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260 related items for PubMed ID: 12208474

  • 1. Transgenic overexpression of human lecithin: cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition.
    Furbee JW, Parks JS.
    Atherosclerosis; 2002 Nov; 165(1):89-100. PubMed ID: 12208474
    [Abstract] [Full Text] [Related]

  • 2. Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
    Furbee JW, Sawyer JK, Parks JS.
    J Biol Chem; 2002 Feb 01; 277(5):3511-9. PubMed ID: 11719520
    [Abstract] [Full Text] [Related]

  • 3. Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice.
    Föger B, Chase M, Amar MJ, Vaisman BL, Shamburek RD, Paigen B, Fruchart-Najib J, Paiz JA, Koch CA, Hoyt RF, Brewer HB, Santamarina-Fojo S.
    J Biol Chem; 1999 Dec 24; 274(52):36912-20. PubMed ID: 10601244
    [Abstract] [Full Text] [Related]

  • 4. Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.
    Lee RG, Kelley KL, Sawyer JK, Farese RV, Parks JS, Rudel LL.
    Circ Res; 2004 Nov 12; 95(10):998-1004. PubMed ID: 15486318
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of human lecithin:cholesterol acyltransferase in mice offers no protection against diet-induced atherosclerosis.
    Mehlum A, Gjernes E, Solberg LA, Hagve TA, Prydz H.
    APMIS; 2000 May 12; 108(5):336-42. PubMed ID: 10937770
    [Abstract] [Full Text] [Related]

  • 6. Mice overexpressing human lecithin: cholesterol acyltransferase are not protected against diet-induced atherosclerosis.
    Mehlum A, Muri M, Hagve TA, Solberg LA, Prydz H.
    APMIS; 1997 Nov 12; 105(11):861-8. PubMed ID: 9393557
    [Abstract] [Full Text] [Related]

  • 7. In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
    Furbee JW, Francone O, Parks JS.
    J Lipid Res; 2002 Mar 12; 43(3):428-37. PubMed ID: 11893779
    [Abstract] [Full Text] [Related]

  • 8. Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis.
    Hoeg JM, Santamarina-Fojo S, Bérard AM, Cornhill JF, Herderick EE, Feldman SH, Haudenschild CC, Vaisman BL, Hoyt RF, Demosky SJ, Kauffman RD, Hazel CM, Marcovina SM, Brewer HB.
    Proc Natl Acad Sci U S A; 1996 Oct 15; 93(21):11448-53. PubMed ID: 8876155
    [Abstract] [Full Text] [Related]

  • 9. Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits.
    Hoeg JM, Vaisman BL, Demosky SJ, Meyn SM, Talley GD, Hoyt RF, Feldman S, Bérard AM, Sakai N, Wood D, Brousseau ME, Marcovina S, Brewer HB, Santamarina-Fojo S.
    J Biol Chem; 1996 Feb 23; 271(8):4396-402. PubMed ID: 8626790
    [Abstract] [Full Text] [Related]

  • 10. Alteration of plasma HDL cholesteryl ester composition with transgenic expression of a point mutation (E149A) of human LCAT.
    Furbee JW, Francone O, Parks JS.
    J Lipid Res; 2001 Oct 23; 42(10):1626-35. PubMed ID: 11590219
    [Abstract] [Full Text] [Related]

  • 11. Tissue-specific expression of the human gene for lecithin: cholesterol acyltransferase in transgenic mice alters blood lipids, lipoproteins and lipases towards a less atherogenic profile.
    Mehlum A, Staels B, Duverger N, Tailleux A, Castro G, Fievet C, Luc G, Fruchart JC, Olivecrona G, Skretting G.
    Eur J Biochem; 1995 Jun 01; 230(2):567-75. PubMed ID: 7607230
    [Abstract] [Full Text] [Related]

  • 12. Lecithin/cholesterol acyltransferase modulates diet-induced hepatic deposition of triglycerides in mice.
    Karavia EA, Papachristou DJ, Kotsikogianni I, Triantafyllidou IE, Kypreos KE.
    J Nutr Biochem; 2013 Mar 01; 24(3):567-77. PubMed ID: 22819565
    [Abstract] [Full Text] [Related]

  • 13. Dietary fatty acid modification of HDL phospholipid molecular species alters lecithin: cholesterol acyltransferase reactivity in cynomolgus monkeys.
    Thornburg JT, Parks JS, Rudel LL.
    J Lipid Res; 1995 Feb 01; 36(2):277-89. PubMed ID: 7751815
    [Abstract] [Full Text] [Related]

  • 14. Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.
    Lambert G, Sakai N, Vaisman BL, Neufeld EB, Marteyn B, Chan CC, Paigen B, Lupia E, Thomas A, Striker LJ, Blanchette-Mackie J, Csako G, Brady JN, Costello R, Striker GE, Remaley AT, Brewer HB, Santamarina-Fojo S.
    J Biol Chem; 2001 May 04; 276(18):15090-8. PubMed ID: 11278414
    [Abstract] [Full Text] [Related]

  • 15. Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins.
    Zhao Y, Thorngate FE, Weisgraber KH, Williams DL, Parks JS.
    Biochemistry; 2005 Jan 25; 44(3):1013-25. PubMed ID: 15654758
    [Abstract] [Full Text] [Related]

  • 16. Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice.
    Thacker SG, Rousset X, Esmail S, Zarzour A, Jin X, Collins HL, Sampson M, Stonik J, Demosky S, Malide DA, Freeman L, Vaisman BL, Kruth HS, Adelman SJ, Remaley AT.
    J Lipid Res; 2015 Jul 25; 56(7):1282-95. PubMed ID: 25964513
    [Abstract] [Full Text] [Related]

  • 17. High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase.
    Bérard AM, Föger B, Remaley A, Shamburek R, Vaisman BL, Talley G, Paigen B, Hoyt RF, Marcovina S, Brewer HB, Santamarina-Fojo S.
    Nat Med; 1997 Jul 25; 3(7):744-9. PubMed ID: 9212100
    [Abstract] [Full Text] [Related]

  • 18. Expression of human lecithin-cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein AI and human apolipoprotein all on plasma lipoprotein cholesterol metabolism.
    Francone OL, Gong EL, Ng DS, Fielding CJ, Rubin EM.
    J Clin Invest; 1995 Sep 25; 96(3):1440-8. PubMed ID: 7657816
    [Abstract] [Full Text] [Related]

  • 19. Atherosclerosis in aged mice over-expressing the reverse cholesterol transport genes.
    Berti JA, de Faria EC, Oliveira HC.
    Braz J Med Biol Res; 2005 Mar 25; 38(3):391-8. PubMed ID: 15761619
    [Abstract] [Full Text] [Related]

  • 20. ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.
    Joyce CW, Wagner EM, Basso F, Amar MJ, Freeman LA, Shamburek RD, Knapper CL, Syed J, Wu J, Vaisman BL, Fruchart-Najib J, Billings EM, Paigen B, Remaley AT, Santamarina-Fojo S, Brewer HB.
    J Biol Chem; 2006 Nov 03; 281(44):33053-65. PubMed ID: 16928680
    [Abstract] [Full Text] [Related]

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