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Journal Abstract Search

151 related items for PubMed ID: 12181422

  • 1. A77 1726 induces differentiation of human myeloid leukemia K562 cells by depletion of intracellular CTP pools.
    Huang M, Wang Y, Collins M, Mitchell BS, Graves LM.
    Mol Pharmacol; 2002 Sep; 62(3):463-72. PubMed ID: 12181422
    [Abstract] [Full Text] [Related]

  • 2. CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase.
    Huang M, Wang Y, Collins M, Graves LM.
    Leukemia; 2004 Nov; 18(11):1857-63. PubMed ID: 15385935
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of the antiproliferative action of leflunomide. A77 1726, the active metabolite of leflunomide, does not block T-cell receptor-mediated signal transduction but its antiproliferative effects are antagonized by pyrimidine nucleosides.
    Cao WW, Kao PN, Chao AC, Gardner P, Ng J, Morris RE.
    J Heart Lung Transplant; 1995 Nov; 14(6 Pt 1):1016-30. PubMed ID: 8719445
    [Abstract] [Full Text] [Related]

  • 4. Cell cycle-dependent regulation of pyrimidine biosynthesis.
    Sigoillot FD, Berkowski JA, Sigoillot SM, Kotsis DH, Guy HI.
    J Biol Chem; 2003 Jan 31; 278(5):3403-9. PubMed ID: 12438317
    [Abstract] [Full Text] [Related]

  • 5. The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function.
    Kirsch BM, Zeyda M, Stuhlmeier K, Grisar J, Smolen JS, Watschinger B, Stulnig TM, Hörl WH, Zlabinger GJ, Säemann MD.
    Arthritis Res Ther; 2005 Jan 31; 7(3):R694-703. PubMed ID: 15899055
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.
    Doscas ME, Williamson AJ, Usha L, Bogachkov Y, Rao GS, Xiao F, Wang Y, Ruby C, Kaufman H, Zhou J, Williams JW, Li Y, Xu X.
    Neoplasia; 2014 Oct 31; 16(10):824-34. PubMed ID: 25379019
    [Abstract] [Full Text] [Related]

  • 7. The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.
    Burger D, Begué-Pastor N, Benavent S, Gruaz L, Kaufmann MT, Chicheportiche R, Dayer JM.
    Rheumatology (Oxford); 2003 Jan 31; 42(1):89-96. PubMed ID: 12509619
    [Abstract] [Full Text] [Related]

  • 8. Identification of the binding site for the allosteric inactivator UTP in mammalian CPS II.
    Zhu LM, Carrey EA.
    Biochem Soc Trans; 1995 Nov 31; 23(4):620S. PubMed ID: 8654805
    [No Abstract] [Full Text] [Related]

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  • 12. Characterization of pyrimidine metabolism in the cellular slime mold, Dictyostelium discoideum.
    Wales ME, Mann-Dean MG, Wild JR.
    Can J Microbiol; 1989 Apr 31; 35(4):432-8. PubMed ID: 2568162
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  • 13. CAD overexpression in mammalian cells.
    Qiu Y, Davidson JN.
    Adv Exp Med Biol; 1998 Apr 31; 431():481-5. PubMed ID: 9598115
    [No Abstract] [Full Text] [Related]

  • 14. Regulation of carbamoyl phosphate synthetase by MAP kinase.
    Graves LM, Guy HI, Kozlowski P, Huang M, Lazarowski E, Pope RM, Collins MA, Dahlstrand EN, Earp HS, Evans DR.
    Nature; 2000 Jan 20; 403(6767):328-32. PubMed ID: 10659854
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  • 15. Effect of polyamines on the carbamoyl-phosphate synthase activity of CAD protein.
    Szondy Z, Matyasi G, Elödi P.
    Acta Biochim Biophys Hung; 1989 Jan 20; 24(1-2):107-17. PubMed ID: 2481915
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  • 17. Uridylate-trapping sugar analogs in combination with inhibitors of uridylate synthesis de novo and 5-fluorouridine.
    Keppler D, Fauler J, Gasser T, Holstege A, Leube K, Schulz-Holstege C, Weckbecker G.
    Adv Enzyme Regul; 1985 Jan 20; 23():61-79. PubMed ID: 2416194
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of HIV replication by A77 1726, the active metabolite of leflunomide, in combination with pyrimidine nucleoside reverse transcriptase inhibitors.
    Hossain MM, Margolis DM.
    J Acquir Immune Defic Syndr; 2001 Oct 01; 28(2):199-201. PubMed ID: 11588518
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  • 20. The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes.
    Palmer G, Burger D, Mezin F, Magne D, Gabay C, Dayer JM, Guerne PA.
    Arthritis Res Ther; 2004 Oct 01; 6(3):R181-9. PubMed ID: 15142263
    [Abstract] [Full Text] [Related]

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