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Journal Abstract Search

151 related items for PubMed ID: 12213059

  • 1. 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.
    Nielsen FE, Bodvarsdottir TB, Worsaae A, MacKay P, Stidsen CE, Boonen HC, Pridal L, Arkhammar PO, Wahl P, Ynddal L, Junager F, Dragsted N, Tagmose TM, Mogensen JP, Koch A, Treppendahl SP, Hansen JB.
    J Med Chem; 2002 Sep 12; 45(19):4171-87. PubMed ID: 12213059
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  • 2. New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells.
    Nielsen FE, Ebdrup S, Jensen AF, Ynddal L, Bodvarsdottir TB, Stidsen C, Worsaae A, Boonen HC, Arkhammar PO, Fremming T, Wahl P, Kornø HT, Hansen JB.
    J Med Chem; 2006 Jul 13; 49(14):4127-39. PubMed ID: 16821773
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  • 3. 3-Alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: design, synthesis, and pharmacological evaluation.
    Pirotte B, Ouedraogo R, de Tullio P, Khelili S, Somers F, Boverie S, Dupont L, Fontaine J, Damas J, Lebrun P.
    J Med Chem; 2000 Apr 20; 43(8):1456-66. PubMed ID: 10780901
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  • 4. Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues.
    Dabrowski M, Larsen T, Ashcroft FM, Bondo Hansen J, Wahl P.
    Diabetologia; 2003 Oct 20; 46(10):1375-82. PubMed ID: 12961066
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  • 5. The actions of a novel potent islet beta-cell specific ATP-sensitive K+ channel opener can be modulated by syntaxin-1A acting on sulfonylurea receptor 1.
    Ng B, Kang Y, Elias CL, He Y, Xie H, Hansen JB, Wahl P, Gaisano HY.
    Diabetes; 2007 Aug 20; 56(8):2124-34. PubMed ID: 17496234
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  • 6. Hydroxylated analogues of ATP-sensitive potassium channel openers belonging to the group of 6- and/or 7-substituted 3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides: toward an improvement in sulfonylurea receptor 1 selectivity and metabolism stability.
    de Tullio P, Servais AC, Fillet M, Gillotin F, Somers F, Chiap P, Lebrun P, Pirotte B.
    J Med Chem; 2011 Dec 22; 54(24):8353-61. PubMed ID: 22077416
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  • 10. Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.
    Tagmose TM, Schou SC, Mogensen JP, Nielsen FE, Arkhammar PO, Wahl P, Hansen BS, Worsaae A, Boonen HC, Antoine MH, Lebrun P, Hansen JB.
    J Med Chem; 2004 Jun 03; 47(12):3202-11. PubMed ID: 15163199
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  • 14. 2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?
    Ouedraogo R, Becker B, Boverie S, Somers F, Antoine MH, Pirotte B, Lebrun P, de Tullio P.
    Biol Chem; 2002 Nov 03; 383(11):1759-68. PubMed ID: 12530541
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  • 15. Towards selective Kir6.2/SUR1 potassium channel openers, medicinal chemistry and therapeutic perspectives.
    Hansen JB.
    Curr Med Chem; 2006 Nov 03; 13(4):361-76. PubMed ID: 16475928
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  • 16. Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity.
    Somers F, Ouedraogo R, Antoine MH, de Tullio P, Becker B, Fontaine J, Damas J, Dupont L, Rigo B, Delarge J, Lebrun P, Pirotte B.
    J Med Chem; 2001 Aug 02; 44(16):2575-85. PubMed ID: 11472211
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  • 18. Preparation and pharmacological evaluation of the R- and S-enantiomers of 3-(2-butylamino)-4H- and 3-(3-methyl-2-butylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide, two tissue selective ATP-sensitive potassium channel openers.
    Khelili S, de Tullio P, Lebrun P, Fillet M, Antoine MH, Ouedraogo R, Dupont L, Fontaine J, Felekidis A, Leclerc G, Delarge J, Pirotte B.
    Bioorg Med Chem; 1999 Aug 02; 7(8):1513-20. PubMed ID: 10482443
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  • 19. Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.
    Cosgrove KE, Straub SG, Barnes PD, Chapman J, Sharp GW, Dunne MJ.
    Eur J Pharmacol; 2004 Feb 20; 486(2):133-9. PubMed ID: 14975702
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