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Journal Abstract Search

262 related items for PubMed ID: 12235837

  • 1. [Beta-amyloid protein: recent progress in basic research and therapeutic approaches].
    Iwatsubo T.
    Rinsho Shinkeigaku; 2001 Dec; 41(12):1198-200. PubMed ID: 12235837
    [Abstract] [Full Text] [Related]

  • 2. [The mechanism of A beta production and its inhibition as a therapeutic strategy for the prevention of Alzheimer's disease].
    Iwatsubo T.
    Nihon Yakurigaku Zasshi; 2002 Nov; 120(1):30P-33P. PubMed ID: 12491772
    [Abstract] [Full Text] [Related]

  • 3. [beta-amyloid cascade: current status and future directions].
    Iwatsubo T.
    Rinsho Shinkeigaku; 2000 Dec; 40(12):1228-30. PubMed ID: 11464463
    [Abstract] [Full Text] [Related]

  • 4. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
    [Abstract] [Full Text] [Related]

  • 5. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B.
    J Neurochem; 2006 Feb 01; 96(3):732-42. PubMed ID: 16405513
    [Abstract] [Full Text] [Related]

  • 6. Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins.
    Steiner H, Winkler E, Shearman MS, Prywes R, Haass C.
    Neurobiol Dis; 2001 Aug 01; 8(4):717-22. PubMed ID: 11493036
    [Abstract] [Full Text] [Related]

  • 7. [Advances in molecular biology and clinical study of amyloid precursor protein for Alzheimer's disease].
    Xu BG, Wu X.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Apr 01; 26(2):201-9. PubMed ID: 15171563
    [Abstract] [Full Text] [Related]

  • 8. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC, Hudson M, Kanning KC, Schecterson LC, Bothwell M.
    J Neurochem; 2005 Sep 01; 94(5):1189-201. PubMed ID: 15992373
    [Abstract] [Full Text] [Related]

  • 9. Presenilin, Notch, and the genesis and treatment of Alzheimer's disease.
    Selkoe DJ.
    Proc Natl Acad Sci U S A; 2001 Sep 25; 98(20):11039-41. PubMed ID: 11572965
    [Abstract] [Full Text] [Related]

  • 10. Alzheimer's disease. Molecular consequences of presenilin-1 mutation.
    Gandy S, Naslund J, Nordstedt C.
    Nature; 2001 Jun 07; 411(6838):654-6. PubMed ID: 11395757
    [Abstract] [Full Text] [Related]

  • 11. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
    Li YM, Xu M, Lai MT, Huang Q, Castro JL, DiMuzio-Mower J, Harrison T, Lellis C, Nadin A, Neduvelil JG, Register RB, Sardana MK, Shearman MS, Smith AL, Shi XP, Yin KC, Shafer JA, Gardell SJ.
    Nature; 2000 Jun 08; 405(6787):689-94. PubMed ID: 10864326
    [Abstract] [Full Text] [Related]

  • 12. Presenilin function and gamma-secretase activity.
    Brunkan AL, Goate AM.
    J Neurochem; 2005 May 08; 93(4):769-92. PubMed ID: 15857382
    [Abstract] [Full Text] [Related]

  • 13. [Alzheimer's disease: focus on beta-amyloid and gamma-secretase].
    Iwatsubo T.
    Tanpakushitsu Kakusan Koso; 2004 May 08; 49(7 Suppl):1086-90. PubMed ID: 15168534
    [No Abstract] [Full Text] [Related]

  • 14. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
    Barten DM, Guss VL, Corsa JA, Loo A, Hansel SB, Zheng M, Munoz B, Srinivasan K, Wang B, Robertson BJ, Polson CT, Wang J, Roberts SB, Hendrick JP, Anderson JJ, Loy JK, Denton R, Verdoorn TA, Smith DW, Felsenstein KM.
    J Pharmacol Exp Ther; 2005 Feb 08; 312(2):635-43. PubMed ID: 15452193
    [Abstract] [Full Text] [Related]

  • 15. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.
    Mol Vis; 2003 May 01; 9():179-83. PubMed ID: 12740567
    [Abstract] [Full Text] [Related]

  • 16. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA.
    Luo HM, Deng H, Xiao F, Gao Q, Weng W, Zhang PF, Li XG.
    Acta Pharmacol Sin; 2004 Dec 01; 25(12):1613-8. PubMed ID: 15569405
    [Abstract] [Full Text] [Related]

  • 17. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
    Iwatsubo T.
    Rinsho Shinkeigaku; 2004 Nov 01; 44(11):768-70. PubMed ID: 15651286
    [Abstract] [Full Text] [Related]

  • 18. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice.
    Tournoy J, Bossuyt X, Snellinx A, Regent M, Garmyn M, Serneels L, Saftig P, Craessaerts K, De Strooper B, Hartmann D.
    Hum Mol Genet; 2004 Jul 01; 13(13):1321-31. PubMed ID: 15128703
    [Abstract] [Full Text] [Related]

  • 19. Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments.
    Vetrivel KS, Thinakaran G.
    Neurology; 2006 Jan 24; 66(2 Suppl 1):S69-73. PubMed ID: 16432149
    [Abstract] [Full Text] [Related]

  • 20. Alzheimer's disease. Closing in on gamma-secretase.
    De Strooper B.
    Nature; 2000 Jun 08; 405(6787):627, 629. PubMed ID: 10864307
    [No Abstract] [Full Text] [Related]

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