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Journal Abstract Search


217 related items for PubMed ID: 12361403

  • 1. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues.
    Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR.
    J Med Chem; 2002 Oct 10; 45(21):4755-61. PubMed ID: 12361403
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues.
    Carroll FI, Liang F, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR.
    J Med Chem; 2001 Jun 21; 44(13):2229-37. PubMed ID: 11405659
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues.
    Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR.
    J Med Chem; 2005 Nov 17; 48(23):7491-5. PubMed ID: 16279810
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation at nicotinic acetylcholine receptors of N-arylalkyl- and N-aryl-7-azabicyclo[2.2.1]heptanes.
    Cheng J, Zhang C, Stevens ED, Izenwasser S, Wade D, Chen S, Paul D, Trudell ML.
    J Med Chem; 2002 Jul 04; 45(14):3041-7. PubMed ID: 12086489
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists.
    Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR.
    J Med Chem; 2005 Feb 24; 48(4):1221-8. PubMed ID: 15715488
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.
    Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA.
    J Med Chem; 2007 Dec 13; 50(25):6383-91. PubMed ID: 17994682
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist.
    Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR.
    J Med Chem; 2001 Nov 22; 44(24):4039-41. PubMed ID: 11708907
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists.
    Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR.
    J Nat Prod; 2010 Mar 26; 73(3):306-12. PubMed ID: 20038125
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine analogues.
    Ondachi PW, Castro AH, Bartkowiak JM, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.
    J Med Chem; 2014 Feb 13; 57(3):836-48. PubMed ID: 24428686
    [Abstract] [Full Text] [Related]

  • 10. exo-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes: syntheses and nicotinic acetylcholine receptor agonist activity of potent pyridazine analogues of (+/-)-epibatidine.
    Che D, Wegge T, Stubbs MT, Seitz G, Meier H, Methfessel C.
    J Med Chem; 2001 Jan 04; 44(1):47-57. PubMed ID: 11141087
    [Abstract] [Full Text] [Related]

  • 11. Epibatidine structure-activity relationships.
    Carroll FI.
    Bioorg Med Chem Lett; 2004 Apr 19; 14(8):1889-96. PubMed ID: 15050621
    [Abstract] [Full Text] [Related]

  • 12. Stereoselective syntheses of (+/-)-epibatidine analogues.
    Kim YH, Won DY, Oh CY, Lee KY, Lee YS, Woo NT, Park YH, Park HJ, Ham WH.
    Arch Pharm Res; 2002 Feb 19; 25(1):45-8. PubMed ID: 11885690
    [Abstract] [Full Text] [Related]

  • 13. Epibatidine analogues as selective ligands for the alpha(x)beta2-containing subtypes of nicotinic acetylcholine receptors.
    Huang Y, Zhu Z, Xiao Y, Laruelle M.
    Bioorg Med Chem Lett; 2005 Oct 01; 15(19):4385-8. PubMed ID: 16039849
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and nicotinic binding studies on enantiopure diazine analogues of the novel (2-chloro-5-pyridyl)-9-azabicyclo[4.2.1]non-2-ene UB-165.
    Gohlke H, Gündisch D, Schwarz S, Seitz G, Tilotta MC, Wegge T.
    J Med Chem; 2002 Feb 28; 45(5):1064-72. PubMed ID: 11855986
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues.
    Ondachi PW, Castro AH, Sherman B, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.
    ACS Chem Neurosci; 2017 Jan 18; 8(1):115-127. PubMed ID: 27726337
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and structure-activity relationship studies of 3,6-diazabicyclo[3.2.0]heptanes as novel alpha4beta2 nicotinic acetylcholine receptor selective agonists.
    Ji J, Schrimpf MR, Sippy KB, Bunnelle WH, Li T, Anderson DJ, Faltynek C, Surowy CS, Dyhring T, Ahring PK, Meyer MD.
    J Med Chem; 2007 Nov 01; 50(22):5493-508. PubMed ID: 17929796
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine.
    Ondachi P, Castro A, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.
    J Med Chem; 2012 Jul 26; 55(14):6512-22. PubMed ID: 22742586
    [Abstract] [Full Text] [Related]

  • 18. ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.
    Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1998 May 26; 285(2):777-86. PubMed ID: 9580626
    [Abstract] [Full Text] [Related]

  • 19. Functionalization of the alicyclic skeleton of epibatidine: synthesis and nicotinic acetylcholine receptor binding affinities of epibatidine analogues.
    Wei ZL, Xiao Y, George C, Kellar KJ, Kozikowski AP.
    Org Biomol Chem; 2003 Nov 21; 1(22):3878-81. PubMed ID: 14664377
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues.
    Ondachi PW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.
    ACS Chem Neurosci; 2016 Jul 20; 7(7):1004-12. PubMed ID: 27166021
    [Abstract] [Full Text] [Related]


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