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124 related items for PubMed ID: 12225753

  • 1. Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity.
    Finerty PJ, Muhandiram R, Forman-Kay JD.
    J Mol Biol; 2002 Sep 20; 322(3):605-20. PubMed ID: 12225753
    [Abstract] [Full Text] [Related]

  • 2. Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A.
    Li SC, Gish G, Yang D, Coffey AJ, Forman-Kay JD, Ernberg I, Kay LE, Pawson T.
    Curr Biol; 1999 Dec 02; 9(23):1355-62. PubMed ID: 10607564
    [Abstract] [Full Text] [Related]

  • 3. NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain.
    Finerty PJ, Mittermaier AK, Muhandiram R, Kay LE, Forman-Kay JD.
    Biochemistry; 2005 Jan 18; 44(2):694-703. PubMed ID: 15641795
    [Abstract] [Full Text] [Related]

  • 4. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.
    Poy F, Yaffe MB, Sayos J, Saxena K, Morra M, Sumegi J, Cantley LC, Terhorst C, Eck MJ.
    Mol Cell; 1999 Oct 18; 4(4):555-61. PubMed ID: 10549287
    [Abstract] [Full Text] [Related]

  • 5. Backbone dynamics of the C-terminal SH2 domain of the p85alpha subunit of phosphoinositide 3-kinase: effect of phosphotyrosine-peptide binding and characterization of slow conformational exchange processes.
    Kristensen SM, Siegal G, Sankar A, Driscoll PC.
    J Mol Biol; 2000 Jun 09; 299(3):771-88. PubMed ID: 10835283
    [Abstract] [Full Text] [Related]

  • 6. SAP couples Fyn to SLAM immune receptors.
    Chan B, Lanyi A, Song HK, Griesbach J, Simarro-Grande M, Poy F, Howie D, Sumegi J, Terhorst C, Eck MJ.
    Nat Cell Biol; 2003 Feb 09; 5(2):155-60. PubMed ID: 12545174
    [Abstract] [Full Text] [Related]

  • 7. Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation.
    Howie D, Simarro M, Sayos J, Guirado M, Sancho J, Terhorst C.
    Blood; 2002 Feb 01; 99(3):957-65. PubMed ID: 11806999
    [Abstract] [Full Text] [Related]

  • 8. Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation.
    Tangye SG, Nichols KE, Hare NJ, van de Weerdt BC.
    J Immunol; 2003 Sep 01; 171(5):2485-95. PubMed ID: 12928397
    [Abstract] [Full Text] [Related]

  • 9. Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.
    Lewis J, Eiben LJ, Nelson DL, Cohen JI, Nichols KE, Ochs HD, Notarangelo LD, Duckett CS.
    Clin Immunol; 2001 Jul 01; 100(1):15-23. PubMed ID: 11414741
    [Abstract] [Full Text] [Related]

  • 10. A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
    Hwang PM, Li C, Morra M, Lillywhite J, Muhandiram DR, Gertler F, Terhorst C, Kay LE, Pawson T, Forman-Kay JD, Li SC.
    EMBO J; 2002 Feb 01; 21(3):314-23. PubMed ID: 11823424
    [Abstract] [Full Text] [Related]

  • 11. NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site.
    Weber T, Schaffhausen B, Liu Y, Günther UL.
    Biochemistry; 2000 Dec 26; 39(51):15860-9. PubMed ID: 11123912
    [Abstract] [Full Text] [Related]

  • 12. Disease-causing SAP mutants are defective in ligand binding and protein folding.
    Li C, Iosef C, Jia CY, Gkourasas T, Han VK, Shun-Cheng Li S.
    Biochemistry; 2003 Dec 23; 42(50):14885-92. PubMed ID: 14674764
    [Abstract] [Full Text] [Related]

  • 13. Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem.
    Folmer RH, Geschwindner S, Xue Y.
    Biochemistry; 2002 Dec 03; 41(48):14176-84. PubMed ID: 12450381
    [Abstract] [Full Text] [Related]

  • 14. Correlation between dynamics and high affinity binding in an SH2 domain interaction.
    Kay LE, Muhandiram DR, Farrow NA, Aubin Y, Forman-Kay JD.
    Biochemistry; 1996 Jan 16; 35(2):361-8. PubMed ID: 8555205
    [Abstract] [Full Text] [Related]

  • 15. CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A.
    Shlapatska LM, Mikhalap SV, Berdova AG, Zelensky OM, Yun TJ, Nichols KE, Clark EA, Sidorenko SP.
    J Immunol; 2001 May 01; 166(9):5480-7. PubMed ID: 11313386
    [Abstract] [Full Text] [Related]

  • 16. Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation.
    Latour S, Roncagalli R, Chen R, Bakinowski M, Shi X, Schwartzberg PL, Davidson D, Veillette A.
    Nat Cell Biol; 2003 Feb 01; 5(2):149-54. PubMed ID: 12545173
    [Abstract] [Full Text] [Related]

  • 17. Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.
    Morra M, Lu J, Poy F, Martin M, Sayos J, Calpe S, Gullo C, Howie D, Rietdijk S, Thompson A, Coyle AJ, Denny C, Yaffe MB, Engel P, Eck MJ, Terhorst C.
    EMBO J; 2001 Nov 01; 20(21):5840-52. PubMed ID: 11689425
    [Abstract] [Full Text] [Related]

  • 18. Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase.
    Siegal G, Davis B, Kristensen SM, Sankar A, Linacre J, Stein RC, Panayotou G, Waterfield MD, Driscoll PC.
    J Mol Biol; 1998 Feb 20; 276(2):461-78. PubMed ID: 9512716
    [Abstract] [Full Text] [Related]

  • 19. Mutational investigation of the specificity determining region of the Src SH2 domain.
    Bradshaw JM, Mitaxov V, Waksman G.
    J Mol Biol; 2000 Jun 02; 299(2):521-35. PubMed ID: 10860756
    [Abstract] [Full Text] [Related]

  • 20. Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase.
    Bradshaw JM, Mitaxov V, Waksman G.
    J Mol Biol; 1999 Nov 05; 293(4):971-85. PubMed ID: 10543978
    [Abstract] [Full Text] [Related]

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