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256 related items for PubMed ID: 12359756

  • 1. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.
    Pietras K, Rubin K, Sjöblom T, Buchdunger E, Sjöquist M, Heldin CH, Ostman A.
    Cancer Res; 2002 Oct 01; 62(19):5476-84. PubMed ID: 12359756
    [Abstract] [Full Text] [Related]

  • 2. Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.
    Sjöblom T, Shimizu A, O'Brien KP, Pietras K, Dal Cin P, Buchdunger E, Dumanski JP, Ostman A, Heldin CH.
    Cancer Res; 2001 Aug 01; 61(15):5778-83. PubMed ID: 11479215
    [Abstract] [Full Text] [Related]

  • 3. Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice.
    Kim SJ, Uehara H, Yazici S, Langley RR, He J, Tsan R, Fan D, Killion JJ, Fidler IJ.
    Cancer Res; 2004 Jun 15; 64(12):4201-8. PubMed ID: 15205332
    [Abstract] [Full Text] [Related]

  • 4. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma.
    Ostman A.
    Cytokine Growth Factor Rev; 2004 Aug 15; 15(4):275-86. PubMed ID: 15207817
    [Abstract] [Full Text] [Related]

  • 5. Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy.
    Timke C, Zieher H, Roth A, Hauser K, Lipson KE, Weber KJ, Debus J, Abdollahi A, Huber PE.
    Clin Cancer Res; 2008 Apr 01; 14(7):2210-9. PubMed ID: 18381963
    [Abstract] [Full Text] [Related]

  • 6. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors.
    Buchdunger E, Cioffi CL, Law N, Stover D, Ohno-Jones S, Druker BJ, Lydon NB.
    J Pharmacol Exp Ther; 2000 Oct 01; 295(1):139-45. PubMed ID: 10991971
    [Abstract] [Full Text] [Related]

  • 7. Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice.
    Weber KL, Doucet M, Price JE, Baker C, Kim SJ, Fidler IJ.
    Cancer Res; 2003 Jun 01; 63(11):2940-7. PubMed ID: 12782601
    [Abstract] [Full Text] [Related]

  • 8. STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake.
    Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, McSheehy P, Wartmann M, Ostman A.
    Clin Cancer Res; 2003 Sep 01; 9(10 Pt 1):3779-87. PubMed ID: 14506171
    [Abstract] [Full Text] [Related]

  • 9. Platelet-derived growth factor receptors: a therapeutic target in solid tumors.
    George D.
    Semin Oncol; 2001 Oct 01; 28(5 Suppl 17):27-33. PubMed ID: 11740804
    [Abstract] [Full Text] [Related]

  • 10. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases.
    Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ.
    J Natl Cancer Inst; 2003 Mar 19; 95(6):458-70. PubMed ID: 12644539
    [Abstract] [Full Text] [Related]

  • 11. Chemosensitization by STI571 targeting the platelet-derived growth factor/platelet-derived growth factor receptor-signaling pathway in the tumor progression and angiogenesis of gastric carcinoma.
    Kim R, Emi M, Arihiro K, Tanabe K, Uchida Y, Toge T.
    Cancer; 2005 May 01; 103(9):1800-9. PubMed ID: 15786421
    [Abstract] [Full Text] [Related]

  • 12. A stroma targeted therapy enhances castration effects in a transplantable rat prostate cancer model.
    Johansson A, Jones J, Pietras K, Kilter S, Skytt A, Rudolfsson SH, Bergh A.
    Prostate; 2007 Nov 01; 67(15):1664-76. PubMed ID: 17854058
    [Abstract] [Full Text] [Related]

  • 13. Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation.
    Servidei T, Riccardi A, Sanguinetti M, Dominici C, Riccardi R.
    J Cell Physiol; 2006 Jul 01; 208(1):220-8. PubMed ID: 16575905
    [Abstract] [Full Text] [Related]

  • 14. Combined low-dose imatinib mesylate and paclitaxel lack synergy in an experimental model of extra-osseous hormone-refractory prostate cancer.
    Corcoran NM, Costello AJ.
    BJU Int; 2005 Sep 01; 96(4):640-6. PubMed ID: 16104925
    [Abstract] [Full Text] [Related]

  • 15. Reversal of experimental pulmonary hypertension by PDGF inhibition.
    Schermuly RT, Dony E, Ghofrani HA, Pullamsetti S, Savai R, Roth M, Sydykov A, Lai YJ, Weissmann N, Seeger W, Grimminger F.
    J Clin Invest; 2005 Oct 01; 115(10):2811-21. PubMed ID: 16200212
    [Abstract] [Full Text] [Related]

  • 16. Improving chemotherapeutic drug penetration in melanoma by imatinib mesylate.
    Ogawa Y, Kawamura T, Furuhashi M, Tsukamoto K, Shimada S.
    J Dermatol Sci; 2008 Sep 01; 51(3):190-9. PubMed ID: 18485676
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.
    Pietras K, Ostman A, Sjöquist M, Buchdunger E, Reed RK, Heldin CH, Rubin K.
    Cancer Res; 2001 Apr 01; 61(7):2929-34. PubMed ID: 11306470
    [Abstract] [Full Text] [Related]

  • 18. A vascular endothelial growth factor receptor-2 kinase inhibitor potentiates the activity of the conventional chemotherapeutic agents paclitaxel and doxorubicin in tumor xenograft models.
    Emanuel S, Gruninger RH, Fuentes-Pesquera A, Connolly PJ, Seamon JA, Hazel S, Tominovich R, Hollister B, Napier C, D'Andrea MR, Reuman M, Bignan G, Tuman R, Johnson D, Moffatt D, Batchelor M, Foley A, O'Connell J, Allen R, Perry M, Jolliffe L, Middleton SA.
    Mol Pharmacol; 2004 Sep 01; 66(3):635-47. PubMed ID: 15322256
    [Abstract] [Full Text] [Related]

  • 19. Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient mice.
    Zheng X, Chang RL, Cui XX, Avila GE, Hebbar V, Garzotto M, Shih WJ, Lin Y, Lu SE, Rabson AB, Kong AN, Conney AH.
    Clin Cancer Res; 2006 Jun 01; 12(11 Pt 1):3444-51. PubMed ID: 16740769
    [Abstract] [Full Text] [Related]

  • 20. Differential effect of imatinib and synergism of combination treatment with chemotherapeutic agents in malignant glioma cells.
    Ren H, Tan X, Dong Y, Giese A, Chou TC, Rainov N, Yang B.
    Basic Clin Pharmacol Toxicol; 2009 Mar 01; 104(3):241-52. PubMed ID: 19159435
    [Abstract] [Full Text] [Related]

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