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1763 related items for PubMed ID: 12218097

  • 1. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 2. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH, Schmitz I, Söderström TS, Poukkula M, Johnson VL, Chow SC, Krammer PH, Eriksson JE.
    EMBO J; 2000 Oct 16; 19(20):5418-28. PubMed ID: 11032809
    [Abstract] [Full Text] [Related]

  • 3. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
    Thomas WD, Zhang XD, Franco AV, Nguyen T, Hersey P.
    J Immunol; 2000 Nov 15; 165(10):5612-20. PubMed ID: 11067917
    [Abstract] [Full Text] [Related]

  • 4. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.
    Suliman A, Lam A, Datta R, Srivastava RK.
    Oncogene; 2001 Apr 19; 20(17):2122-33. PubMed ID: 11360196
    [Abstract] [Full Text] [Related]

  • 5. Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.
    Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M.
    J Biol Chem; 2003 Nov 07; 278(45):44338-47. PubMed ID: 12920112
    [Abstract] [Full Text] [Related]

  • 6. Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by inhibiting cytochrome c release.
    Gibson EM, Henson ES, Haney N, Villanueva J, Gibson SB.
    Cancer Res; 2002 Jan 15; 62(2):488-96. PubMed ID: 11809700
    [Abstract] [Full Text] [Related]

  • 7. Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death.
    Aouad SM, Cohen LY, Sharif-Askari E, Haddad EK, Alam A, Sekaly RP.
    J Immunol; 2004 Feb 15; 172(4):2316-23. PubMed ID: 14764700
    [Abstract] [Full Text] [Related]

  • 8. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep 15; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 9. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
    Kim YS, Schwabe RF, Qian T, Lemasters JJ, Brenner DA.
    Hepatology; 2002 Dec 15; 36(6):1498-508. PubMed ID: 12447876
    [Abstract] [Full Text] [Related]

  • 10. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M, Cohen GM, Dickens M.
    Biochem J; 2000 May 15; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [Abstract] [Full Text] [Related]

  • 11. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
    [Abstract] [Full Text] [Related]

  • 12. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.
    Harper N, Hughes M, MacFarlane M, Cohen GM.
    J Biol Chem; 2003 Jul 11; 278(28):25534-41. PubMed ID: 12721308
    [Abstract] [Full Text] [Related]

  • 13. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
    Izeradjene K, Douglas L, Delaney AB, Houghton JA.
    Cancer Res; 2004 Nov 01; 64(21):8036-44. PubMed ID: 15520213
    [Abstract] [Full Text] [Related]

  • 14. Stimulation of the mitogen-activated protein kinase pathway antagonizes TRAIL-induced apoptosis downstream of BID cleavage in human breast cancer MCF-7 cells.
    Sarker M, Ruiz-Ruiz C, Robledo G, López-Rivas A.
    Oncogene; 2002 Jun 20; 21(27):4323-7. PubMed ID: 12082620
    [Abstract] [Full Text] [Related]

  • 15. Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
    Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H.
    J Biol Chem; 2001 Aug 31; 276(35):32585-90. PubMed ID: 11384965
    [Abstract] [Full Text] [Related]

  • 16. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
    Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A.
    Immunity; 2000 Jun 31; 12(6):611-20. PubMed ID: 10894161
    [Abstract] [Full Text] [Related]

  • 17. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
    Chou AH, Tsai HF, Wu YY, Hu CY, Hwang LH, Hsu PI, Hsu PN.
    J Immunol; 2005 Feb 15; 174(4):2160-6. PubMed ID: 15699147
    [Abstract] [Full Text] [Related]

  • 18. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW, Guseva NV, Tagiyev AF, Glover RA, Cohen MB.
    Prostate; 2002 Jun 01; 52(1):1-11. PubMed ID: 11992615
    [Abstract] [Full Text] [Related]

  • 19. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
    Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE.
    J Biol Chem; 2001 May 11; 276(19):16484-90. PubMed ID: 11278665
    [Abstract] [Full Text] [Related]

  • 20. Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression.
    Yeh JH, Hsu SC, Han SH, Lai MZ.
    J Exp Med; 1998 Nov 16; 188(10):1795-802. PubMed ID: 9815257
    [Abstract] [Full Text] [Related]

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