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830 related items for PubMed ID: 12234984

  • 1. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
    Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S.
    Cancer Res; 2002 Sep 15; 62(18):5196-203. PubMed ID: 12234984
    [Abstract] [Full Text] [Related]

  • 2. Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray.
    Hu R, Xu C, Shen G, Jain MR, Khor TO, Gopalkrishnan A, Lin W, Reddy B, Chan JY, Kong AN.
    Life Sci; 2006 Oct 12; 79(20):1944-55. PubMed ID: 16828809
    [Abstract] [Full Text] [Related]

  • 3. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW.
    Mol Med; 2001 Feb 12; 7(2):135-45. PubMed ID: 11471548
    [Abstract] [Full Text] [Related]

  • 4. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M, Itoh K, Yamamoto M, Chanas SA, Henderson CJ, McLellan LI, Wolf CR, Cavin C, Hayes JD.
    Cancer Res; 2001 Apr 15; 61(8):3299-307. PubMed ID: 11309284
    [Abstract] [Full Text] [Related]

  • 5. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
    Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW.
    Proc Natl Acad Sci U S A; 2001 Mar 13; 98(6):3410-5. PubMed ID: 11248092
    [Abstract] [Full Text] [Related]

  • 6. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element.
    Jowsey IR, Jiang Q, Itoh K, Yamamoto M, Hayes JD.
    Mol Pharmacol; 2003 Nov 13; 64(5):1018-28. PubMed ID: 14573750
    [Abstract] [Full Text] [Related]

  • 7. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
    Higgins LG, Cavin C, Itoh K, Yamamoto M, Hayes JD.
    Toxicol Appl Pharmacol; 2008 Feb 01; 226(3):328-37. PubMed ID: 18028974
    [Abstract] [Full Text] [Related]

  • 8. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates.
    McWalter GK, Higgins LG, McLellan LI, Henderson CJ, Song L, Thornalley PJ, Itoh K, Yamamoto M, Hayes JD.
    J Nutr; 2004 Dec 01; 134(12 Suppl):3499S-3506S. PubMed ID: 15570060
    [Abstract] [Full Text] [Related]

  • 9. Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
    Hu R, Xu C, Shen G, Jain MR, Khor TO, Gopalkrishnan A, Lin W, Reddy B, Chan JY, Kong AN.
    Cancer Lett; 2006 Nov 18; 243(2):170-92. PubMed ID: 16516379
    [Abstract] [Full Text] [Related]

  • 10. Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis.
    Iida K, Itoh K, Kumagai Y, Oyasu R, Hattori K, Kawai K, Shimazui T, Akaza H, Yamamoto M.
    Cancer Res; 2004 Sep 15; 64(18):6424-31. PubMed ID: 15374950
    [Abstract] [Full Text] [Related]

  • 11. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence.
    Nioi P, McMahon M, Itoh K, Yamamoto M, Hayes JD.
    Biochem J; 2003 Sep 01; 374(Pt 2):337-48. PubMed ID: 12816537
    [Abstract] [Full Text] [Related]

  • 12. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis.
    Lee JM, Calkins MJ, Chan K, Kan YW, Johnson JA.
    J Biol Chem; 2003 Apr 04; 278(14):12029-38. PubMed ID: 12556532
    [Abstract] [Full Text] [Related]

  • 13. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
    Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, Nabeshima Y.
    Biochem Biophys Res Commun; 1997 Jul 18; 236(2):313-22. PubMed ID: 9240432
    [Abstract] [Full Text] [Related]

  • 14. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury.
    Zhu H, Itoh K, Yamamoto M, Zweier JL, Li Y.
    FEBS Lett; 2005 Jun 06; 579(14):3029-36. PubMed ID: 15896789
    [Abstract] [Full Text] [Related]

  • 15. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
    Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    J Biol Chem; 2003 Mar 07; 278(10):8135-45. PubMed ID: 12506115
    [Abstract] [Full Text] [Related]

  • 16. Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene.
    Jeyapaul J, Jaiswal AK.
    Biochem Pharmacol; 2000 Jun 01; 59(11):1433-9. PubMed ID: 10751553
    [Abstract] [Full Text] [Related]

  • 17. Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin.
    Shen G, Xu C, Hu R, Jain MR, Gopalkrishnan A, Nair S, Huang MT, Chan JY, Kong AN.
    Mol Cancer Ther; 2006 Jan 01; 5(1):39-51. PubMed ID: 16432161
    [Abstract] [Full Text] [Related]

  • 18. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes.
    Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T, O'Connor T, Harada T, Yamamoto M.
    Toxicol Sci; 2001 Jan 01; 59(1):169-77. PubMed ID: 11134556
    [Abstract] [Full Text] [Related]

  • 19. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones.
    Pietsch EC, Chan JY, Torti FM, Torti SV.
    J Biol Chem; 2003 Jan 24; 278(4):2361-9. PubMed ID: 12435735
    [Abstract] [Full Text] [Related]

  • 20. Nrf2 as a novel molecular target for chemoprevention.
    Lee JS, Surh YJ.
    Cancer Lett; 2005 Jun 28; 224(2):171-84. PubMed ID: 15914268
    [Abstract] [Full Text] [Related]

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