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Journal Abstract Search


610 related items for PubMed ID: 12181739

  • 1. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
    Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM.
    Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
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  • 2. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes.
    Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM.
    EMBO J; 2001 Mar 01; 20(5):998-1009. PubMed ID: 11230124
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  • 3. Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.
    Zou H, Yang R, Hao J, Wang J, Sun C, Fesik SW, Wu JC, Tomaselli KJ, Armstrong RC.
    J Biol Chem; 2003 Mar 07; 278(10):8091-8. PubMed ID: 12506111
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  • 4. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.
    Suzuki Y, Nakabayashi Y, Takahashi R.
    Proc Natl Acad Sci U S A; 2001 Jul 17; 98(15):8662-7. PubMed ID: 11447297
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  • 5. Chemical-induced apoptosis: formation of the Apaf-1 apoptosome.
    Cain K.
    Drug Metab Rev; 2003 Nov 17; 35(4):337-63. PubMed ID: 14705865
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  • 6. Upstream regulatory role for XIAP in receptor-mediated apoptosis.
    Wilkinson JC, Cepero E, Boise LH, Duckett CS.
    Mol Cell Biol; 2004 Aug 17; 24(16):7003-14. PubMed ID: 15282301
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  • 8. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES.
    Nature; 2001 Mar 01; 410(6824):112-6. PubMed ID: 11242052
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  • 9. Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra.
    Ferrer I, Planas AM.
    J Neuropathol Exp Neurol; 2003 Apr 01; 62(4):329-39. PubMed ID: 12722825
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  • 11. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
    Twiddy D, Brown DG, Adrain C, Jukes R, Martin SJ, Cohen GM, MacFarlane M, Cain K.
    J Biol Chem; 2004 May 07; 279(19):19665-82. PubMed ID: 14993223
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  • 14. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.
    Wagenknecht B, Hermisson M, Groscurth P, Liston P, Krammer PH, Weller M.
    J Neurochem; 2000 Dec 07; 75(6):2288-97. PubMed ID: 11080180
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  • 15. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
    Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES.
    J Biol Chem; 2000 Nov 17; 275(46):36152-7. PubMed ID: 10950947
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  • 16. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein.
    Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM.
    J Biol Chem; 2002 Mar 29; 277(13):11345-51. PubMed ID: 11801595
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  • 17. Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells.
    Shawgo ME, Shelton SN, Robertson JD.
    J Biol Chem; 2009 Nov 27; 284(48):33447-55. PubMed ID: 19758996
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  • 18. Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors.
    Wang Z, Cuddy M, Samuel T, Welsh K, Schimmer A, Hanaii F, Houghten R, Pinilla C, Reed JC.
    J Biol Chem; 2004 Nov 12; 279(46):48168-76. PubMed ID: 15337764
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  • 19. PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
    Li T, Zeng L, Gao W, Cui MZ, Fu X, Xu X.
    Biochim Biophys Acta; 2013 Mar 12; 1832(3):453-74. PubMed ID: 23207240
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