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241 related items for PubMed ID: 12354780

  • 1. PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.
    Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M.
    Hum Mol Genet; 2002 Oct 01; 11(21):2547-58. PubMed ID: 12354780
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  • 3. Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
    Huang CC, Faber PW, Persichetti F, Mittal V, Vonsattel JP, MacDonald ME, Gusella JF.
    Somat Cell Mol Genet; 1998 Jul 01; 24(4):217-33. PubMed ID: 10410676
    [Abstract] [Full Text] [Related]

  • 4. Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin.
    Bao J, Sharp AH, Wagster MV, Becher M, Schilling G, Ross CA, Dawson VL, Dawson TM.
    Proc Natl Acad Sci U S A; 1996 May 14; 93(10):5037-42. PubMed ID: 8643525
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  • 5. Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.
    Sayer JA, Manczak M, Akileswaran L, Reddy PH, Coghlan VM.
    Neuromolecular Med; 2005 May 14; 7(4):297-310. PubMed ID: 16391387
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  • 6. Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.
    Chun W, Lesort M, Tucholski J, Faber PW, MacDonald ME, Ross CA, Johnson GV.
    Neurobiol Dis; 2001 Jun 14; 8(3):391-404. PubMed ID: 11442349
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  • 7. Huntingtin contains a highly conserved nuclear export signal.
    Xia J, Lee DH, Taylor J, Vandelft M, Truant R.
    Hum Mol Genet; 2003 Jun 15; 12(12):1393-403. PubMed ID: 12783847
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  • 8. Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin.
    Cyr M, Sotnikova TD, Gainetdinov RR, Caron MG.
    FASEB J; 2006 Dec 15; 20(14):2541-3. PubMed ID: 17065224
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  • 9. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
    Jana NR, Tanaka M, Wang Gh, Nukina N.
    Hum Mol Genet; 2000 Aug 12; 9(13):2009-18. PubMed ID: 10942430
    [Abstract] [Full Text] [Related]

  • 10. Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.
    Passani LA, Bedford MT, Faber PW, McGinnis KM, Sharp AH, Gusella JF, Vonsattel JP, MacDonald ME.
    Hum Mol Genet; 2000 Sep 01; 9(14):2175-82. PubMed ID: 10958656
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  • 11. Huntingtin interacts with a family of WW domain proteins.
    Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME.
    Hum Mol Genet; 1998 Sep 01; 7(9):1463-74. PubMed ID: 9700202
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  • 12. Molecular aspects of Huntington's disease.
    Walling HW, Baldassare JJ, Westfall TC.
    J Neurosci Res; 1998 Nov 01; 54(3):301-8. PubMed ID: 9819135
    [Abstract] [Full Text] [Related]

  • 13. Synaptic dysfunction in Huntington's disease: a new perspective.
    Smith R, Brundin P, Li JY.
    Cell Mol Life Sci; 2005 Sep 01; 62(17):1901-12. PubMed ID: 15968465
    [Abstract] [Full Text] [Related]

  • 14. Huntington's disease: a synaptopathy?
    Li JY, Plomann M, Brundin P.
    Trends Mol Med; 2003 Oct 01; 9(10):414-20. PubMed ID: 14557053
    [Abstract] [Full Text] [Related]

  • 15. A human HAP1 homologue. Cloning, expression, and interaction with huntingtin.
    Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ.
    J Biol Chem; 1998 Jul 24; 273(30):19220-7. PubMed ID: 9668110
    [Abstract] [Full Text] [Related]

  • 16. Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease.
    Truant R, Atwal RS, Burtnik A.
    Prog Neurobiol; 2007 Nov 24; 83(4):211-27. PubMed ID: 17240517
    [Abstract] [Full Text] [Related]

  • 17. Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.
    Valencia A, Reeves PB, Sapp E, Li X, Alexander J, Kegel KB, Chase K, Aronin N, DiFiglia M.
    J Neurosci Res; 2010 Jan 24; 88(1):179-90. PubMed ID: 19642201
    [Abstract] [Full Text] [Related]

  • 18. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W, Chaurette J, Pfister EL, Kennington LA, Chase KO, Bullock J, Vonsattel JP, Faull RL, Macdonald D, DiFiglia M, Zamore PD, Aronin N.
    J Huntingtons Dis; 2013 Jan 24; 2(4):491-500. PubMed ID: 25062733
    [Abstract] [Full Text] [Related]

  • 19. SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
    Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE.
    Mol Cell; 1998 Oct 24; 2(4):427-36. PubMed ID: 9809064
    [Abstract] [Full Text] [Related]

  • 20. Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease.
    Lecerf JM, Shirley TL, Zhu Q, Kazantsev A, Amersdorfer P, Housman DE, Messer A, Huston JS.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4764-9. PubMed ID: 11296304
    [Abstract] [Full Text] [Related]

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