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Journal Abstract Search

480 related items for PubMed ID: 12177190

  • 1. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
    Wang LJ, Lu YY, Muramatsu S, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Matsushita T, Hanazono Y, Kume A, Nagatsu T, Ozawa K, Nakano I.
    J Neurosci; 2002 Aug 15; 22(16):6920-8. PubMed ID: 12177190
    [Abstract] [Full Text] [Related]

  • 2. Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport.
    Lu YY, Wang LJ, Muramatsu S, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Matsushita T, Hanazono Y, Kume A, Nagatsu T, Ozawa K, Nakano I.
    Neurosci Res; 2003 Jan 15; 45(1):33-40. PubMed ID: 12507722
    [Abstract] [Full Text] [Related]

  • 3. Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.
    Li W, Brakefield D, Pan Y, Hunter D, Myckatyn TM, Parsadanian A.
    Exp Neurol; 2007 Feb 15; 203(2):457-71. PubMed ID: 17034790
    [Abstract] [Full Text] [Related]

  • 4. AAV-NRIP gene therapy ameliorates motor neuron degeneration and muscle atrophy in ALS model mice.
    Chen HH, Yeo HT, Huang YH, Tsai LK, Lai HJ, Tsao YP, Chen SL.
    Skelet Muscle; 2024 Jul 24; 14(1):17. PubMed ID: 39044305
    [Abstract] [Full Text] [Related]

  • 5. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
    Kaspar BK, Lladó J, Sherkat N, Rothstein JD, Gage FH.
    Science; 2003 Aug 08; 301(5634):839-42. PubMed ID: 12907804
    [Abstract] [Full Text] [Related]

  • 6. Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis.
    Mohajeri MH, Figlewicz DA, Bohn MC.
    Hum Gene Ther; 1999 Jul 20; 10(11):1853-66. PubMed ID: 10446925
    [Abstract] [Full Text] [Related]

  • 7. Adeno-associated virus-mediated delivery of glial cell line-derived neurotrophic factor protects motor neuron-like cells from apoptosis.
    Keir SD, Xiao X, Li J, Kennedy PG.
    J Neurovirol; 2001 Oct 20; 7(5):437-46. PubMed ID: 11582516
    [Abstract] [Full Text] [Related]

  • 8. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
    Van Dyke JM, Smit-Oistad IM, Macrander C, Krakora D, Meyer MG, Suzuki M.
    Exp Neurol; 2016 Mar 20; 277():275-282. PubMed ID: 26775178
    [Abstract] [Full Text] [Related]

  • 9. Specific Expression of Glial-Derived Neurotrophic Factor in Muscles as Gene Therapy Strategy for Amyotrophic Lateral Sclerosis.
    Mòdol-Caballero G, García-Lareu B, Herrando-Grabulosa M, Verdés S, López-Vales R, Pagès G, Chillón M, Navarro X, Bosch A.
    Neurotherapeutics; 2021 Apr 20; 18(2):1113-1126. PubMed ID: 33786805
    [Abstract] [Full Text] [Related]

  • 10. GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.
    Suzuki M, McHugh J, Tork C, Shelley B, Klein SM, Aebischer P, Svendsen CN.
    PLoS One; 2007 Aug 01; 2(8):e689. PubMed ID: 17668067
    [Abstract] [Full Text] [Related]

  • 11. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
    Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, Kingsman SM, Carmeliet P, Mazarakis ND.
    Nature; 2004 May 27; 429(6990):413-7. PubMed ID: 15164063
    [Abstract] [Full Text] [Related]

  • 12. Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.
    Björklund A, Kirik D, Rosenblad C, Georgievska B, Lundberg C, Mandel RJ.
    Brain Res; 2000 Dec 15; 886(1-2):82-98. PubMed ID: 11119690
    [Abstract] [Full Text] [Related]

  • 13. Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy.
    Acsadi G, Anguelov RA, Yang H, Toth G, Thomas R, Jani A, Wang Y, Ianakova E, Mohammad S, Lewis RA, Shy ME.
    Hum Gene Ther; 2002 Jun 10; 13(9):1047-59. PubMed ID: 12067438
    [Abstract] [Full Text] [Related]

  • 14. Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice.
    Guillot S, Azzouz M, Déglon N, Zurn A, Aebischer P.
    Neurobiol Dis; 2004 Jun 10; 16(1):139-49. PubMed ID: 15207271
    [Abstract] [Full Text] [Related]

  • 15. In vivo gene electroporation of glial cell line-derived neurotrophic factor (GDNF) into skeletal muscle of SOD1 mutant mice.
    Yamamoto M, Kobayashi Y, Li M, Niwa H, Mitsuma N, Ito Y, Muramatsu T, Sobue G.
    Neurochem Res; 2001 Nov 10; 26(11):1201-7. PubMed ID: 11874201
    [Abstract] [Full Text] [Related]

  • 16. Recombinant adeno-associated virus-mediated global anterograde delivery of glial cell line-derived neurotrophic factor to the spinal cord: comparison of rubrospinal and corticospinal tracts in the rat.
    Foust KD, Flotte TR, Reier PJ, Mandel RJ.
    Hum Gene Ther; 2008 Jan 10; 19(1):71-82. PubMed ID: 18072858
    [Abstract] [Full Text] [Related]

  • 17. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.
    Thomsen GM, Alkaslasi M, Vit JP, Lawless G, Godoy M, Gowing G, Shelest O, Svendsen CN.
    Gene Ther; 2017 Apr 10; 24(4):245-252. PubMed ID: 28276446
    [Abstract] [Full Text] [Related]

  • 18. GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD-1) gene.
    Derby ML, Giuliano R, Figlewicz DA, Bohn MC.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2000 Mar 10; 1(2):113-22. PubMed ID: 11467048
    [Abstract] [Full Text] [Related]

  • 19. Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.
    Hottinger AF, Azzouz M, Déglon N, Aebischer P, Zurn AD.
    J Neurosci; 2000 Aug 01; 20(15):5587-93. PubMed ID: 10908595
    [Abstract] [Full Text] [Related]

  • 20. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis.
    Manabe Y, Nagano I, Gazi MS, Murakami T, Shiote M, Shoji M, Kitagawa H, Setoguchi Y, Abe K.
    Apoptosis; 2002 Aug 01; 7(4):329-34. PubMed ID: 12101392
    [Abstract] [Full Text] [Related]

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