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Journal Abstract Search

1056 related items for PubMed ID: 12242151

  • 1. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
    Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ.
    Cancer Cell; 2002 Sep; 2(3):183-92. PubMed ID: 12242151
    [Abstract] [Full Text] [Related]

  • 2. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 3. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.
    Mol Cell; 2001 Sep 07; 8(3):705-11. PubMed ID: 11583631
    [Abstract] [Full Text] [Related]

  • 4. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 5. Direct addition of BimL to mitochondria does not lead to cytochrome c release.
    Terradillos O, Montessuit S, Huang DC, Martinou JC.
    FEBS Lett; 2002 Jul 03; 522(1-3):29-34. PubMed ID: 12095614
    [Abstract] [Full Text] [Related]

  • 6. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD.
    Mol Cell; 2005 Feb 18; 17(4):525-35. PubMed ID: 15721256
    [Abstract] [Full Text] [Related]

  • 7. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
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  • 10. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 23; 8(12):1348-58. PubMed ID: 17115033
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  • 11. A role for mitochondrial Bak in apoptotic response to anticancer drugs.
    Wang GQ, Gastman BR, Wieckowski E, Goldstein LA, Gambotto A, Kim TH, Fang B, Rabinovitz A, Yin XM, Rabinowich H.
    J Biol Chem; 2001 Sep 07; 276(36):34307-17. PubMed ID: 11447222
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  • 13. Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death.
    Shangary S, Johnson DE.
    Biochemistry; 2002 Jul 30; 41(30):9485-95. PubMed ID: 12135371
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  • 15. Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
    Wang GQ, Wieckowski E, Goldstein LA, Gastman BR, Rabinovitz A, Gambotto A, Li S, Fang B, Yin XM, Rabinowich H.
    J Exp Med; 2001 Nov 05; 194(9):1325-37. PubMed ID: 11696597
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  • 16. Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells.
    Shimizu S, Matsuoka Y, Shinohara Y, Yoneda Y, Tsujimoto Y.
    J Cell Biol; 2001 Jan 22; 152(2):237-50. PubMed ID: 11266442
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  • 17. Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity.
    Shimizu S, Tsujimoto Y.
    Proc Natl Acad Sci U S A; 2000 Jan 18; 97(2):577-82. PubMed ID: 10639121
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  • 18. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak.
    Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB.
    Genes Dev; 2001 Jun 15; 15(12):1481-6. PubMed ID: 11410528
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  • 19. Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.
    Yamaguchi H, Wang HG.
    J Biol Chem; 2002 Nov 01; 277(44):41604-12. PubMed ID: 12198137
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  • 20. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 01; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

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