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Journal Abstract Search

124 related items for PubMed ID: 12239087

  • 1. Thyrotropin, follitropin, and chorionic gonadotropin expressed as a single multifunctional unit reveal remarkable permissiveness in receptor-ligand interactions.
    Garcia-Campayo V, Kumar TR, Boime I.
    Endocrinology; 2002 Oct; 143(10):3773-8. PubMed ID: 12239087
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  • 2. Genetic fusion of an alpha-subunit gene to the follicle-stimulating hormone and chorionic gonadotropin-beta subunit genes: production of a bifunctional protein.
    Kanda M, Jablonka-Shariff A, Sato A, Pixley MR, Bos E, Hiro'oka T, Ben-Menahem D, Boime I.
    Mol Endocrinol; 1999 Nov; 13(11):1873-81. PubMed ID: 10551781
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  • 3. Single-chain, triple-domain gonadotropin analogs with disulfide bond mutations in the alpha-subunit elicit dual follitropin and lutropin activities in vivo.
    Jablonka-Shariff A, Kumar TR, Eklund J, Comstock A, Boime I.
    Mol Endocrinol; 2006 Jun; 20(6):1437-46. PubMed ID: 16601070
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  • 4. A single-chain tetradomain glycoprotein hormone analog elicits multiple hormone activities in vivo.
    Garcia-Campayo V, Boime I, Ma X, Daphna-Iken D, Kumar TR.
    Biol Reprod; 2005 Feb; 72(2):301-8. PubMed ID: 15385421
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  • 5. Synthesis of multi-subunit domain gonadotropin complexes: a model for alpha/beta heterodimer formation.
    Ben-Menahem D, Hyde R, Pixley M, Berger P, Boime I.
    Biochemistry; 1999 Nov 16; 38(46):15070-7. PubMed ID: 10563789
    [Abstract] [Full Text] [Related]

  • 6. The position of the alpha and beta subunits in a single chain variant of human chorionic gonadotropin affects the heterodimeric interaction of the subunits and receptor-binding epitopes.
    Ben-Menahem D, Jablonka-Shariff A, Hyde RK, Pixley MR, Srivastava S, Berger P, Boime I.
    J Biol Chem; 2001 Aug 10; 276(32):29871-9. PubMed ID: 11390409
    [Abstract] [Full Text] [Related]

  • 7. Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common alpha-subunit: retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG.
    Furuhashi M, Shikone T, Fares FA, Sugahara T, Hsueh AJ, Boime I.
    Mol Endocrinol; 1995 Jan 10; 9(1):54-63. PubMed ID: 7539107
    [Abstract] [Full Text] [Related]

  • 8. A single-chain bifunctional gonadotropin analog is secreted from Chinese hamster ovary cells as two distinct bioactive species.
    Garcia-Campayo V, Jablonka-Shariff A, Boime I.
    J Biol Chem; 2004 Oct 22; 279(43):44286-93. PubMed ID: 15308629
    [Abstract] [Full Text] [Related]

  • 9. Conversion of thyrotropin heterodimer to a biologically active single-chain.
    Fares FA, Yamabe S, Ben-Menahem D, Pixley M, Hsueh AJ, Boime I.
    Endocrinology; 1998 May 22; 139(5):2459-64. PubMed ID: 9564858
    [Abstract] [Full Text] [Related]

  • 10. Independent activities of FSH and LH structurally confined in a single polypeptide: selective modification of the relative potencies of the hormones.
    Garcia-Campayo V, Boime I.
    Endocrinology; 2001 Dec 22; 142(12):5203-11. PubMed ID: 11713216
    [Abstract] [Full Text] [Related]

  • 11. Site-directed mutagenesis of amino acids 33-44 of the common alpha-subunit reveals different structural requirements for heterodimer expression among the glycoprotein hormones and suggests that cyclic adenosine 3',5'-monophosphate production and growth promotion are potentially dissociable functions of human thyrotropin.
    Grossmann M, Szkudlinski MW, Dias JA, Xia H, Wong R, Puett D, Weintraub BD.
    Mol Endocrinol; 1996 Jun 22; 10(6):769-79. PubMed ID: 8776737
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  • 17. The gonadotropin genes: evolution of distinct mechanisms for hormonal control.
    Albanese C, Colin IM, Crowley WF, Ito M, Pestell RG, Weiss J, Jameson JL.
    Recent Prog Horm Res; 1996 Jun 22; 51():23-58; discussion 59-61. PubMed ID: 8701081
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  • 19. Specificity of cognate ligand-receptor interactions: fusion proteins of human chorionic gonadotropin and the heptahelical receptors for human luteinizing hormone, thyroid-stimulating hormone, and follicle-stimulating hormone.
    Schubert RL, Narayan P, Puett D.
    Endocrinology; 2003 Jan 22; 144(1):129-37. PubMed ID: 12488338
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