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99 related items for PubMed ID: 12181747

  • 1. MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.
    Shonai T, Adachi M, Sakata K, Takekawa M, Endo T, Imai K, Hareyama M.
    Cell Death Differ; 2002 Sep; 9(9):963-71. PubMed ID: 12181747
    [Abstract] [Full Text] [Related]

  • 2. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 3. Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis.
    Belka C, Rudner J, Wesselborg S, Stepczynska A, Marini P, Lepple-Wienhues A, Faltin H, Bamberg M, Budach W, Schulze-Osthoff K.
    Oncogene; 2000 Feb 24; 19(9):1181-90. PubMed ID: 10713706
    [Abstract] [Full Text] [Related]

  • 4. Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
    Miranda MB, McGuire TF, Johnson DE.
    Leukemia; 2002 Apr 24; 16(4):683-92. PubMed ID: 11960350
    [Abstract] [Full Text] [Related]

  • 5. Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibition.
    Scoltock AB, Cidlowski JA.
    Exp Cell Res; 2004 Jul 01; 297(1):212-23. PubMed ID: 15194437
    [Abstract] [Full Text] [Related]

  • 6. Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Gajate C, An F, Mollinedo F.
    Clin Cancer Res; 2003 Apr 01; 9(4):1535-45. PubMed ID: 12684430
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.
    Allan LA, Morrice N, Brady S, Magee G, Pathak S, Clarke PR.
    Nat Cell Biol; 2003 Jul 01; 5(7):647-54. PubMed ID: 12792650
    [Abstract] [Full Text] [Related]

  • 8. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
    Yu C, Rahmani M, Dent P, Grant S.
    Exp Cell Res; 2004 May 01; 295(2):555-66. PubMed ID: 15093752
    [Abstract] [Full Text] [Related]

  • 9. The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways.
    Belka C, Gruber C, Jendrossek V, Wesselborg S, Budach W.
    Oncogene; 2003 Jan 16; 22(2):176-85. PubMed ID: 12527887
    [Abstract] [Full Text] [Related]

  • 10. Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells.
    Falluel-Morel A, Aubert N, Vaudry D, Basille M, Fontaine M, Fournier A, Vaudry H, Gonzalez BJ.
    J Neurochem; 2004 Dec 16; 91(5):1231-43. PubMed ID: 15569266
    [Abstract] [Full Text] [Related]

  • 11. Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death.
    Kim BS, Yoon KH, Oh HM, Choi EY, Kim SW, Han WC, Kim EA, Choi SC, Kim TH, Yun KJ, Kim EC, Lyou JH, Nah YH, Chung HT, Cha YN, Jun CD.
    Cell Immunol; 2002 Dec 16; 220(2):96-106. PubMed ID: 12657244
    [Abstract] [Full Text] [Related]

  • 12. Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner.
    Takagi Y, Du J, Ma XY, Nakashima I, Nagase F.
    Mol Pharmacol; 2004 Mar 16; 65(3):778-87. PubMed ID: 14978257
    [Abstract] [Full Text] [Related]

  • 13. MEK1 and Erk1/2 kinases as targets for the modulation of radiation responses.
    Belka C, Knippers P, Rudner J, Faltin H, Bamberg M, Budach W.
    Anticancer Res; 2000 Mar 16; 20(5A):3243-9. PubMed ID: 11062749
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
    Wen-Sheng W.
    Cancer Lett; 2006 Jul 28; 239(1):27-35. PubMed ID: 16169661
    [Abstract] [Full Text] [Related]

  • 15. Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes.
    Uriarte SM, Joshi-Barve S, Song Z, Sahoo R, Gobejishvili L, Jala VR, Haribabu B, McClain C, Barve S.
    Cell Death Differ; 2005 Mar 28; 12(3):233-42. PubMed ID: 15665818
    [Abstract] [Full Text] [Related]

  • 16. Biomarker assays for phosphorylated MAP kinase. Their utility for measurement of MEK inhibition.
    Sebolt-Leopold JS, Van Becelaere K, Hook K, Herrera R.
    Methods Mol Med; 2003 Mar 28; 85():31-8. PubMed ID: 12710194
    [No Abstract] [Full Text] [Related]

  • 17. Tumor-induced apoptosis of T cells: amplification by a mitochondrial cascade.
    Gastman BR, Yin XM, Johnson DE, Wieckowski E, Wang GQ, Watkins SC, Rabinowich H.
    Cancer Res; 2000 Dec 15; 60(24):6811-7. PubMed ID: 11156370
    [Abstract] [Full Text] [Related]

  • 18. FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway.
    Liu JF, Crépin M, Liu JM, Barritault D, Ledoux D.
    Biochem Biophys Res Commun; 2002 May 17; 293(4):1174-82. PubMed ID: 12054499
    [Abstract] [Full Text] [Related]

  • 19. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH, Schmitz I, Söderström TS, Poukkula M, Johnson VL, Chow SC, Krammer PH, Eriksson JE.
    EMBO J; 2000 Oct 16; 19(20):5418-28. PubMed ID: 11032809
    [Abstract] [Full Text] [Related]

  • 20. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.
    Perkins CL, Fang G, Kim CN, Bhalla KN.
    Cancer Res; 2000 Mar 15; 60(6):1645-53. PubMed ID: 10749135
    [Abstract] [Full Text] [Related]

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