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263 related items for PubMed ID: 12167488

  • 1. Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.
    Kemp DM, Habener JF.
    Biochem Pharmacol; 2002 Aug 15; 64(4):689-97. PubMed ID: 12167488
    [Abstract] [Full Text] [Related]

  • 2. Insulinotropic hormone glucagon-like peptide 1 (GLP-1) activation of insulin gene promoter inhibited by p38 mitogen-activated protein kinase.
    Kemp DM, Habener JF.
    Endocrinology; 2001 Mar 15; 142(3):1179-87. PubMed ID: 11181533
    [Abstract] [Full Text] [Related]

  • 3. Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.
    Skoglund G, Hussain MA, Holz GG.
    Diabetes; 2000 Jul 15; 49(7):1156-64. PubMed ID: 10909973
    [Abstract] [Full Text] [Related]

  • 4. NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.
    Lawrence MC, Bhatt HS, Easom RA.
    Diabetes; 2002 Mar 15; 51(3):691-8. PubMed ID: 11872668
    [Abstract] [Full Text] [Related]

  • 5. Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site.
    Hay CW, Sinclair EM, Bermano G, Durward E, Tadayyon M, Docherty K.
    J Endocrinol; 2005 Aug 15; 186(2):353-65. PubMed ID: 16079261
    [Abstract] [Full Text] [Related]

  • 6. Ligand-induced regulation of glucagon-like peptide-I receptor function and expression in insulin-secreting beta cells.
    Fehmann HC, Jiang J, Pitt D, Schweinfurth J, Göke B.
    Pancreas; 1996 Oct 15; 13(3):273-82. PubMed ID: 8884849
    [Abstract] [Full Text] [Related]

  • 7. Mutations to the third cytoplasmic domain of the glucagon-like peptide 1 (GLP-1) receptor can functionally uncouple GLP-1-stimulated insulin secretion in HIT-T15 cells.
    Salapatek AM, MacDonald PE, Gaisano HY, Wheeler MB.
    Mol Endocrinol; 1999 Aug 15; 13(8):1305-17. PubMed ID: 10446905
    [Abstract] [Full Text] [Related]

  • 8. Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.
    Hussain MA, Daniel PB, Habener JF.
    Diabetes; 2000 Oct 15; 49(10):1681-90. PubMed ID: 11016452
    [Abstract] [Full Text] [Related]

  • 9. Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.
    Wang X, Zhou J, Doyle ME, Egan JM.
    Endocrinology; 2001 May 15; 142(5):1820-7. PubMed ID: 11316746
    [Abstract] [Full Text] [Related]

  • 10. Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor.
    Yusta B, Somwar R, Wang F, Munroe D, Grinstein S, Klip A, Drucker DJ.
    J Biol Chem; 1999 Oct 22; 274(43):30459-67. PubMed ID: 10521425
    [Abstract] [Full Text] [Related]

  • 11. Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells.
    Stark A, Mentlein R.
    Regul Pept; 2002 Oct 15; 108(2-3):97-102. PubMed ID: 12220732
    [Abstract] [Full Text] [Related]

  • 12. Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets.
    Laychock SG.
    Mol Cell Endocrinol; 1995 Aug 30; 113(1):19-28. PubMed ID: 8674810
    [Abstract] [Full Text] [Related]

  • 13. Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.
    Jimenez-Feltstrom J, Lundquist I, Salehi A.
    Cell Tissue Res; 2005 Feb 30; 319(2):221-30. PubMed ID: 15558323
    [Abstract] [Full Text] [Related]

  • 14. Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.
    Hui H, Yu R, Bousquet C, Perfetti R.
    Endocrinology; 2002 Sep 30; 143(9):3529-39. PubMed ID: 12193567
    [Abstract] [Full Text] [Related]

  • 15. Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic beta-cells.
    Miura Y, Matsui H.
    Am J Physiol Endocrinol Metab; 2003 Nov 30; 285(5):E1001-9. PubMed ID: 14534075
    [Abstract] [Full Text] [Related]

  • 16. Glucagon-like peptide-1 affects gene transcription and messenger ribonucleic acid stability of components of the insulin secretory system in RIN 1046-38 cells.
    Wang Y, Egan JM, Raygada M, Nadiv O, Roth J, Montrose-Rafizadeh C.
    Endocrinology; 1995 Nov 30; 136(11):4910-7. PubMed ID: 7588224
    [Abstract] [Full Text] [Related]

  • 17. Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling.
    Kemp DM, Ubeda M, Habener JF.
    Mol Cell Endocrinol; 2002 Jun 14; 191(2):157-66. PubMed ID: 12062899
    [Abstract] [Full Text] [Related]

  • 18. Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation.
    Chepurny OG, Holz GG.
    Cell Tissue Res; 2002 Feb 14; 307(2):191-201. PubMed ID: 11845326
    [Abstract] [Full Text] [Related]

  • 19. Cooperative enhancement of insulinotropic action of GLP-1 by acetylcholine uncovers paradoxical inhibitory effect of beta cell muscarinic receptor activation on adenylate cyclase activity.
    Miguel JC, Abdel-Wahab YH, Green BD, Mathias PC, Flatt PR.
    Biochem Pharmacol; 2003 Jan 15; 65(2):283-92. PubMed ID: 12504804
    [Abstract] [Full Text] [Related]

  • 20. Interaction of GLP-I and leptin at rat pancreatic B-cells: effects on insulin secretion and signal transduction.
    Fehmann HC, Bode HP, Ebert T, Karl A, Göke B.
    Horm Metab Res; 1997 Nov 15; 29(11):572-6. PubMed ID: 9479558
    [Abstract] [Full Text] [Related]

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