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314 related items for PubMed ID: 12183458

  • 1. Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.
    Perrot V, Vazquez-Prado J, Gutkind JS.
    J Biol Chem; 2002 Nov 08; 277(45):43115-20. PubMed ID: 12183458
    [Abstract] [Full Text] [Related]

  • 2. The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.
    Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL.
    Proc Natl Acad Sci U S A; 2002 Sep 17; 99(19):12085-90. PubMed ID: 12196628
    [Abstract] [Full Text] [Related]

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  • 4. Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B.
    Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS.
    Cancer Res; 2004 Aug 01; 64(15):5212-24. PubMed ID: 15289326
    [Abstract] [Full Text] [Related]

  • 5. Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.
    Swiercz JM, Kuner R, Behrens J, Offermanns S.
    Neuron; 2002 Jul 03; 35(1):51-63. PubMed ID: 12123608
    [Abstract] [Full Text] [Related]

  • 6. Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.
    Hirotani M, Ohoka Y, Yamamoto T, Nirasawa H, Furuyama T, Kogo M, Matsuya T, Inagaki S.
    Biochem Biophys Res Commun; 2002 Sep 13; 297(1):32-7. PubMed ID: 12220504
    [Abstract] [Full Text] [Related]

  • 7. B plexins activate Rho through PDZ-RhoGEF.
    Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG.
    FEBS Lett; 2002 Oct 09; 529(2-3):168-72. PubMed ID: 12372594
    [Abstract] [Full Text] [Related]

  • 8. Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential.
    Chikumi H, Barac A, Behbahani B, Gao Y, Teramoto H, Zheng Y, Gutkind JS.
    Oncogene; 2004 Jan 08; 23(1):233-40. PubMed ID: 14712228
    [Abstract] [Full Text] [Related]

  • 9. Characterization of the expression of PDZ-RhoGEF, LARG and G(alpha)12/G(alpha)13 proteins in the murine nervous system.
    Kuner R, Swiercz JM, Zywietz A, Tappe A, Offermanns S.
    Eur J Neurosci; 2002 Dec 08; 16(12):2333-41. PubMed ID: 12492428
    [Abstract] [Full Text] [Related]

  • 10. Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho.
    Fukuhara S, Chikumi H, Gutkind JS.
    FEBS Lett; 2000 Nov 24; 485(2-3):183-8. PubMed ID: 11094164
    [Abstract] [Full Text] [Related]

  • 11. Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.
    Swiercz JM, Worzfeld T, Offermanns S.
    Mol Cell Biol; 2009 Dec 24; 29(23):6321-34. PubMed ID: 19805522
    [Abstract] [Full Text] [Related]

  • 12. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase.
    Chikumi H, Fukuhara S, Gutkind JS.
    J Biol Chem; 2002 Apr 05; 277(14):12463-73. PubMed ID: 11799111
    [Abstract] [Full Text] [Related]

  • 13. Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).
    Jaiswal M, Gremer L, Dvorsky R, Haeusler LC, Cirstea IC, Uhlenbrock K, Ahmadian MR.
    J Biol Chem; 2011 May 20; 286(20):18202-12. PubMed ID: 21454492
    [Abstract] [Full Text] [Related]

  • 14. Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2.
    Swiercz JM, Kuner R, Offermanns S.
    J Cell Biol; 2004 Jun 21; 165(6):869-80. PubMed ID: 15210733
    [Abstract] [Full Text] [Related]

  • 15. Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
    Pascoe HG, Gutowski S, Chen H, Brautigam CA, Chen Z, Sternweis PC, Zhang X.
    Proc Natl Acad Sci U S A; 2015 Dec 01; 112(48):14852-7. PubMed ID: 26627240
    [Abstract] [Full Text] [Related]

  • 16. Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho.
    Driessens MH, Hu H, Nobes CD, Self A, Jordens I, Goodman CS, Hall A.
    Curr Biol; 2001 Mar 06; 11(5):339-44. PubMed ID: 11267870
    [Abstract] [Full Text] [Related]

  • 17. Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton.
    Banerjee J, Wedegaertner PB.
    Mol Biol Cell; 2004 Apr 06; 15(4):1760-75. PubMed ID: 14742719
    [Abstract] [Full Text] [Related]

  • 18. PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.
    Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS.
    J Biol Chem; 2013 Apr 26; 288(17):12232-43. PubMed ID: 23467409
    [Abstract] [Full Text] [Related]

  • 19. Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.
    Booden MA, Siderovski DP, Der CJ.
    Mol Cell Biol; 2002 Jun 26; 22(12):4053-61. PubMed ID: 12024019
    [Abstract] [Full Text] [Related]

  • 20. Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF.
    Taya S, Inagaki N, Sengiku H, Makino H, Iwamatsu A, Urakawa I, Nagao K, Kataoka S, Kaibuchi K.
    J Cell Biol; 2001 Nov 26; 155(5):809-20. PubMed ID: 11724822
    [Abstract] [Full Text] [Related]

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