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Journal Abstract Search


295 related items for PubMed ID: 12225808

  • 1. Highly sulfated glycosaminoglycans inhibit aggrecanase degradation of aggrecan by bovine articular cartilage explant cultures.
    Munteanu SE, Ilic MZ, Handley CJ.
    Matrix Biol; 2002 Aug; 21(5):429-40. PubMed ID: 12225808
    [Abstract] [Full Text] [Related]

  • 2. Calcium pentosan polysulfate inhibits the catabolism of aggrecan in articular cartilage explant cultures.
    Munteanu SE, Ilic MZ, Handley CJ.
    Arthritis Rheum; 2000 Oct; 43(10):2211-8. PubMed ID: 11037880
    [Abstract] [Full Text] [Related]

  • 3. Effects of long-term exposure to glucosamine and mannosamine on aggrecan degradation in articular cartilage.
    Ilic MZ, Martinac B, Handley CJ.
    Osteoarthritis Cartilage; 2003 Aug; 11(8):613-22. PubMed ID: 12880584
    [Abstract] [Full Text] [Related]

  • 4. Catabolism of aggrecan by explant cultures of human articular cartilage in the presence of retinoic acid.
    Ilic MZ, Mok MT, Williamson OD, Campbell MA, Hughes CE, Handley CJ.
    Arch Biochem Biophys; 1995 Sep 10; 322(1):22-30. PubMed ID: 7574678
    [Abstract] [Full Text] [Related]

  • 5. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
    Little CB, Flannery CR, Hughes CE, Mort JS, Roughley PJ, Dent C, Caterson B.
    Biochem J; 1999 Nov 15; 344 Pt 1(Pt 1):61-8. PubMed ID: 10548534
    [Abstract] [Full Text] [Related]

  • 6. The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism.
    Sztrolovics R, White RJ, Roughley PJ, Mort JS.
    Biochem J; 2002 Mar 01; 362(Pt 2):465-72. PubMed ID: 11853556
    [Abstract] [Full Text] [Related]

  • 7. Distribution of newly synthesized aggrecan in explant cultures of bovine cartilage treated with retinoic acid.
    Handley CJ, Winter GM, Ilic MZ, Ross JM, Anthony Poole C, Clem Robinson H.
    Matrix Biol; 2002 Nov 01; 21(7):579-92. PubMed ID: 12475642
    [Abstract] [Full Text] [Related]

  • 8. Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage.
    Patwari P, Kurz B, Sandy JD, Grodzinsky AJ.
    Arch Biochem Biophys; 2000 Feb 01; 374(1):79-85. PubMed ID: 10640399
    [Abstract] [Full Text] [Related]

  • 9. Cathepsin D cleaves aggrecan at unique sites within the interglobular domain and chondroitin sulfate attachment regions that are also cleaved when cartilage is maintained at acid pH.
    Handley CJ, Mok MT, Ilic MZ, Adcocks C, Buttle DJ, Robinson HC.
    Matrix Biol; 2001 Dec 01; 20(8):543-53. PubMed ID: 11731271
    [Abstract] [Full Text] [Related]

  • 10. Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2).
    Chockalingam PS, Zeng W, Morris EA, Flannery CR.
    Arthritis Rheum; 2004 Sep 01; 50(9):2839-48. PubMed ID: 15457452
    [Abstract] [Full Text] [Related]

  • 11. Cyclosporin A inhibition of aggrecanase-mediated proteoglycan catabolism in articular cartilage.
    Little CB, Hughes CE, Curtis CL, Jones SA, Caterson B, Flannery CR.
    Arthritis Rheum; 2002 Jan 01; 46(1):124-9. PubMed ID: 11817583
    [Abstract] [Full Text] [Related]

  • 12. Glycosaminoglycan addition to proteoglycans by articular chondrocytes--evidence for core protein-specific pathways.
    Wong-Palms S, Plaas AH.
    Arch Biochem Biophys; 1995 Jun 01; 319(2):383-92. PubMed ID: 7786019
    [Abstract] [Full Text] [Related]

  • 13. Resistance of small leucine-rich repeat proteoglycans to proteolytic degradation during interleukin-1-stimulated cartilage catabolism.
    Sztrolovics R, White RJ, Poole AR, Mort JS, Roughley PJ.
    Biochem J; 1999 May 01; 339 ( Pt 3)(Pt 3):571-7. PubMed ID: 10215595
    [Abstract] [Full Text] [Related]

  • 14. The G1 domain of aggrecan released from porcine articular cartilage forms stable complexes with hyaluronan/link protein.
    Yasumoto T, Bird JL, Sugimoto K, Mason RM, Bayliss MT.
    Rheumatology (Oxford); 2003 Feb 01; 42(2):336-42. PubMed ID: 12595632
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors.
    Bonassar LJ, Sandy JD, Lark MW, Plaas AH, Frank EH, Grodzinsky AJ.
    Arch Biochem Biophys; 1997 Aug 15; 344(2):404-12. PubMed ID: 9264555
    [Abstract] [Full Text] [Related]

  • 16. Cytokine-induced cartilage proteoglycan degradation is mediated by aggrecanase.
    Arner EC, Hughes CE, Decicco CP, Caterson B, Tortorella MD.
    Osteoarthritis Cartilage; 1998 May 15; 6(3):214-28. PubMed ID: 9682788
    [Abstract] [Full Text] [Related]

  • 17. Kinetics of proteoglycan turnover in bovine articular cartilage explants.
    von den Hoff JW, van Kampen GP, van de Stadt RJ, van der Korst JK.
    Matrix; 1993 May 15; 13(3):195-201. PubMed ID: 8326910
    [Abstract] [Full Text] [Related]

  • 18. TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.
    Gendron C, Kashiwagi M, Hughes C, Caterson B, Nagase H.
    FEBS Lett; 2003 Dec 18; 555(3):431-6. PubMed ID: 14675751
    [Abstract] [Full Text] [Related]

  • 19. Changes in cartilage proteoglycan aggrecan after intra-articular injection of interleukin-1 in rabbits: studies of synovial fluid and articular cartilage.
    Lundberg C, Asberg I, Ionescu M, Reiner A, Smedegård G, Poole AR.
    Ann Rheum Dis; 1996 Aug 18; 55(8):525-34. PubMed ID: 8774180
    [Abstract] [Full Text] [Related]

  • 20. Cartilage degradation independent of MMP/aggrecanases.
    Sugimoto K, Iizawa T, Harada H, Yamada K, Katsumata M, Takahashi M.
    Osteoarthritis Cartilage; 2004 Dec 18; 12(12):1006-14. PubMed ID: 15564068
    [Abstract] [Full Text] [Related]


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