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281 related items for PubMed ID: 12194220

  • 1. Promotion of photodynamic therapy-induced apoptosis by the mitochondrial protein Smac/DIABLO: dependence on Bax.
    Usuda J, Chiu SM, Azizuddin K, Xue LY, Lam M, Nieminen AL, Oleinick NL.
    Photochem Photobiol; 2002 Aug; 76(2):217-23. PubMed ID: 12194220
    [Abstract] [Full Text] [Related]

  • 2. Real-time single cell analysis of Smac/DIABLO release during apoptosis.
    Rehm M, Düssmann H, Prehn JH.
    J Cell Biol; 2003 Sep 15; 162(6):1031-43. PubMed ID: 12975347
    [Abstract] [Full Text] [Related]

  • 3. Kinetics of Smac/DIABLO release from mitochondria during apoptosis of MCF-7 breast cancer cells.
    Gorka M, Godlewski MM, Gajkowska B, Wojewodzka U, Motyl T.
    Cell Biol Int; 2004 Sep 15; 28(11):741-54. PubMed ID: 15563396
    [Abstract] [Full Text] [Related]

  • 4. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP, Bonavida B.
    Mol Cancer Ther; 2002 Oct 15; 1(12):1051-8. PubMed ID: 12481428
    [Abstract] [Full Text] [Related]

  • 5. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A, Gillissen B, Müller A, Normand G, Hemmati PG, Schuler M, Dörken B, Daniel PT.
    Oncogene; 2004 Jun 03; 23(26):4523-35. PubMed ID: 15064710
    [Abstract] [Full Text] [Related]

  • 6. Impaired kinetics of Bax-GFP and Smac/DIABLO-GFP in caspase-8- and bid-silenced and Bcl-2 overexpressed breast cancer MCF-7 cells exposed to camptothecin.
    Górka M, Lamparska-Przybysz M, Motyl T.
    Cell Mol Biol (Noisy-le-grand); 2007 Jan 21; 52 Suppl():OL915-22. PubMed ID: 17666167
    [Abstract] [Full Text] [Related]

  • 7. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H, Bhalla K, Wang HG.
    Cancer Res; 2003 Apr 01; 63(7):1483-9. PubMed ID: 12670894
    [Abstract] [Full Text] [Related]

  • 8. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
    Adrain C, Creagh EM, Martin SJ.
    EMBO J; 2001 Dec 03; 20(23):6627-36. PubMed ID: 11726499
    [Abstract] [Full Text] [Related]

  • 10. Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization.
    Madesh M, Antonsson B, Srinivasula SM, Alnemri ES, Hajnóczky G.
    J Biol Chem; 2002 Feb 15; 277(7):5651-9. PubMed ID: 11741882
    [Abstract] [Full Text] [Related]

  • 11. Association between the photodynamic loss of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy.
    Usuda J, Azizuddin K, Chiu SM, Oleinick NL.
    Photochem Photobiol; 2003 Jul 15; 78(1):1-8. PubMed ID: 12929741
    [Abstract] [Full Text] [Related]

  • 12. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
    Deng Y, Lin Y, Wu X.
    Genes Dev; 2002 Jan 01; 16(1):33-45. PubMed ID: 11782443
    [Abstract] [Full Text] [Related]

  • 13. Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event.
    Xue LY, Chiu SM, Oleinick NL.
    Exp Cell Res; 2001 Feb 01; 263(1):145-55. PubMed ID: 11161713
    [Abstract] [Full Text] [Related]

  • 14. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
    Zhang XD, Borrow JM, Zhang XY, Nguyen T, Hersey P.
    Oncogene; 2003 May 15; 22(19):2869-81. PubMed ID: 12771938
    [Abstract] [Full Text] [Related]

  • 15. Bisphenol A diglycidyl ether-induced apoptosis involves Bax/Bid-dependent mitochondrial release of apoptosis-inducing factor (AIF), cytochrome c and Smac/DIABLO.
    Fehlberg S, Gregel CM, Göke A, Göke R.
    Br J Pharmacol; 2003 Jun 15; 139(3):495-500. PubMed ID: 12788809
    [Abstract] [Full Text] [Related]

  • 16. Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy.
    Chiu SM, Xue LY, Usuda J, Azizuddin K, Oleinick NL.
    Br J Cancer; 2003 Oct 20; 89(8):1590-7. PubMed ID: 14562036
    [Abstract] [Full Text] [Related]

  • 17. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
    Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES.
    J Biol Chem; 2000 Nov 17; 275(46):36152-7. PubMed ID: 10950947
    [Abstract] [Full Text] [Related]

  • 18. Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats.
    Hu XL, Olsson T, Johansson IM, Brännström T, Wester P.
    Eur J Neurosci; 2004 Sep 17; 20(5):1177-88. PubMed ID: 15341589
    [Abstract] [Full Text] [Related]

  • 19. Pterostilbene induces mitochondrially derived apoptosis in breast cancer cells in vitro.
    Moon D, McCormack D, McDonald D, McFadden D.
    J Surg Res; 2013 Apr 17; 180(2):208-15. PubMed ID: 22572619
    [Abstract] [Full Text] [Related]

  • 20. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis.
    Guo F, Nimmanapalli R, Paranawithana S, Wittman S, Griffin D, Bali P, O'Bryan E, Fumero C, Wang HG, Bhalla K.
    Blood; 2002 May 01; 99(9):3419-26. PubMed ID: 11964312
    [Abstract] [Full Text] [Related]

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