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436 related items for PubMed ID: 12208748

  • 1. Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer.
    Freytag SO, Khil M, Stricker H, Peabody J, Menon M, DePeralta-Venturina M, Nafziger D, Pegg J, Paielli D, Brown S, Barton K, Lu M, Aguilar-Cordova E, Kim JH.
    Cancer Res; 2002 Sep 01; 62(17):4968-76. PubMed ID: 12208748
    [Abstract] [Full Text] [Related]

  • 2. Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer.
    Freytag SO, Stricker H, Pegg J, Paielli D, Pradhan DG, Peabody J, DePeralta-Venturina M, Xia X, Brown S, Lu M, Kim JH.
    Cancer Res; 2003 Nov 01; 63(21):7497-506. PubMed ID: 14612551
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of the biodistribution, persistence, toxicity, and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse.
    Paielli DL, Wing MS, Rogulski KR, Gilbert JD, Kolozsvary A, Kim JH, Hughes J, Schnell M, Thompson T, Freytag SO.
    Mol Ther; 2000 Mar 01; 1(3):263-74. PubMed ID: 10933942
    [Abstract] [Full Text] [Related]

  • 4. Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy.
    Xie Y, Gilbert JD, Kim JH, Freytag SO.
    Clin Cancer Res; 1999 Dec 01; 5(12):4224-32. PubMed ID: 10632364
    [Abstract] [Full Text] [Related]

  • 5. Gene transfer into human prostate adenocarcinoma cells with an adenoviral vector: Hyperthermia enhances a double suicide gene expression, cytotoxicity and radiotoxicity.
    Lee YJ, Lee H, Borrelli MJ.
    Cancer Gene Ther; 2002 Mar 01; 9(3):267-74. PubMed ID: 11896443
    [Abstract] [Full Text] [Related]

  • 6. Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line.
    Trinh QT, Austin EA, Murray DM, Knick VC, Huber BE.
    Cancer Res; 1995 Nov 01; 55(21):4808-12. PubMed ID: 7585511
    [Abstract] [Full Text] [Related]

  • 7. A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy.
    DeWeese TL, van der Poel H, Li S, Mikhak B, Drew R, Goemann M, Hamper U, DeJong R, Detorie N, Rodriguez R, Haulk T, DeMarzo AM, Piantadosi S, Yu DC, Chen Y, Henderson DR, Carducci MA, Nelson WG, Simons JW.
    Cancer Res; 2001 Oct 15; 61(20):7464-72. PubMed ID: 11606381
    [Abstract] [Full Text] [Related]

  • 8. Cytosine deaminase versus thymidine kinase: a comparison of the antitumor activity.
    Corban-Wilhelm H, Becker G, Bauder-Wüst U, Greulich D, Debus J.
    Clin Exp Med; 2003 Nov 15; 3(3):150-6. PubMed ID: 14648229
    [Abstract] [Full Text] [Related]

  • 9. Replicating adenoviral vector-mediated transfer of a heat-inducible double suicide gene for gene therapy.
    Lee YJ, Galoforo SS, Battle P, Lee H, Corry PM, Jessup JM.
    Cancer Gene Ther; 2001 Jun 15; 8(6):397-404. PubMed ID: 11498759
    [Abstract] [Full Text] [Related]

  • 10. Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization.
    Rogulski KR, Wing MS, Paielli DL, Gilbert JD, Kim JH, Freytag SO.
    Hum Gene Ther; 2000 Jan 01; 11(1):67-76. PubMed ID: 10646640
    [Abstract] [Full Text] [Related]

  • 11. Selective radiosensitization of 9L glioma in the brain transduced with double suicide fusion gene.
    Kim JH, Kolozsvary A, Rogulski K, Khil MS, Brown SL, Freytag SO.
    Cancer J Sci Am; 1998 Jan 01; 4(6):364-9. PubMed ID: 9853135
    [Abstract] [Full Text] [Related]

  • 12. Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity.
    Barton KN, Paielli D, Zhang Y, Koul S, Brown SL, Lu M, Seely J, Kim JH, Freytag SO.
    Mol Ther; 2006 Feb 01; 13(2):347-56. PubMed ID: 16290236
    [Abstract] [Full Text] [Related]

  • 13. Adenoviral-mediated transfer of a heat-inducible double suicide gene into prostate carcinoma cells.
    Blackburn RV, Galoforo SS, Corry PM, Lee YJ.
    Cancer Res; 1998 Apr 01; 58(7):1358-62. PubMed ID: 9537229
    [Abstract] [Full Text] [Related]

  • 14. Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data.
    Teh BS, Ayala G, Aguilar L, Mai WY, Timme TL, Vlachaki MT, Miles B, Kadmon D, Wheeler T, Caillouet J, Davis M, Carpenter LS, Lu HH, Chiu JK, Woo SY, Thompson T, Aguilar-Cordova E, Butler EB.
    Int J Radiat Oncol Biol Phys; 2004 Apr 01; 58(5):1520-9. PubMed ID: 15050332
    [Abstract] [Full Text] [Related]

  • 15. A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.
    Small EJ, Carducci MA, Burke JM, Rodriguez R, Fong L, van Ummersen L, Yu DC, Aimi J, Ando D, Working P, Kirn D, Wilding G.
    Mol Ther; 2006 Jul 01; 14(1):107-17. PubMed ID: 16690359
    [Abstract] [Full Text] [Related]

  • 16. Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cancer.
    van der Linden RR, Haagmans BL, Mongiat-Artus P, van Doornum GJ, Kraaij R, Kadmon D, Aguilar-Cordova E, Osterhaus AD, van der Kwast TH, Bangma CH.
    Eur Urol; 2005 Jul 01; 48(1):153-61. PubMed ID: 15967266
    [Abstract] [Full Text] [Related]

  • 17. Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes.
    Hajri A, Wack S, Lehn P, Vigneron JP, Lehn JM, Marescaux J, Aprahamian M.
    Cancer Gene Ther; 2004 Jan 01; 11(1):16-27. PubMed ID: 14681723
    [Abstract] [Full Text] [Related]

  • 18. Adenovirus mediated cytosine deaminase gene transduction and 5-fluorocytosine therapy sensitizes mouse prostate cancer cells to irradiation.
    Anello R, Cohen S, Atkinson G, Hall SJ.
    J Urol; 2000 Dec 01; 164(6):2173-7. PubMed ID: 11061950
    [Abstract] [Full Text] [Related]

  • 19. Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model.
    Moriuchi S, Wolfe D, Tamura M, Yoshimine T, Miura F, Cohen JB, Glorioso JC.
    Gene Ther; 2002 May 01; 9(9):584-91. PubMed ID: 11973634
    [Abstract] [Full Text] [Related]

  • 20. Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model.
    Freytag SO, Paielli D, Wing M, Rogulski K, Brown S, Kolozsvary A, Seely J, Barton K, Dragovic A, Kim JH.
    Int J Radiat Oncol Biol Phys; 2002 Nov 01; 54(3):873-85. PubMed ID: 12377341
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