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Journal Abstract Search


446 related items for PubMed ID: 12213056

  • 1. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L, Pérez-Silanes S, Oficialdegui AM, Martínez-Esparza J, Del Castillo JC, Mourelle M, Langer T, Guccione S, Donzella G, Krovat EM, Poptodorov K, Lasheras B, Ballaz S, Hervías I, Tordera R, Del Río J, Monge A.
    J Med Chem; 2002 Sep 12; 45(19):4128-39. PubMed ID: 12213056
    [Abstract] [Full Text] [Related]

  • 2. New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.
    Martínez-Esparza J, Oficialdegui AM, Pérez-Silanes S, Heras B, Orús L, Palop JA, Lasheras B, Roca J, Mourelle M, Bosch A, Del Castillo JC, Tordera R, Del Río J, Monge A.
    J Med Chem; 2001 Feb 01; 44(3):418-28. PubMed ID: 11462981
    [Abstract] [Full Text] [Related]

  • 3. Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain.
    Duncan MJ, Hensler JG.
    Neuropharmacology; 2002 Jul 01; 43(1):36-44. PubMed ID: 12213257
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of 5-HT(1A) receptors in hippocampal and cortical homogenates.
    Alper RH, Nelson DL.
    Eur J Pharmacol; 2000 Feb 25; 390(1-2):67-73. PubMed ID: 10708708
    [Abstract] [Full Text] [Related]

  • 5. 5-Hydroxytryptamine(1A) receptor-stimulated [(35)S]GTPgammaS binding in rat brain: absence of regional differences in coupling efficiency.
    Meller E, Li H, Carr KD, Hiller JM.
    J Pharmacol Exp Ther; 2000 Feb 25; 292(2):684-91. PubMed ID: 10640306
    [Abstract] [Full Text] [Related]

  • 6. Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.
    Li Q, Wichems C, Heils A, Van De Kar LD, Lesch KP, Murphy DL.
    J Pharmacol Exp Ther; 1999 Dec 25; 291(3):999-1007. PubMed ID: 10565817
    [Abstract] [Full Text] [Related]

  • 7. Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.
    Hughes ZA, Starr KR, Langmead CJ, Hill M, Bartoszyk GD, Hagan JJ, Middlemiss DN, Dawson LA.
    Eur J Pharmacol; 2005 Mar 07; 510(1-2):49-57. PubMed ID: 15740724
    [Abstract] [Full Text] [Related]

  • 8. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Martínez J, Pérez S, Oficialdegui AM, Heras B, Orús L, Villanueva H, Palop JA, Roca J, Mourelle M, Bosch A, Del Castillo JC, Lasheras B, Tordera R, del Río J, Monge A.
    Eur J Med Chem; 2001 Jan 07; 36(1):55-61. PubMed ID: 11231049
    [Abstract] [Full Text] [Related]

  • 9. S 14506: novel receptor coupling at 5-HT(1A) receptors.
    Milligan G, Kellett E, Dacquet C, Dubreuil V, Jacoby E, Millan MJ, Lavielle G, Spedding M.
    Neuropharmacology; 2001 Mar 07; 40(3):334-44. PubMed ID: 11166326
    [Abstract] [Full Text] [Related]

  • 10. Active conformation of some arylpiperazine postsynaptic 5-HT(1A) receptor antagonists.
    Paluchowska MH, Bojarski AJ, Charakchieva-Minol S, Wesołowska A.
    Eur J Med Chem; 2002 Apr 07; 37(4):273-83. PubMed ID: 11960662
    [Abstract] [Full Text] [Related]

  • 11. 5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.
    Matzen L, van Amsterdam C, Rautenberg W, Greiner HE, Harting J, Seyfried CA, Böttcher H.
    J Med Chem; 2000 Mar 23; 43(6):1149-57. PubMed ID: 10737747
    [Abstract] [Full Text] [Related]

  • 12. Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist.
    Page ME, Cryan JF, Sullivan A, Dalvi A, Saucy B, Manning DR, Lucki I.
    J Pharmacol Exp Ther; 2002 Sep 23; 302(3):1220-7. PubMed ID: 12183683
    [Abstract] [Full Text] [Related]

  • 13. Differential modulation by GTPgammaS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [3H]-WAY100,635.
    Newman-Tancredi A, Verrièle L, Millan MJ.
    Br J Pharmacol; 2001 Jan 23; 132(2):518-24. PubMed ID: 11159702
    [Abstract] [Full Text] [Related]

  • 14. SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.
    Watson J, Roberts C, Scott C, Kendall I, Collin L, Day NC, Harries MH, Soffin E, Davies CH, Randall AD, Heightman T, Gaster L, Wyman P, Parker C, Price GW, Middlemiss DN.
    Br J Pharmacol; 2001 Jul 23; 133(6):797-806. PubMed ID: 11454652
    [Abstract] [Full Text] [Related]

  • 15. The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.
    Rasmussen K, Calligaro DO, Czachura JF, Dreshfield-Ahmad LJ, Evans DC, Hemrick-Luecke SK, Kallman MJ, Kendrick WT, Leander JD, Nelson DL, Overshiner CD, Wainscott DB, Wolff MC, Wong DT, Branchek TA, Zgombick JM, Xu YC.
    J Pharmacol Exp Ther; 2000 Aug 23; 294(2):688-700. PubMed ID: 10900249
    [Abstract] [Full Text] [Related]

  • 16. Antidepressant-like activity of VN2222, a serotonin reuptake inhibitor with high affinity at 5-HT1A receptors.
    Tordera RM, Monge A, Del Río J, Lasheras B.
    Eur J Pharmacol; 2002 May 03; 442(1-2):63-71. PubMed ID: 12020683
    [Abstract] [Full Text] [Related]

  • 17. Correlation between low/high affinity ratios for 5-HT(1A) receptors and intrinsic activity.
    Assié MB, Cosi C, Koek W.
    Eur J Pharmacol; 1999 Dec 10; 386(1):97-103. PubMed ID: 10611469
    [Abstract] [Full Text] [Related]

  • 18. Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Newman-Tancredi A, Verrièle L, Chaput C, Millan MJ.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 10; 357(3):205-17. PubMed ID: 9550290
    [Abstract] [Full Text] [Related]

  • 19. 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.
    Hedlund PB, Kelly L, Mazur C, Lovenberg T, Sutcliffe JG, Bonaventure P.
    Eur J Pharmacol; 2004 Mar 08; 487(1-3):125-32. PubMed ID: 15033384
    [Abstract] [Full Text] [Related]

  • 20. Characterization of 5-HT1A receptor-mediated [35S]GTPgammaS binding in rat hippocampal membranes.
    Alper RH, Nelson DL.
    Eur J Pharmacol; 1998 Feb 19; 343(2-3):303-12. PubMed ID: 9570480
    [Abstract] [Full Text] [Related]


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