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132 related items for PubMed ID: 12206817

  • 1. Pretreatment of rats with the inducing agents phenobarbitone and 3-methylcholanthrene ameliorates the toxicity of chromium (VI) in hepatocytes.
    Gunaratnam M, Pohlscheidt M, Grant MH.
    Toxicol In Vitro; 2002 Oct; 16(5):509-16. PubMed ID: 12206817
    [Abstract] [Full Text] [Related]

  • 2. The role of glutathione reductase in the cytotoxicity of chromium (VI) in isolated rat hepatocytes.
    Gunaratnam M, Grant MH.
    Chem Biol Interact; 2001 Apr 16; 134(2):191-202. PubMed ID: 11311213
    [Abstract] [Full Text] [Related]

  • 3. Biological reactive intermediates that mediate chromium (VI) toxicity.
    Pourahmad J, O'Brien PJ.
    Adv Exp Med Biol; 2001 Apr 16; 500():203-7. PubMed ID: 11764936
    [Abstract] [Full Text] [Related]

  • 4. The role of reduced glutathione and glutathione reductase in the cytotoxicity of chromium (VI) in osteoblasts.
    Ning J, Grant MH.
    Toxicol In Vitro; 2000 Aug 16; 14(4):329-35. PubMed ID: 10906439
    [Abstract] [Full Text] [Related]

  • 5. Cr (VI) inhibits DNA, RNA and protein syntheses in hepatocytes: involvement of glutathione reductase, reduced glutathione and DT-diaphorase.
    Gunaratnam M, Grant MH.
    Toxicol In Vitro; 2008 Jun 16; 22(4):879-86. PubMed ID: 18321676
    [Abstract] [Full Text] [Related]

  • 6. The activity of xenobiotic enzymes and the cytotoxicity of mitoxantrone in MCF 7 human breast cancer cells treated with inducing agents.
    Li SJ, Rodgers EH, Grant MH.
    Chem Biol Interact; 1995 Jul 14; 97(2):101-18. PubMed ID: 7541730
    [Abstract] [Full Text] [Related]

  • 7. Phenobarbital-induced cytosolic cytoprotective mechanisms that offset increases in NADPH cytochrome P450 reductase activity in menadione-mediated cytotoxicity.
    Utley WS, Mehendale HM.
    Toxicol Appl Pharmacol; 1989 Jun 15; 99(2):323-33. PubMed ID: 2544042
    [Abstract] [Full Text] [Related]

  • 8. Prominent role of DT-diaphorase as a cellular mechanism reducing chromium(VI) and reverting its mutagenicity.
    De Flora S, Morelli A, Basso C, Romano M, Serra D, De Flora A.
    Cancer Res; 1985 Jul 15; 45(7):3188-96. PubMed ID: 4005852
    [Abstract] [Full Text] [Related]

  • 9. Microsomal metabolism of hexavalent chromium. Inhibitory effect of oxygen and involvement of cytochrome P-450.
    Mikalsen A, Alexander J, Ryberg D.
    Chem Biol Interact; 1989 Jul 15; 69(2-3):175-92. PubMed ID: 2495190
    [Abstract] [Full Text] [Related]

  • 10. Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved?
    Aiyar J, De Flora S, Wetterhahn KE.
    Carcinogenesis; 1992 Jul 15; 13(7):1159-66. PubMed ID: 1379126
    [Abstract] [Full Text] [Related]

  • 11. The interaction of chromium (VI) with macrophages: depletion of glutathione and inhibition of glutathione reductase.
    Lalaouni A, Henderson C, Kupper C, Grant MH.
    Toxicology; 2007 Jul 01; 236(1-2):76-81. PubMed ID: 17498860
    [Abstract] [Full Text] [Related]

  • 12. Effect of phenobarbital and 3-methylcholanthrene on the early oxidative stress component induced by lindane in rat liver.
    Junqueira VB, Simizu K, Pimentel R, Azzalis LA, Barros SB, Koch O, Videla LA.
    Xenobiotica; 1991 Aug 01; 21(8):1053-65. PubMed ID: 1723229
    [Abstract] [Full Text] [Related]

  • 13. Effects of phenobarbital and 3-methylcholanthrene pretreatment on size, sedimentation velocity, and mixed function oxygenase activity of rat hepatocytes.
    Sweeney GD, Jones KG, Krestynski F.
    J Lab Clin Med; 1978 Mar 01; 91(3):444-54. PubMed ID: 415100
    [Abstract] [Full Text] [Related]

  • 14. Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.
    Lash LH, Putt DA, Huang P, Hueni SE, Parker JC.
    Toxicology; 2007 Jun 03; 235(1-2):11-26. PubMed ID: 17433522
    [Abstract] [Full Text] [Related]

  • 15. Polychlorinated biphenyl isomers and congeners as inducers of both 3-methylcholanthrene- and phenobarbitone-type microsomal enzyme activity.
    Parkinson A, Cockerline R, Safe S.
    Chem Biol Interact; 1980 Mar 03; 29(3):277-89. PubMed ID: 6766814
    [Abstract] [Full Text] [Related]

  • 16. In vivo nephrotoxicity induced in mice by chromium(VI). Involvement of glutathione and chromium(V).
    Hojo Y, Satomi Y.
    Biol Trace Elem Res; 1991 Oct 03; 31(1):21-31. PubMed ID: 1724173
    [Abstract] [Full Text] [Related]

  • 17. [Protective effect of reduced glutathione on cytotoxicity induced by hexavalent chromium [Cr(VI)] in L-02 hepatocyte].
    Wang HH, Xiao JW, Li B, Zhong CG.
    Wei Sheng Yan Jiu; 2006 Jul 03; 35(4):414-5. PubMed ID: 16986511
    [Abstract] [Full Text] [Related]

  • 18. Reductive metabolism and protein binding of chromium(VI) by P450 protein enzymes.
    Mikalsen A, Alexander J, Wallin H, Ingelman-Sundberg M, Andersen RA.
    Carcinogenesis; 1991 May 03; 12(5):825-31. PubMed ID: 1903091
    [Abstract] [Full Text] [Related]

  • 19. Phenobarbital-induced cytoprotective mechanisms in menadione metabolism: the role of glutathione reductase and DT-diaphorase.
    Utley WS, Mehendale HM.
    Int J Biochem; 1990 May 03; 22(9):957-67. PubMed ID: 1704318
    [Abstract] [Full Text] [Related]

  • 20. Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.
    Ringel M, von Mach MA, Santos R, Feilen PJ, Brulport M, Hermes M, Bauer AW, Schormann W, Tanner B, Schön MR, Oesch F, Hengstler JG.
    Toxicology; 2005 Jan 05; 206(1):153-67. PubMed ID: 15590115
    [Abstract] [Full Text] [Related]

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