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Journal Abstract Search


406 related items for PubMed ID: 12237780

  • 1. Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy.
    Martínez C, García-Martín E, Pizarro RM, García-Gamito FJ, Agúndez JA.
    Br J Cancer; 2002 Sep 09; 87(6):681-6. PubMed ID: 12237780
    [Abstract] [Full Text] [Related]

  • 2. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 09; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

  • 3. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes.
    Zhu M, Zhao W, Jimenez H, Zhang D, Yeola S, Dai R, Vachharajani N, Mitroka J.
    Drug Metab Dispos; 2005 Apr 09; 33(4):500-7. PubMed ID: 15640381
    [Abstract] [Full Text] [Related]

  • 4. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation.
    Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD.
    J Pharmacol Exp Ther; 1999 Sep 09; 290(3):1116-25. PubMed ID: 10454485
    [Abstract] [Full Text] [Related]

  • 5. Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.
    Voorman RL, Maio SM, Payne NA, Zhao Z, Koeplinger KA, Wang X.
    J Pharmacol Exp Ther; 1998 Oct 09; 287(1):381-8. PubMed ID: 9765359
    [Abstract] [Full Text] [Related]

  • 6. Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.
    Tsunoda SM, Velez RL, von Moltke LL, Greenblatt DJ.
    Clin Pharmacol Ther; 1999 Nov 09; 66(5):461-71. PubMed ID: 10579473
    [Abstract] [Full Text] [Related]

  • 7. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions.
    Zhou-Pan XR, Sérée E, Zhou XJ, Placidi M, Maurel P, Barra Y, Rahmani R.
    Cancer Res; 1993 Nov 01; 53(21):5121-6. PubMed ID: 8221648
    [Abstract] [Full Text] [Related]

  • 8. Antitumor activity of methoxymorpholinyl doxorubicin: potentiation by cytochrome P450 3A metabolism.
    Lu H, Waxman DJ.
    Mol Pharmacol; 2005 Jan 01; 67(1):212-9. PubMed ID: 15465924
    [Abstract] [Full Text] [Related]

  • 9. Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
    Ekström G, Gunnarsson UB.
    Drug Metab Dispos; 1996 Sep 01; 24(9):955-61. PubMed ID: 8886604
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.
    Haaz MC, Rivory L, Riché C, Vernillet L, Robert J.
    Cancer Res; 1998 Feb 01; 58(3):468-72. PubMed ID: 9458091
    [Abstract] [Full Text] [Related]

  • 11. The use of human hepatocyte cultures to study the induction of cytochrome P-450.
    Kostrubsky VE, Ramachandran V, Venkataramanan R, Dorko K, Esplen JE, Zhang S, Sinclair JF, Wrighton SA, Strom SC.
    Drug Metab Dispos; 1999 Aug 01; 27(8):887-94. PubMed ID: 10421615
    [Abstract] [Full Text] [Related]

  • 12. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
    Zhang Y, Guo X, Lin ET, Benet LZ.
    Drug Metab Dispos; 1998 Apr 01; 26(4):360-6. PubMed ID: 9531525
    [Abstract] [Full Text] [Related]

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  • 14. Tolterodine, a new muscarinic receptor antagonist, is metabolized by cytochromes P450 2D6 and 3A in human liver microsomes.
    Postlind H, DanielsonA, Lindgren A, Andersson SH.
    Drug Metab Dispos; 1998 Apr 01; 26(4):289-93. PubMed ID: 9531513
    [Abstract] [Full Text] [Related]

  • 15. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
    Pearce RE, Gotschall RR, Kearns GL, Leeder JS.
    Drug Metab Dispos; 2001 Dec 01; 29(12):1548-54. PubMed ID: 11717173
    [Abstract] [Full Text] [Related]

  • 16. Both cytochromes P450 2E1 and 3A are involved in the O-hydroxylation of p-nitrophenol, a catalytic activity known to be specific for P450 2E1.
    Zerilli A, Ratanasavanh D, Lucas D, Goasduff T, Dréano Y, Menard C, Picart D, Berthou F.
    Chem Res Toxicol; 1997 Oct 01; 10(10):1205-12. PubMed ID: 9348445
    [Abstract] [Full Text] [Related]

  • 17. Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions.
    Fabre G, Julian B, Saint-Aubert B, Joyeux H, Berger Y.
    Drug Metab Dispos; 1993 Oct 01; 21(6):978-85. PubMed ID: 7905403
    [Abstract] [Full Text] [Related]

  • 18. The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite.
    Fischer V, Rodríguez-Gascón A, Heitz F, Tynes R, Hauck C, Cohen D, Vickers AE.
    Drug Metab Dispos; 1998 Aug 01; 26(8):802-11. PubMed ID: 9698296
    [Abstract] [Full Text] [Related]

  • 19. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
    Quintieri L, Rosato A, Napoli E, Sola F, Geroni C, Floreani M, Zanovello P.
    Cancer Res; 2000 Jun 15; 60(12):3232-8. PubMed ID: 10866316
    [Abstract] [Full Text] [Related]

  • 20. Properties and regional expression of a CYP3A-like protein in channel catfish intestine.
    James MO, Lou Z, Rowland-Faux L, Celander MC.
    Aquat Toxicol; 2005 May 15; 72(4):361-71. PubMed ID: 15848255
    [Abstract] [Full Text] [Related]


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