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102 related items for PubMed ID: 12353074

  • 1. Reduced factor V concentration and altered FV1/FV2 ratio do not fully explain R2-associated APC-resistance.
    Govers-Riemslag JW, Castoldi E, Nicolaes GA, Tans G, Rosing J.
    Thromb Haemost; 2002 Sep; 88(3):444-9. PubMed ID: 12353074
    [Abstract] [Full Text] [Related]

  • 2. Functional properties of factor V and factor Va encoded by the R2-gene.
    Hoekema L, Castoldi E, Tans G, Girelli D, Gemmati D, Bernardi F, Rosing J.
    Thromb Haemost; 2001 Jan; 85(1):75-81. PubMed ID: 11204592
    [Abstract] [Full Text] [Related]

  • 3. An assay to quantify the two plasma isoforms of factor V.
    Hoekema L, Rosing J, Tans G.
    Thromb Haemost; 2000 Dec; 84(6):1066-71. PubMed ID: 11154115
    [Abstract] [Full Text] [Related]

  • 4. Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPIα: Difference between FV1 and FV2.
    van Doorn P, Rosing J, Duckers C, Hackeng TM, Simioni P, Castoldi E.
    Thromb Haemost; 2018 Jul; 118(7):1194-1202. PubMed ID: 29864781
    [Abstract] [Full Text] [Related]

  • 5. Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation.
    Brugge JM, Simioni P, Bernardi F, Tormene D, Lunghi B, Tans G, Pagnan A, Rosing J, Castoldi E.
    J Thromb Haemost; 2005 Dec; 3(12):2695-702. PubMed ID: 16359508
    [Abstract] [Full Text] [Related]

  • 6. The R2-haplotype associated Asp2194Gly mutation in the light chain of human factor V results in lower expression levels of FV, but has no influence on the glycosylation of Asn2181.
    van der Neut Kolfschoten M, Dirven RJ, Vos HL, Bertina RM.
    Thromb Haemost; 2003 Mar; 89(3):429-37. PubMed ID: 12624624
    [Abstract] [Full Text] [Related]

  • 7. Determination of activated protein C resistance in anticoagulated and lupus positive patients.
    Ivey LM, Thom JY, Ivey JG, Baker RI.
    Blood Coagul Fibrinolysis; 2000 Jul; 11(5):439-45. PubMed ID: 10937805
    [Abstract] [Full Text] [Related]

  • 8. Mutations in the R2 FV gene affect the ratio between the two FV isoforms in plasma.
    Castoldi E, Rosing J, Girelli D, Hoekema L, Lunghi B, Mingozzi F, Ferraresi P, Friso S, Corrocher R, Tans G, Bernardi F.
    Thromb Haemost; 2000 Mar; 83(3):362-5. PubMed ID: 10744138
    [Abstract] [Full Text] [Related]

  • 9. Factor V is an anticoagulant cofactor for activated protein C during inactivation of factor Va.
    Cramer TJ, Griffin JH, Gale AJ.
    Pathophysiol Haemost Thromb; 2010 Mar; 37(1):17-23. PubMed ID: 20501981
    [Abstract] [Full Text] [Related]

  • 10. Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations.
    Castoldi E, Brugge JM, Nicolaes GA, Girelli D, Tans G, Rosing J.
    Blood; 2004 Jun 01; 103(11):4173-9. PubMed ID: 14976057
    [Abstract] [Full Text] [Related]

  • 11. The impact of oral anticoagulant therapy, factor VIII level and quality of factor V-deficient plasma on three commercial methods for activated protein C resistance.
    Chitolie A, Lawrie AS, Mackie IJ, Harrison P, Machin SJ.
    Blood Coagul Fibrinolysis; 2001 Apr 01; 12(3):179-86. PubMed ID: 11414631
    [Abstract] [Full Text] [Related]

  • 12. Molecular mechanisms of activated protein C resistance. Properties of factor V isolated from an individual with homozygosity for the Arg506 to Gln mutation in the factor V gene.
    Aparicio C, Dahlbäck B.
    Biochem J; 1996 Jan 15; 313 ( Pt 2)(Pt 2):467-72. PubMed ID: 8573079
    [Abstract] [Full Text] [Related]

  • 13. Genetic modulation of the FV(Leiden)/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes.
    Segers O, Simioni P, Tormene D, Bulato C, Gavasso S, Rosing J, Castoldi E.
    J Thromb Haemost; 2012 Jan 15; 10(1):73-80. PubMed ID: 22044617
    [Abstract] [Full Text] [Related]

  • 14. Activated protein C resistance and thrombosis: molecular mechanisms of hypercoagulable state due to FVR506Q mutation.
    Dahlbäck B.
    Semin Thromb Hemost; 1999 Jan 15; 25(3):273-89. PubMed ID: 10443959
    [Abstract] [Full Text] [Related]

  • 15. [Comparison of three reactants for the detection of activated protein C resistance due to mutation of factor V Leiden during pregnancy].
    Magdelaine A, Soubrier F, Berkane N, Uzan S, Verdy E.
    Ann Biol Clin (Paris); 1998 Jan 15; 56(4):445-50. PubMed ID: 9754280
    [Abstract] [Full Text] [Related]

  • 16. Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V.
    Heeb MJ, Kojima Y, Greengard JS, Griffin JH.
    Blood; 1995 Jun 15; 85(12):3405-11. PubMed ID: 7780127
    [Abstract] [Full Text] [Related]

  • 17. The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model.
    van der Neut Kolfschoten M, Dirven RJ, Tans G, Rosing J, Vos HL, Bertina RM.
    Blood Coagul Fibrinolysis; 2002 Apr 15; 13(3):207-15. PubMed ID: 11943934
    [Abstract] [Full Text] [Related]

  • 18. The HR2 haplotype of factor V: effects on factor V levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis.
    de Visser MC, Guasch JF, Kamphuisen PW, Vos HL, Rosendaal FR, Bertina RM.
    Thromb Haemost; 2000 Apr 15; 83(4):577-82. PubMed ID: 10780320
    [Abstract] [Full Text] [Related]

  • 19. Plasma homocysteine concentration is not associated with activated protein C resistance in patients investigated for hypercoagulability.
    Zarychanski R, Houston DS.
    Thromb Haemost; 2004 Jun 15; 91(6):1115-22. PubMed ID: 15175797
    [Abstract] [Full Text] [Related]

  • 20. Functional characterization of recombinant FV Hong Kong and FV Cambridge.
    Norstrøm E, Thorelli E, Dahlbäck B.
    Blood; 2002 Jul 15; 100(2):524-30. PubMed ID: 12091344
    [Abstract] [Full Text] [Related]

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