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220 related items for PubMed ID: 12206774

  • 1. Mutational analysis of the uracil DNA glycosylase inhibitor protein and its interaction with Escherichia coli uracil DNA glycosylase.
    Acharya N, Roy S, Varshney U.
    J Mol Biol; 2002 Aug 23; 321(4):579-90. PubMed ID: 12206774
    [Abstract] [Full Text] [Related]

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  • 3. Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase.
    Putnam CD, Shroyer MJ, Lundquist AJ, Mol CD, Arvai AS, Mosbaugh DW, Tainer JA.
    J Mol Biol; 1999 Mar 26; 287(2):331-46. PubMed ID: 10080896
    [Abstract] [Full Text] [Related]

  • 4. The role of leucine 191 of Escherichia coli uracil DNA glycosylase in the formation of a highly stable complex with the substrate mimic, ugi, and in uracil excision from the synthetic substrates.
    Handa P, Roy S, Varshney U.
    J Biol Chem; 2001 May 18; 276(20):17324-31. PubMed ID: 11278852
    [Abstract] [Full Text] [Related]

  • 5. Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition.
    Acharya N, Talawar RK, Saikrishnan K, Vijayan M, Varshney U.
    Nucleic Acids Res; 2003 Dec 15; 31(24):7216-26. PubMed ID: 14654697
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.
    Mol CD, Arvai AS, Sanderson RJ, Slupphaug G, Kavli B, Krokan HE, Mosbaugh DW, Tainer JA.
    Cell; 1995 Sep 08; 82(5):701-8. PubMed ID: 7671300
    [Abstract] [Full Text] [Related]

  • 7. Site-directed mutagenesis and characterization of uracil-DNA glycosylase inhibitor protein. Role of specific carboxylic amino acids in complex formation with Escherichia coli uracil-DNA glycosylase.
    Lundquist AJ, Beger RD, Bennett SE, Bolton PH, Mosbaugh DW.
    J Biol Chem; 1997 Aug 22; 272(34):21408-19. PubMed ID: 9261156
    [Abstract] [Full Text] [Related]

  • 8. Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme and substrate.
    Handa P, Acharya N, Varshney U.
    Nucleic Acids Res; 2002 Jul 15; 30(14):3086-95. PubMed ID: 12136091
    [Abstract] [Full Text] [Related]

  • 9. Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
    Xiao G, Tordova M, Jagadeesh J, Drohat AC, Stivers JT, Gilliland GL.
    Proteins; 1999 Apr 01; 35(1):13-24. PubMed ID: 10090282
    [Abstract] [Full Text] [Related]

  • 10. X-ray analysis of a complex of Escherichia coli uracil DNA glycosylase (EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG.
    Ravishankar R, Bidya Sagar M, Roy S, Purnapatre K, Handa P, Varshney U, Vijayan M.
    Nucleic Acids Res; 1998 Nov 01; 26(21):4880-7. PubMed ID: 9776748
    [Abstract] [Full Text] [Related]

  • 11. Use of a coupled transcriptional system for consistent overexpression and purification of UDG-Ugi complex and Ugi from Escherichia coli.
    Roy S, Purnapatre K, Handa P, Boyanapalli M, Varshney U.
    Protein Expr Purif; 1998 Jul 01; 13(2):155-62. PubMed ID: 9675057
    [Abstract] [Full Text] [Related]

  • 12. Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity.
    Chembazhi UV, Patil VV, Sah S, Reeve W, Tiwari RP, Woo E, Varshney U.
    Nucleic Acids Res; 2017 Jun 02; 45(10):5863-5876. PubMed ID: 28369586
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the Escherichia coli uracil-DNA glycosylase.inhibitor protein complex.
    Bennett SE, Mosbaugh DW.
    J Biol Chem; 1992 Nov 05; 267(31):22512-21. PubMed ID: 1429601
    [Abstract] [Full Text] [Related]

  • 14. Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis.
    Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA.
    Cell; 1995 Mar 24; 80(6):869-78. PubMed ID: 7697717
    [Abstract] [Full Text] [Related]

  • 15. Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase.
    Stivers JT, Pankiewicz KW, Watanabe KA.
    Biochemistry; 1999 Jan 19; 38(3):952-63. PubMed ID: 9893991
    [Abstract] [Full Text] [Related]

  • 16. Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG.
    Saikrishnan K, Bidya Sagar M, Ravishankar R, Roy S, Purnapatre K, Handa P, Varshney U, Vijayan M.
    Acta Crystallogr D Biol Crystallogr; 2002 Aug 19; 58(Pt 8):1269-76. PubMed ID: 12136137
    [Abstract] [Full Text] [Related]

  • 17. Increased spontaneous mutation frequency in human cells expressing the phage PBS2-encoded inhibitor of uracil-DNA glycosylase.
    Radany EH, Dornfeld KJ, Sanderson RJ, Savage MK, Majumdar A, Seidman MM, Mosbaugh DW.
    Mutat Res; 2000 Sep 15; 461(1):41-58. PubMed ID: 10980411
    [Abstract] [Full Text] [Related]

  • 18. Identification of specific carboxyl groups on uracil-DNA glycosylase inhibitor protein that are required for activity.
    Sanderson RJ, Mosbaugh DW.
    J Biol Chem; 1996 Nov 15; 271(46):29170-81. PubMed ID: 8910574
    [Abstract] [Full Text] [Related]

  • 19. Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase.
    Cole AR, Ofer S, Ryzhenkova K, Baltulionis G, Hornyak P, Savva R.
    Nucleic Acids Res; 2013 Oct 15; 41(18):8760-75. PubMed ID: 23892286
    [Abstract] [Full Text] [Related]

  • 20. Cloning and expression of the uracil-DNA glycosylase inhibitor (UGI) from bacteriophage PBS-1 and crystallization of a uracil-DNA glycosylase-UGI complex.
    Savva R, Pearl LH.
    Proteins; 1995 Jul 15; 22(3):287-9. PubMed ID: 7479702
    [Abstract] [Full Text] [Related]

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