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256 related items for PubMed ID: 12203009

  • 1. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium.
    Marini V, Kasparkova J, Novakova O, Monsú Scolaro L, Romeo R, Brabec V.
    J Biol Inorg Chem; 2002 Sep; 7(7-8):725-34. PubMed ID: 12203009
    [Abstract] [Full Text] [Related]

  • 2. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking.
    Kaspárková J, Nováková O, Vrána O, Farrell N, Brabec V.
    Biochemistry; 1999 Aug 24; 38(34):10997-1005. PubMed ID: 10460154
    [Abstract] [Full Text] [Related]

  • 3. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
    Kasparkova J, Vrana O, Farrell N, Brabec V.
    J Inorg Biochem; 2004 Oct 24; 98(10):1560-9. PubMed ID: 15458817
    [Abstract] [Full Text] [Related]

  • 4. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J, Novakova O, Farrell N, Brabec V.
    Biochemistry; 2003 Jan 28; 42(3):792-800. PubMed ID: 12534292
    [Abstract] [Full Text] [Related]

  • 5. Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents.
    Kloster M, Kostrhunova H, Zaludova R, Malina J, Kasparkova J, Brabec V, Farrell N.
    Biochemistry; 2004 Jun 22; 43(24):7776-86. PubMed ID: 15196020
    [Abstract] [Full Text] [Related]

  • 6. Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl(2)(Me(2)SO(4))(4)Ru] in cell-free media.
    Nováková O, Hofr C, Brabec V.
    Biochem Pharmacol; 2000 Dec 15; 60(12):1761-71. PubMed ID: 11108791
    [Abstract] [Full Text] [Related]

  • 7. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ, Davies MS, Cox JW, Thomas DS, Farrell N.
    Chemistry; 2003 Feb 03; 9(3):713-25. PubMed ID: 12569464
    [Abstract] [Full Text] [Related]

  • 8. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
    Kasparkova J, Marini V, Najajreh Y, Gibson D, Brabec V.
    Biochemistry; 2003 May 27; 42(20):6321-32. PubMed ID: 12755637
    [Abstract] [Full Text] [Related]

  • 9. DNA cross-linking patterns induced by an antitumor-active trinuclear platinum complex and comparison with its dinuclear analogue.
    Zhu J, Zhao Y, Zhu Y, Wu Z, Lin M, He W, Wang Y, Chen G, Dong L, Zhang J, Lu Y, Guo Z.
    Chemistry; 2009 May 27; 15(21):5245-53. PubMed ID: 19350599
    [Abstract] [Full Text] [Related]

  • 10. DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media.
    Novakova O, Chen H, Vrana O, Rodger A, Sadler PJ, Brabec V.
    Biochemistry; 2003 Oct 07; 42(39):11544-54. PubMed ID: 14516206
    [Abstract] [Full Text] [Related]

  • 11. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].
    Brabec V, Christofis P, Slámová M, Kostrhunová H, Nováková O, Najajreh Y, Gibson D, Kaspárková J.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1887-900. PubMed ID: 17400194
    [Abstract] [Full Text] [Related]

  • 12. DNA interactions of bifunctional dinuclear platinum(II) antitumor agents.
    Zaludová R, Zákovská A, Kasparková J, Balcarová Z, Kleinwächter V, Vrána O, Farrell N, Brabec V.
    Eur J Biochem; 1997 Jun 01; 246(2):508-17. PubMed ID: 9208945
    [Abstract] [Full Text] [Related]

  • 13. Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(III) in cell-free media.
    Malina J, Novakova O, Keppler BK, Alessio E, Brabec V.
    J Biol Inorg Chem; 2001 Apr 01; 6(4):435-45. PubMed ID: 11372202
    [Abstract] [Full Text] [Related]

  • 14. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)2(N7-acyclovir)]+.
    Balcarová Z, Kaspárková J, Zákovská A, Nováková O, Sivo MF, Natile G, Brabec V.
    Mol Pharmacol; 1998 May 01; 53(5):846-55. PubMed ID: 9584210
    [Abstract] [Full Text] [Related]

  • 15. Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.
    Stehlíková K, Kaspárková J, Nováková O, Martínez A, Moreno V, Brabec V.
    FEBS J; 2006 Jan 01; 273(2):301-14. PubMed ID: 16403018
    [Abstract] [Full Text] [Related]

  • 16. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V, Kaspárková J, Vrána O, Nováková O, Cox JW, Qu Y, Farrell N.
    Biochemistry; 1999 May 25; 38(21):6781-90. PubMed ID: 10346899
    [Abstract] [Full Text] [Related]

  • 17. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J, Vojtiskova M, Natile G, Brabec V.
    Chemistry; 2008 May 25; 14(4):1330-41. PubMed ID: 18022972
    [Abstract] [Full Text] [Related]

  • 18. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies.
    Kaspárková J, Mellish KJ, Qu Y, Brabec V, Farrell N.
    Biochemistry; 1996 Dec 24; 35(51):16705-13. PubMed ID: 8988007
    [Abstract] [Full Text] [Related]

  • 19. DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.
    Malina J, Hofr C, Maresca L, Natile G, Brabec V.
    Biophys J; 2000 Apr 24; 78(4):2008-21. PubMed ID: 10733979
    [Abstract] [Full Text] [Related]

  • 20. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N.
    J Am Chem Soc; 2004 Feb 25; 126(7):2166-80. PubMed ID: 14971952
    [Abstract] [Full Text] [Related]

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