.
    Menzies FM, Grierson AJ, Cookson MR, Heath PR, Tomkins J, Figlewicz DA, Ince PG, Shaw PJ.
    J Neurochem; 2002 Sep 27; 82(5):1118-28. PubMed ID: 12358759
    [Abstract] [Full Text] [Related]

  • 12. HoxB2 binds mutant SOD1 and is altered in transgenic model of ALS.
    Zhai J, Lin H, Canete-Soler R, Schlaepfer WW.
    Hum Mol Genet; 2005 Sep 15; 14(18):2629-40. PubMed ID: 16079151
    [Abstract] [Full Text] [Related]

  • 13. Oxidative stress and motor neurone disease.
    Cookson MR, Shaw PJ.
    Brain Pathol; 1999 Jan 15; 9(1):165-86. PubMed ID: 9989458
    [Abstract] [Full Text] [Related]

  • 14. Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2.
    Lee M, Hyun DH, Halliwell B, Jenner P.
    J Neurochem; 2001 Jul 15; 78(2):209-20. PubMed ID: 11461956
    [Abstract] [Full Text] [Related]

  • 15. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
    Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR.
    Neurobiol Dis; 2005 Dec 15; 20(3):943-52. PubMed ID: 16046140
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  • 20. Detection method of the adjacent motor neuronal death in an in vitro co-culture model of familial ALS-associated Cu/Zn superoxide dismutase.
    Park KS, Kim HJ, Choi WJ, Kim M, Lee KW.
    Biotechnol Lett; 2004 Aug 15; 26(15):1201-5. PubMed ID: 15289674
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