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222 related items for PubMed ID: 12297295

  • 1. Direct identification of PTEN phosphorylation sites.
    Miller SJ, Lou DY, Seldin DC, Lane WS, Neel BG.
    FEBS Lett; 2002 Sep 25; 528(1-3):145-53. PubMed ID: 12297295
    [Abstract] [Full Text] [Related]

  • 2. The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation.
    Torres J, Pulido R.
    J Biol Chem; 2001 Jan 12; 276(2):993-8. PubMed ID: 11035045
    [Abstract] [Full Text] [Related]

  • 3. Cilostazol enhances casein kinase 2 phosphorylation and suppresses tumor necrosis factor-alpha-induced increased phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and apoptotic cell death in SK-N-SH cells.
    Kim KY, Shin HK, Lee JH, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW.
    J Pharmacol Exp Ther; 2004 Jan 12; 308(1):97-104. PubMed ID: 14569058
    [Abstract] [Full Text] [Related]

  • 4. Anti-apoptotic action of (2S,3S,4R)-N"-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378) by suppression of the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and increased phosphorylation of casein kinase2/Akt/ cyclic AMP response element binding protein via maxi-K channel opening in neuronal cells.
    Kim KY, Lee JH, Park JH, Yoo MA, Kwak YG, Kim SO, Yoo SE, Hong KW.
    Eur J Pharmacol; 2004 Aug 30; 497(3):267-77. PubMed ID: 15336944
    [Abstract] [Full Text] [Related]

  • 5. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
    Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.
    J Biol Chem; 2003 Oct 10; 278(41):40057-66. PubMed ID: 12869565
    [Abstract] [Full Text] [Related]

  • 6. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME, Gagnon V, Mathieu I, Parent S, Asselin E.
    Int J Oncol; 2004 May 10; 24(5):1311-24. PubMed ID: 15067356
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
    Edwards LA, Thiessen B, Dragowska WH, Daynard T, Bally MB, Dedhar S.
    Oncogene; 2005 May 19; 24(22):3596-605. PubMed ID: 15782140
    [Abstract] [Full Text] [Related]

  • 8. Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions.
    Torres J, Rodriguez J, Myers MP, Valiente M, Graves JD, Tonks NK, Pulido R.
    J Biol Chem; 2003 Aug 15; 278(33):30652-60. PubMed ID: 12788938
    [Abstract] [Full Text] [Related]

  • 9. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR.
    Proc Natl Acad Sci U S A; 1999 Mar 02; 96(5):2110-5. PubMed ID: 10051603
    [Abstract] [Full Text] [Related]

  • 10. Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.
    Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA.
    Cancer Res; 1998 Dec 01; 58(23):5285-90. PubMed ID: 9850049
    [Abstract] [Full Text] [Related]

  • 11. Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.
    Gu J, Tamura M, Yamada KM.
    J Cell Biol; 1998 Nov 30; 143(5):1375-83. PubMed ID: 9832564
    [Abstract] [Full Text] [Related]

  • 12. Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.
    Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP.
    Biochem J; 2001 Jul 15; 357(Pt 2):427-35. PubMed ID: 11439092
    [Abstract] [Full Text] [Related]

  • 13. A surprising function for the PTEN tumor suppressor.
    Hopkin K.
    Science; 1998 Nov 06; 282(5391):1027,1029-30. PubMed ID: 9841444
    [No Abstract] [Full Text] [Related]

  • 14. The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase.
    Wang X, Gjörloff-Wingren A, Saxena M, Pathan N, Reed JC, Mustelin T.
    J Immunol; 2000 Feb 15; 164(4):1934-9. PubMed ID: 10657643
    [Abstract] [Full Text] [Related]

  • 15. Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta.
    Al-Khouri AM, Ma Y, Togo SH, Williams S, Mustelin T.
    J Biol Chem; 2005 Oct 21; 280(42):35195-202. PubMed ID: 16107342
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.
    Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, Dedhar S.
    Proc Natl Acad Sci U S A; 2000 Mar 28; 97(7):3207-12. PubMed ID: 10716737
    [Abstract] [Full Text] [Related]

  • 17. Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.
    Koul D, Jasser SA, Lu Y, Davies MA, Shen R, Shi Y, Mills GB, Yung WK.
    Oncogene; 2002 Apr 04; 21(15):2357-64. PubMed ID: 11948419
    [Abstract] [Full Text] [Related]

  • 18. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
    [Abstract] [Full Text] [Related]

  • 19. PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1.
    Bruni P, Boccia A, Baldassarre G, Trapasso F, Santoro M, Chiappetta G, Fusco A, Viglietto G.
    Oncogene; 2000 Jun 29; 19(28):3146-55. PubMed ID: 10918569
    [Abstract] [Full Text] [Related]

  • 20. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells.
    Li DM, Sun H.
    Proc Natl Acad Sci U S A; 1998 Dec 22; 95(26):15406-11. PubMed ID: 9860981
    [Abstract] [Full Text] [Related]

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