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Journal Abstract Search


188 related items for PubMed ID: 12167656

  • 1. Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2.
    Tsai AL, Palmer G, Wu G, Peng S, Okeley NM, van der Donk WA, Kulmacz RJ.
    J Biol Chem; 2002 Oct 11; 277(41):38311-21. PubMed ID: 12167656
    [Abstract] [Full Text] [Related]

  • 2. Structural characterization of arachidonyl radicals formed by prostaglandin H synthase-2 and prostaglandin H synthase-1 reconstituted with mangano protoporphyrin IX.
    Tsai Al, Palmer G, Xiao G, Swinney DC, Kulmacz RJ.
    J Biol Chem; 1998 Feb 13; 273(7):3888-94. PubMed ID: 9461572
    [Abstract] [Full Text] [Related]

  • 3. Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2.
    Xiao G, Tsai AL, Palmer G, Boyar WC, Marshall PJ, Kulmacz RJ.
    Biochemistry; 1997 Feb 18; 36(7):1836-45. PubMed ID: 9048568
    [Abstract] [Full Text] [Related]

  • 4. Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.
    Tsai AL, Wu G, Rogge CE, Lü JM, Peng S, van der Donk WA, Palmer G, Gerfen GJ, Kulmacz RJ.
    J Inorg Biochem; 2011 Mar 18; 105(3):366-74. PubMed ID: 21421123
    [Abstract] [Full Text] [Related]

  • 5. Identification of Tyr504 as an alternative tyrosyl radical site in human prostaglandin H synthase-2.
    Rogge CE, Liu W, Wu G, Wang LH, Kulmacz RJ, Tsai AL.
    Biochemistry; 2004 Feb 17; 43(6):1560-8. PubMed ID: 14769032
    [Abstract] [Full Text] [Related]

  • 6. Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid.
    Tsai A, Kulmacz RJ, Palmer G.
    J Biol Chem; 1995 May 05; 270(18):10503-8. PubMed ID: 7737984
    [Abstract] [Full Text] [Related]

  • 7. Cyclooxygenase reaction mechanism of PGHS--evidence for a reversible transition between a pentadienyl radical and a new tyrosyl radical by nitric oxide trapping.
    Lü JM, Rogge CE, Wu G, Kulmacz RJ, van der Donk WA, Tsai AL.
    J Inorg Biochem; 2011 Mar 05; 105(3):356-65. PubMed ID: 21403766
    [Abstract] [Full Text] [Related]

  • 8. Rapid kinetics of tyrosyl radical formation and heme redox state changes in prostaglandin H synthase-1 and -2.
    Tsai Al, Wu G, Palmer G, Bambai B, Koehn JA, Marshall PJ, Kulmacz RJ.
    J Biol Chem; 1999 Jul 30; 274(31):21695-700. PubMed ID: 10419480
    [Abstract] [Full Text] [Related]

  • 9. Characterization of the tyrosyl radicals in ovine prostaglandin H synthase-1 by isotope replacement and site-directed mutagenesis.
    Tsai A, Hsi LC, Kulmacz RJ, Palmer G, Smith WL.
    J Biol Chem; 1994 Feb 18; 269(7):5085-91. PubMed ID: 8106487
    [Abstract] [Full Text] [Related]

  • 10. Oxyferryl heme and not tyrosyl radical is the likely culprit in prostaglandin H synthase-1 peroxidase inactivation.
    Wu G, Rogge CE, Wang JS, Kulmacz RJ, Palmer G, Tsai AL.
    Biochemistry; 2007 Jan 16; 46(2):534-42. PubMed ID: 17209563
    [Abstract] [Full Text] [Related]

  • 11. Nitric oxide trapping of tyrosyl radicals generated during prostaglandin endoperoxide synthase turnover. Detection of the radical derivative of tyrosine 385.
    Goodwin DC, Gunther MR, Hsi LC, Crews BC, Eling TE, Mason RP, Marnett LJ.
    J Biol Chem; 1998 Apr 10; 273(15):8903-9. PubMed ID: 9535872
    [Abstract] [Full Text] [Related]

  • 12. Substrate-induced free radicals in prostaglandin H synthase.
    Kulmacz RJ, Palmer G, Tsai AL.
    J Lipid Mediat; 1993 Apr 10; 6(1-3):145-54. PubMed ID: 8395237
    [Abstract] [Full Text] [Related]

  • 13. Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects.
    Wu G, Lü JM, van der Donk WA, Kulmacz RJ, Tsai AL.
    J Inorg Biochem; 2011 Mar 10; 105(3):382-90. PubMed ID: 21394223
    [Abstract] [Full Text] [Related]

  • 14. Prostaglandin H synthase. Kinetics of tyrosyl radical formation and of cyclooxygenase catalysis.
    Tsai AL, Palmer G, Kulmacz RJ.
    J Biol Chem; 1992 Sep 05; 267(25):17753-9. PubMed ID: 1325448
    [Abstract] [Full Text] [Related]

  • 15. Role of Tyr348 in Tyr385 radical dynamics and cyclooxygenase inhibitor interactions in prostaglandin H synthase-2.
    Rogge CE, Ho B, Liu W, Kulmacz RJ, Tsai AL.
    Biochemistry; 2006 Jan 17; 45(2):523-32. PubMed ID: 16401081
    [Abstract] [Full Text] [Related]

  • 16. High-field EPR study of tyrosyl radicals in prostaglandin H(2) synthase-1.
    Dorlet P, Seibold SA, Babcock GT, Gerfen GJ, Smith WL, Tsai AL, Un S.
    Biochemistry; 2002 May 14; 41(19):6107-14. PubMed ID: 11994006
    [Abstract] [Full Text] [Related]

  • 17. Electron paramagnetic resonance and electron nuclear double resonance spectroscopic identification and characterization of the tyrosyl radicals in prostaglandin H synthase 1.
    Shi W, Hoganson CW, Espe M, Bender CJ, Babcock GT, Palmer G, Kulmacz RJ, Tsai Al.
    Biochemistry; 2000 Apr 11; 39(14):4112-21. PubMed ID: 10747802
    [Abstract] [Full Text] [Related]

  • 18. Reaction and free radical kinetics of prostaglandin H synthase with manganese protoporphyrin IX as the prosthetic group.
    Kulmacz RJ, Palmer G, Wei C, Tsai AL.
    Biochemistry; 1994 May 10; 33(18):5428-39. PubMed ID: 8180166
    [Abstract] [Full Text] [Related]

  • 19. Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2.
    Wu G, Tsai AL, Kulmacz RJ.
    Biochemistry; 2009 Dec 22; 48(50):11902-11. PubMed ID: 19894761
    [Abstract] [Full Text] [Related]

  • 20. Peroxide-induced radical formation at TYR385 and TYR504 in human PGHS-1.
    Rogge CE, Liu W, Kulmacz RJ, Tsai AL.
    J Inorg Biochem; 2009 Jun 22; 103(6):912-22. PubMed ID: 19433337
    [Abstract] [Full Text] [Related]


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