These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

174 related items for PubMed ID: 12183426

  • 1. Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis.
    Machover D, Zittoun J, Saffroy R, Broët P, Giraudier S, Magnaldo T, Goldschmidt E, Debuire B, Orrico M, Tan Y, Mishal Z, Chevallier O, Tonetti C, Jouault H, Ulusakarya A, Tanguy ML, Metzger G, Hoffman RM.
    Cancer Res; 2002 Aug 15; 62(16):4685-9. PubMed ID: 12183426
    [Abstract] [Full Text] [Related]

  • 2. Recombinant Methioninase as a DNA Demethylation Agent.
    Hoffman RM, Machover D.
    Methods Mol Biol; 2019 Aug 15; 1866():279-284. PubMed ID: 30725424
    [Abstract] [Full Text] [Related]

  • 3. Cytotoxic synergism of methioninase in combination with 5-fluorouracil and folinic acid.
    Machover D, Zittoun J, Broët P, Metzger G, Orrico M, Goldschmidt E, Schilf A, Tonetti C, Tan Y, Delmas-Marsalet B, Luccioni C, Falissard B, Hoffman RM.
    Biochem Pharmacol; 2001 Apr 01; 61(7):867-76. PubMed ID: 11274973
    [Abstract] [Full Text] [Related]

  • 4. Methioninase gene therapy of human cancer cells is synergistic with recombinant methioninase treatment.
    Miki K, Al-Refaie W, Xu M, Jiang P, Tan Y, Bouvet M, Zhao M, Gupta A, Chishima T, Shimada H, Makuuchi M, Moossa AR, Hoffman RM.
    Cancer Res; 2000 May 15; 60(10):2696-702. PubMed ID: 10825143
    [Abstract] [Full Text] [Related]

  • 5. Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice.
    Tan Y, Sun X, Xu M, Tan X, Sasson A, Rashidi B, Han Q, Tan X, Wang X, An Z, Sun FX, Hoffman RM.
    Clin Cancer Res; 1999 Aug 15; 5(8):2157-63. PubMed ID: 10473100
    [Abstract] [Full Text] [Related]

  • 6. Survival efficacy of the combination of the methioninase gene and methioninase in a lung cancer orthotopic model.
    Miki K, Xu M, An Z, Wang X, Yang M, Al-Refaie W, Sun X, Baranov E, Tan Y, Chishima T, Shimada H, Moossa AR, Hoffman RM.
    Cancer Gene Ther; 2000 Feb 15; 7(2):332-8. PubMed ID: 10770644
    [Abstract] [Full Text] [Related]

  • 7. PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.
    Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM.
    Cancer Res; 2004 Sep 15; 64(18):6673-8. PubMed ID: 15374983
    [Abstract] [Full Text] [Related]

  • 8. Anticancer efficacy in vivo and in vitro, synergy with 5-fluorouracil, and safety of recombinant methioninase.
    Yoshioka T, Wada T, Uchida N, Maki H, Yoshida H, Ide N, Kasai H, Hojo K, Shono K, Maekawa R, Yagi S, Hoffman RM, Sugita K.
    Cancer Res; 1998 Jun 15; 58(12):2583-7. PubMed ID: 9635582
    [Abstract] [Full Text] [Related]

  • 9. Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy.
    Tan Y, Xu M, Tan X, Tan X, Wang X, Saikawa Y, Nagahama T, Sun X, Lenz M, Hoffman RM.
    Protein Expr Purif; 1997 Mar 15; 9(2):233-45. PubMed ID: 9056489
    [Abstract] [Full Text] [Related]

  • 10. Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients.
    Tan Y, Zavala J, Han Q, Xu M, Sun X, Tan X, Tan X, Magana R, Geller J, Hoffman RM.
    Anticancer Res; 1997 Mar 15; 17(5B):3857-60. PubMed ID: 9427792
    [Abstract] [Full Text] [Related]

  • 11. Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.
    Tan Y, Sun X, Xu M, An Z, Tan X, Han Q, Miljkovic DA, Yang M, Hoffman RM.
    Protein Expr Purif; 1998 Feb 15; 12(1):45-52. PubMed ID: 9473456
    [Abstract] [Full Text] [Related]

  • 12. Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.
    Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM.
    Cancer Res; 2004 Aug 15; 64(16):5775-8. PubMed ID: 15313919
    [Abstract] [Full Text] [Related]

  • 13. In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.
    Sun X, Yang Z, Li S, Tan Y, Zhang N, Wang X, Yagi S, Yoshioka T, Takimoto A, Mitsushima K, Suginaka A, Frenkel EP, Hoffman RM.
    Cancer Res; 2003 Dec 01; 63(23):8377-83. PubMed ID: 14678999
    [Abstract] [Full Text] [Related]

  • 14. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
    Ren Q, Van Groeningen CJ, Hardcastle A, Aherne GW, Geoffroy F, Allegra CJ, Johnston PG, Grem JL.
    Oncol Res; 1997 Dec 01; 9(2):77-88. PubMed ID: 9167189
    [Abstract] [Full Text] [Related]

  • 15. Enhanced cytotoxicity with interleukin-1 alpha and 5-fluorouracil in HCT116 colon cancer cells.
    Geoffroy FJ, Allegra CJ, Sinha B, Grem JL.
    Oncol Res; 1994 Dec 01; 6(12):581-91. PubMed ID: 7787251
    [Abstract] [Full Text] [Related]

  • 16.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 17. Broad selective efficacy of recombinant methioninase and polyethylene glycol-modified recombinant methioninase on cancer cells In Vitro.
    Tan Y, Xu M, Hoffman RM.
    Anticancer Res; 2010 Apr 01; 30(4):1041-6. PubMed ID: 20530407
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. Alterations of constitutive pericentromeric heterochromatin in lymphocytes of cancer patients and lymphocytes exposed to 5-azacytidine is associated with DNA-hypomethylation.
    Shvachko LP.
    Exp Oncol; 2008 Sep 01; 30(3):230-4. PubMed ID: 18806747
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 9.