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353 related items for PubMed ID: 12234920

  • 1. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.
    Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR.
    EMBO J; 2002 Sep 16; 21(18):4796-808. PubMed ID: 12234920
    [Abstract] [Full Text] [Related]

  • 2. Evidence for direct interaction between Sprouty and Cbl.
    Wong ES, Lim J, Low BC, Chen Q, Guy GR.
    J Biol Chem; 2001 Feb 23; 276(8):5866-75. PubMed ID: 11053437
    [Abstract] [Full Text] [Related]

  • 3. Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function.
    Fong CW, Leong HF, Wong ES, Lim J, Yusoff P, Guy GR.
    J Biol Chem; 2003 Aug 29; 278(35):33456-64. PubMed ID: 12815057
    [Abstract] [Full Text] [Related]

  • 4. hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl.
    Hall AB, Jura N, DaSilva J, Jang YJ, Gong D, Bar-Sagi D.
    Curr Biol; 2003 Feb 18; 13(4):308-14. PubMed ID: 12593796
    [Abstract] [Full Text] [Related]

  • 5. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops.
    Rubin C, Litvak V, Medvedovsky H, Zwang Y, Lev S, Yarden Y.
    Curr Biol; 2003 Feb 18; 13(4):297-307. PubMed ID: 12593795
    [Abstract] [Full Text] [Related]

  • 6. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7.
    Yokouchi M, Kondo T, Houghton A, Bartkiewicz M, Horne WC, Zhang H, Yoshimura A, Baron R.
    J Biol Chem; 1999 Oct 29; 274(44):31707-12. PubMed ID: 10531381
    [Abstract] [Full Text] [Related]

  • 7. Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.
    Yusoff P, Lao DH, Ong SH, Wong ES, Lim J, Lo TL, Leong HF, Fong CW, Guy GR.
    J Biol Chem; 2002 Feb 01; 277(5):3195-201. PubMed ID: 11698404
    [Abstract] [Full Text] [Related]

  • 8. The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins.
    Egan JE, Hall AB, Yatsula BA, Bar-Sagi D.
    Proc Natl Acad Sci U S A; 2002 Apr 30; 99(9):6041-6. PubMed ID: 11983899
    [Abstract] [Full Text] [Related]

  • 9. Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.
    Haglund K, Schmidt MHH, Wong ES, Guy GR, Dikic I.
    EMBO Rep; 2005 Jul 30; 6(7):635-41. PubMed ID: 15962011
    [Abstract] [Full Text] [Related]

  • 10. Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.
    Huang F, Sorkin A.
    Mol Biol Cell; 2005 Mar 30; 16(3):1268-81. PubMed ID: 15635092
    [Abstract] [Full Text] [Related]

  • 11. Sprouty: how does the branch manager work?
    Guy GR, Wong ES, Yusoff P, Chandramouli S, Lo TL, Lim J, Fong CW.
    J Cell Sci; 2003 Aug 01; 116(Pt 15):3061-8. PubMed ID: 12829736
    [Abstract] [Full Text] [Related]

  • 12. Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.
    Jiang X, Sorkin A.
    Traffic; 2003 Aug 01; 4(8):529-43. PubMed ID: 12839496
    [Abstract] [Full Text] [Related]

  • 13. The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor.
    Lill NL, Douillard P, Awwad RA, Ota S, Lupher ML, Miyake S, Meissner-Lula N, Hsu VW, Band H.
    J Biol Chem; 2000 Jan 07; 275(1):367-77. PubMed ID: 10617627
    [Abstract] [Full Text] [Related]

  • 14. Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation.
    Sasaki A, Taketomi T, Wakioka T, Kato R, Yoshimura A.
    J Biol Chem; 2001 Sep 28; 276(39):36804-8. PubMed ID: 11495895
    [Abstract] [Full Text] [Related]

  • 15. Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.
    Chandramouli S, Yu CY, Yusoff P, Lao DH, Leong HF, Mizuno K, Guy GR.
    J Biol Chem; 2008 Jan 18; 283(3):1679-1691. PubMed ID: 17974561
    [Abstract] [Full Text] [Related]

  • 16. Regulator of epidermal growth factor signaling: Sprouty.
    Wong ES, Guy GR.
    Methods Mol Biol; 2006 Jan 18; 327():61-83. PubMed ID: 16780213
    [Abstract] [Full Text] [Related]

  • 17. c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route.
    de Melker AA, van der Horst G, Calafat J, Jansen H, Borst J.
    J Cell Sci; 2001 Jun 18; 114(Pt 11):2167-78. PubMed ID: 11493652
    [Abstract] [Full Text] [Related]

  • 18. Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop.
    Mason JM, Morrison DJ, Bassit B, Dimri M, Band H, Licht JD, Gross I.
    Mol Biol Cell; 2004 May 18; 15(5):2176-88. PubMed ID: 15004239
    [Abstract] [Full Text] [Related]

  • 19. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.
    Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama M, Saito N, Shibuya M, Yoshimura A.
    Nat Cell Biol; 2003 May 18; 5(5):427-32. PubMed ID: 12717443
    [Abstract] [Full Text] [Related]

  • 20. Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
    Duan L, Miura Y, Dimri M, Majumder B, Dodge IL, Reddi AL, Ghosh A, Fernandes N, Zhou P, Mullane-Robinson K, Rao N, Donoghue S, Rogers RA, Bowtell D, Naramura M, Gu H, Band V, Band H.
    J Biol Chem; 2003 Aug 01; 278(31):28950-60. PubMed ID: 12754251
    [Abstract] [Full Text] [Related]

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