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Journal Abstract Search

88 related items for PubMed ID: 12174880

  • 1. Adenoviral transfer of antisenses or ribozyme to O6-methylguanine-DNA methyltransferase mRNA in brain-tumor model resistant to chloroethyl-nitrosourea.
    Manome Y, Yoshinaga H, Watanabe M, Ohno T.
    Anticancer Res; 2002; 22(4):2029-36. PubMed ID: 12174880
    [Abstract] [Full Text] [Related]

  • 2. Development of a syngenic brain-tumor model resistant to chloroethyl-nitrosourea using a methylguanine DNA methyltransferase cDNA.
    Manome Y, Watanabe M, Futaki K, Ishiguro H, Iwagami S, Noda K, Dobashi H, Ochiai Y, Ohara Y, Sanuki K, Kunieda T, Ohno T.
    Anticancer Res; 1999; 19(6B):5313-8. PubMed ID: 10697554
    [Abstract] [Full Text] [Related]

  • 3. Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
    Sato K, Kitajima Y, Nakagawachi T, Soejima H, Miyoshi A, Koga Y, Miyazaki K.
    Oncol Rep; 2005 May; 13(5):899-906. PubMed ID: 15809756
    [Abstract] [Full Text] [Related]

  • 4. Expression of O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea resistance of human brain tumors.
    Nagane M, Asai A, Shibui S, Nomura K, Matsutani M, Kuchino Y.
    Jpn J Clin Oncol; 1992 Jun; 22(3):143-9. PubMed ID: 1518162
    [Abstract] [Full Text] [Related]

  • 5. Elevated expression of DNA polymerase beta gene in glioma cell lines with acquired resistance to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea.
    Gomi A, Shinoda S, Sakai R, Hirai H, Ozawa K, Masuzawa T.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):558-63. PubMed ID: 8878552
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds.
    Tanaka S, Kobayashi I, Utsuki S, Oka H, Yasui Y, Fujii K.
    Oncol Rep; 2005 Nov 14; 14(5):1275-80. PubMed ID: 16211296
    [Abstract] [Full Text] [Related]

  • 7. Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA.
    Zhang Q, Ohannesian DW, Kreklau EL, Erickson LC.
    J Pharmacol Exp Ther; 2001 Jul 14; 298(1):141-7. PubMed ID: 11408535
    [Abstract] [Full Text] [Related]

  • 8. Application of antisense ribonucleic acid complementary to O6-methylguanine-deoxyribonucleic acid methyltransferase messenger ribonucleic acid for therapy of malignant gliomas.
    Nagane M, Asai A, Shibui S, Nomura K, Kuchino Y.
    Neurosurgery; 1997 Aug 14; 41(2):434-40; discussion 440-1. PubMed ID: 9257312
    [Abstract] [Full Text] [Related]

  • 9. In situ detection of O6-methylguanine-DNA methyltransferase messenger RNA in paraffin-embedded human astrocytic tumor tissues by nested in situ RT-PCR is useful in predicting chemotherapy-resistance of tumors.
    Ohe N, Saio M, Kijima M, Tamakawa N, Suwa T, Kojima Y, Yano H, Kaku Y, Iwama T, Shinoda J, Sakai N, Takami T.
    Int J Oncol; 2003 Mar 14; 22(3):543-9. PubMed ID: 12579307
    [Abstract] [Full Text] [Related]

  • 10. Induction of the DNA repair gene O6-methylguanine-DNA methyltransferase by dexamethasone in glioblastomas.
    Ueda S, Mineta T, Nakahara Y, Okamoto H, Shiraishi T, Tabuchi K.
    J Neurosurg; 2004 Oct 14; 101(4):659-63. PubMed ID: 15481722
    [Abstract] [Full Text] [Related]

  • 11. Hammerhead ribozyme-mediated sensitization of human tumor cells after treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Zhang Q, Ohannesian DW, Erickson LC.
    J Pharmacol Exp Ther; 2004 May 14; 309(2):506-14. PubMed ID: 14742745
    [Abstract] [Full Text] [Related]

  • 12. Both extraneuronal monoamine transporter and O(6)-methylguanine-DNA methyltransferase expression influence the antitumor efficacy of 2-chloroethyl-3-sarcosinamide- 1-nitrosourea in human tumor xenografts.
    Chen ZP, Wang ZM, Carter CA, Alley MC, Mohr G, Panasci LC.
    J Pharmacol Exp Ther; 2001 Mar 14; 296(3):712-5. PubMed ID: 11181897
    [Abstract] [Full Text] [Related]

  • 13. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC, Liu JF, Chang JY.
    J Pharmacol Exp Ther; 2006 Feb 14; 316(2):946-54. PubMed ID: 16258022
    [Abstract] [Full Text] [Related]

  • 14. [Study on MGMT assay and tumor individual predictable chemotherapy].
    Zhang YP.
    Ai Zheng; 2004 Jun 14; 23(6):724-34. PubMed ID: 15191682
    [Abstract] [Full Text] [Related]

  • 15. Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients.
    Chen ZP, Yarosh D, Garcia Y, Tampieri D, Mohr G, Malapetsa A, Langleben A, Panasci LC.
    Can J Neurol Sci; 1999 May 14; 26(2):104-9. PubMed ID: 10352868
    [Abstract] [Full Text] [Related]

  • 16. Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase status in glioma: relationship between immunohistochemistry and methylation analysis.
    Sasai K, Nodagashira M, Nishihara H, Aoyanagi E, Wang L, Katoh M, Murata J, Ozaki Y, Ito T, Fujimoto S, Kaneko S, Nagashima K, Tanaka S.
    Am J Surg Pathol; 2008 Aug 14; 32(8):1220-7. PubMed ID: 18580490
    [Abstract] [Full Text] [Related]

  • 17. The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
    Sato K, Kitajima Y, Koga Y, Miyazaki K.
    Anticancer Res; 2005 Aug 14; 25(6B):4021-8. PubMed ID: 16309194
    [Abstract] [Full Text] [Related]

  • 18. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
    Kramer BA, Lemckert FA, Alexander IE, Gunning PW, McCowage GB.
    J Gene Med; 2006 Sep 14; 8(9):1071-85. PubMed ID: 16927363
    [Abstract] [Full Text] [Related]

  • 19. Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.
    Ma LC, Kuo CC, Liu JF, Chen LT, Chang JY.
    Mol Pharmacol; 2008 Aug 14; 74(2):517-26. PubMed ID: 18492797
    [Abstract] [Full Text] [Related]

  • 20. Ribozyme-mediated modulation of human O6-methylguanine-DNA methyltransferase expression.
    Potter PM, Harris LC, Remack JS, Edwards CC, Brent TP.
    Cancer Res; 1993 Apr 15; 53(8):1731-4. PubMed ID: 8467487
    [Abstract] [Full Text] [Related]

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